dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052949
Uniprot Accession H2KYH3; H2KYH3_CAEEL;
Genbank Protein ID NP_001024904.2;
Genbank Nucleotide ID NM_001029733.2;
Protein Name Suppressor of PAr-Two defect
Protein Synonyms/Alias
Gene Name spat-3
Gene Synonyms/Alias CELE_T13H2.5;T13H2.5;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
291KIRWFHESDEDGSVRPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
609TSKPGETSPDSSSKIPhosphoPep 2.019060867
913VVKVASPTAPIATENcurated18806794
1060LKHEKTVSDEEIEDFPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
1411RRPSRPCSSYDRPSSPhosphoPep 2.019060867
1420YDRPSSPSVVIRERLPhosphoPep 2.019060867
1429VIRERLGSDGALINRPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
1448CNIDKSRSRSPISRAPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
1450IDKSRSRSPISRAPVPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
Sequence
(Fasta)		MDDSPGPSTS KSARDKAENA EENTSDSSSD SEVSSASEKS EESRPSSEKK KVITRVIPVR 60
PPTRDKGHRV NLLESGNESE TKSLYQRAKE GIPSYKGKPE IKLPTTSEQY YDLEEVLMNP 120
ARMEGRELTL NAYDAVRNKY NVLPGKSVCE ADLQKVIGSF SCDVCQELIQ GSIMTKKCGH 180
RFCDQCILVA FMRSGNTCPT CRQNLGSKRE LQQDPRFDQL IYQVVESRSI VGRMMAENRE 240
HEKDVYFGRK GYIEGGSDWN KRYGIDPNSK LKAPRPLKSA GRKKIRWFHE SDEDGSVRKV 300
MESKKGAPKE DDTNYLENDK EGTSVAAEKE VLEEGEMDFP IEIKSSDEEQ TDLDDEEESM 360
LDSDFEISDN EDVSKPSCST SKKTTNRSRD SSESDNDSRD NELQKKKRKM KRKNVPKTDG 420
SDVSNESFDE DASGEVVATK LIKESKKKPC GRPKKKFAPE LIEGDIPTPS EDSLTSSDEE 480
RDDNAADPYA FVFQKEFNRD PRRDGHPEKD KLYNFDFMID MNHQVDRKFE KDGEIHVISD 540
DSNSEHESDE AEDRESSIDS EHEKEISKFL SHRQPLPNPT SVDDDCQVIT VVKKDVKQSA 600
ITSKPGETSP DSSSKIEEKP DKVSEEVSDD EMTPEHITAD KGTDTFLNNI MEHDDEMYGG 660
YLFRPGDTGI SRPKVQRAPG TNRLSMNVCP EAVYVVYPQP VLKEGKKKLV IPPEDYEISS 720
DETVTLSDSE ETSPSAEMEQ SETSEAGPST IIKTSGTERE TQGSSSPSEP STSRDRKMHK 780
RKLDTRRRKL ADDSDLSDFD VFSIDGNELV ATGKPIIKHK VFYDSANRMP SKSNLDFTGR 840
RNAREIPMEE ISRLAEEQVA HEEYKIHRRR QVVLEAVEAA SKKLNVYVDT TEEEEIEEEE 900
TPEEEVVKVA SPTAPIATEN PTTSTAPFEE GVAMKETPIE EIFFDPDEPC SSAQAAQREL 960
IIERVGKEQQ IIEDSLEQNR KPSSKTVKES ESREAQEPRI EKDEMESEQQ KKDADNPTVE 1020
VDKESEASSS ESDKSDFEDE TLDAQSKTVK ISLKHEKTVS DEEIEDFDTK FGEFVATADA 1080
KMIKRTIGEY VSTEFLKLVA QQPAVTDEVL ALGFCVRNTD QEFSTIKETG KRTNKNPDDV 1140
RLESMVKNFR ESFAAKHRPV PRKLPTNIER MYIERAHMVK YKHVVDMEPL HMKILIALQK 1200
QQIAATCANL SQPVTVTPEE HAEQVQLLHN LQNPSILRPL LNNPQFALTL HKAQQQAIQQ 1260
QRAQQKAQTQ KELAARQAEQ ARVEELARKR IAQEDAEKAL RQKGEQMSNV SGIPVSSDQN 1320
AQSSNAQQTG LIENQTTTTN SDSLTRPNTL ADNSHLGESQ QIPVIESIQS STSEALKESE 1380
NYKDMPILTP ASTVSSKSSA PATRRPSRPC SSYDRPSSPS VVIRERLGSD GALINRPPNR 1440
CNIDKSRSRS PISRAPVETV RINDHGQNET ILAGNITHTV ETTILEEGTS IGQDSTIRYD 1500
GECSTTQYID KTIDLDNSKN GTNVDEEQSN VLKLRENDLN REMLRYANRY HPSTMLAMGN 1560
LSINERHNKV QQVLASQELQ DLIARHTSGA VSQTQVEVVG GEGVCAGTSD AIGETDEDDD 1620
VEEEPEFTVD QLELAKKILK QRQGLESSED SDSDEDMVYD NVDGSVIRRA PHKKRETRKK 1680
KNIFVPNIPP KIRRKYVDKK IEMERAKYRA RIKSQKMASI RIAVPQKPTQ QFATPQQPVR 1740
GPGKHSAAAA ARATPKPKKA KMSNVQMSIV QPPLPLHQLQ GHMSAPTKIT AVPNVAAGFH 1800
QNQQQLYSDM AQAPQSTPIR TTPQPGTGSA PQAQTPQSHL AQLGQFVNGA NQQQAPQQQG 1860
MYTAAQLQAM QAAVAQTAQA AQAAYAAEAA YQAQVAQQAR AAPPQQLVQR QVPVGHPGQV 1920
NVPMPAQMLN QGNPQMAVNP AQAQMMDERR KMEEVNAVYH LMQSRGQFPP TNQELFQVQF 1980
AQAQADLRSA AAQAAQAAQA QAQMTNMRAQ AEAVARQQAM MKQEQARAQA AAKEAARLKA 2040
ETEAAKAKVQ AEAEARRKAE QEMRVRQAQA AQTQAAQAQA QSQAHAQNQA QTQAIVEIQR 2100
MIQSGQPLSM QQMQQLQQMS QVQMQHAQQV QQMQQMQMQQ LQMQQFAARM QQGTPKPAVS 2160
QQAVQQGMPA GIQGMPTGMG MQQLQGLGMP GMQLPQQAGQ SQQTSQAQQQ QLFMQLQLQQ 2220
QQLMQHQLQQ QLQMQQHQQH QQQQQQIQMQ QQQQLAQQGL VPNVSSAWLQ QQAQLAQQQQ 2280
QVVQQNLLMR VPSAQTPVAP RAPTVAPQSV VQQAPAPATP IAISVATTQV TRPETVEPFR 2340
SISSGTGTGT ERINNNVELE LWPTNGYSEK KRKEGSQASP IFGASAGDST FYHVACLIRS 2400
RSACNADDVG SLWVLRLEDQ TLLQFQLQQT LAEAQRFVGK QHLVIFYDDV MSGEVQQSKE 2460
YVINREFKPS NRQIPN 2477
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00097--zf-C3HC4
Gene Ontology

GO:0008270--F:zinc ion binding
GO:0033522--P:histone H2A ubiquitination
GO:0045814--P:negative regulation of gene expression, epigenetic
GO:0040027--P:negative regulation of vulval development
GO:0045138--P:nematode male tail tip morphogenesis
GO:0030334--P:regulation of cell migration
GO:0000003--P:reproduction