dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052741
Uniprot Accession G5EGT7; G5EGT7_CAEEL;
Genbank Protein ID NP_497536.2;
Genbank Nucleotide ID NM_065135.6;
Protein Name Eukaryotic translation initiation factor eIF5B
Protein Synonyms/Alias
Gene Name iffb-1
Gene Synonyms/Alias CELE_Y54F10BM.2;Y54F10BM.2;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
64FAALLDESEPEENYSPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
121DLDALLASFQEKDGPPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
171EPAVEEDSDGEGDEKPhosphoPep 2.019060867
311SVPAPRDSTEDEAAGPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
312VPAPRDSTEDEAAGVPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
392DDWEMAHSEDEASAQPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
Sequence
(Fasta)		MPPKKGGKKN KDDDWDDDAA EKKLAALSVA SNADAQWDDE EPKKAKTKAK APAKKGFAAL 60
LDESEPEENY SEPPEPEPEV KKAAKVPEKP EKEKKEKKKA GKKGKKGEAD EEEDLDALLA 120
SFQEKDGPKV AEVAPEAVAA PEAAPVDDKK SKKKKEKPVE KPEEPAVEED SDGEGDEKDQ 180
DKKDKKKQKK KDKKKEKEKK EKEDKKGGAG AKKGNLSLIK EMLKKQQEER EEQERLQKEQ 240
QERDAQEEKE RLEREHAEKE RKEAAKEAKR LEVERQKAAG TYQTAAQKRQ QALALEKLRA 300
AGHSVPAPRD STEDEAAGVK KSFVYVDEKT KAKQEEKKRR RLEKLGQLPV AAEASADASA 360
SASAEASAET PSTTPEQEKT PEPVDDWEMA HSEDEASAQK EKPKKPATKA SDADEDDDEE 420
SSDEESDEES EDSEESEESS SDDDEDRGGQ QKETVEERME RIKLRIAKRK EVAQANRSTD 480
NLRSPVICVL GHVDTGKTKM LDTIRRTNVQ QGEAGGITQQ IGATEVPAEA IKERCRQVRG 540
FLQDQMKIPG FLIIDTPGHE SFSNLRTRGS SLCDFAILVV DIMHGLEPQT IESLKLLIKG 600
KTPFVIALNK IDRLYEYESN PRKDVYELLK SQKPRVQAEF KERFNQIVVE FAEQELNVTL 660
SNHKNAEDSD YVCMVPTSAF LGDGIGNLMA FIINQTQTKY AQKLAFSEEL DATVMEVKAI 720
PGLGTTIDVI LVNGTMRAGD VIVLTGSDGA ITTQVRELLM PKPLKELRVK NEYIHYKEVK 780
GARGVKVLAK NLEKVLAGLP IYITDREDEV DYLRHEADRQ LANALHAIRK KPEGVYVQAS 840
TLGSLEALLE FLKSQNIPYS NVNIGPVHKK DVQKASAMKE HKAEYACVLA FDVKVEREAQ 900
IFADHEGVKV FQADIIYHLQ DAFLKYREEL KEKARRDNEH LAIFPCKLRV LPNHVYNTRN 960
PIVCGVSIEA GIVKRGTPIC VPSKEGIFLG TISSVQRNNE EVPSAKQGEE VCIKIENTTG 1020
EAPRLYGRHF THEDPLYSRV TRESIDICKK YFREDLTKAD WQLVVQLKKL LEIL 1075
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0342--GTP-binding
KW-0396--Initiation factor
KW-0547--Nucleotide-binding
KW-0648--Protein biosynthesis
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
IPR000795--TF_GTP-bd_dom
IPR023115--TIF_IF2_dom3
IPR009000--Transl_B-barrel
IPR004161--Transl_elong_EFTu/EF1A_2
PROSITE

PS51722--G_TR_2
Pfam

PF03144--GTP_EFTU_D2
PF11987--IF-2
Gene Ontology

GO:0005622--C:intracellular
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0003743--F:translation initiation factor activity
GO:0006413--P:translational initiation