| Tag |
Content |
| dbPAF ID |
dbPAF-0052731 |
| Uniprot Accession |
G5EGP4; G5EGP4_CAEEL;
|
| Genbank Protein ID |
NP_496436.1;
|
| Genbank Nucleotide ID |
NM_064035.6;
|
| Protein Name |
V-type proton ATPase subunit a |
| Protein Synonyms/Alias |
|
| Gene Name |
vha-6 |
| Gene Synonyms/Alias |
CELE_VW02B12L.1;VW02B12L.1; |
| Organism |
Caenorhabditis elegans |
| NCBI Taxa ID |
6239 |
Functional Description
(View all) |
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.Functional Description
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. |
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 150 | SKREAAMSISEAARG | Phospho.ELM 9.0;PHOSIDA;curated | 19530675; 21081558; 18806794 |
|
Sequence
(Fasta) | MGSIYRSEHM KLCQIFFQSE SAYQCVAELG ELGMAQFIDL NEEQNAYTRK FVNEVRRCDE 60
MERKINFVED EITKDLVPIP DYDEHIPAPQ PKHMGEMEAN LEKLEEELVQ INKNCKVLKN 120
NHVQLLEMKA VLEHVTSLLD PHSKREAAMS ISEAARGEAG PISFGMKDEF DKPVKDEKEL 180
KFVTGVVKRS KAIAFERFLW RLSRAKVFAK FIQIQEQTEL FSNEFEDKCV FILFFSGEQL 240
RAKVKKICDG FQAKCYTVPE NPAERTKLLL NIKVQTTDMK AVIEKTLDYR SKCIHAAATN 300
LRKWGIMLLK LKSIFHTLNM FSVDVTQKCL IAECWVPEAD IGQVKNSLHM GTIHSGSTVP 360
AILNEMETDK YPPTYFKLNK FTQGFQNIVD AYGIANYREV NPAPWTIISF PFLFAVMFGD 420
AGHGIIMLIA ASAFVIFEKK LISMKIKDEI FNTFFGGRYV VLLMGMFAIY TGFIYNDFYS 480
KSVNIFGSSW VNPYNQTLLA NMDAQGADSN TDLSLTFPPE IAFNHDYGPY PFGVDPVWNL 540
AINRLNFLNP MKMKTSILLG ISQMAFGIML SLMNHIGNRS VVDIVFVFIP QCLFLGCIFV 600
YLCLQVLMKW IFFYVKPAYI FGRLYPGSNC APSLLIGLIN MFMVKSRDAS FAHDVGTAAG 660
KEWVIVNGQN VTYTINDQCY LQQWYPNQSL VELILLLIAV VSVPVMLLVK PFYIRWRHSR 720
GLHIDLGHGP DEHGEFNFGD IMVHQAIHTI EFVLGCVSHT ASYLRLWALS LAHAQLSDVL 780
WTMVLRMSLT MGGWGGSAAI TILFYFIFSI LSVCILILME GLSAFLHAIR LHWVEFQSKF 840
YGGTGIQFEP FCFTKIIRVY EGLDQ
866Fasta Sequence
>G5EGP4|vha-6|Caenorhabditis elegans
MGSIYRSEHMKLCQIFFQSESAYQCVAELGELGMAQFIDLNEEQNAYTRKFVNEVRRCDEMERKINFVEDEITKDLVPIPDYDEHIPAPQPKHMGEMEANLEKLEEELVQINKNCKVLKNNHVQLLEMKAVLEHVTSLLDPHSKREAAMSISEAARGEAGPISFGMKDEFDKPVKDEKELKFVTGVVKRSKAIAFERFLWRLSRAKVFAKFIQIQEQTELFSNEFEDKCVFILFFSGEQLRAKVKKICDGFQAKCYTVPENPAERTKLLLNIKVQTTDMKAVIEKTLDYRSKCIHAAATNLRKWGIMLLKLKSIFHTLNMFSVDVTQKCLIAECWVPEADIGQVKNSLHMGTIHSGSTVPAILNEMETDKYPPTYFKLNKFTQGFQNIVDAYGIANYREVNPAPWTIISFPFLFAVMFGDAGHGIIMLIAASAFVIFEKKLISMKIKDEIFNTFFGGRYVVLLMGMFAIYTGFIYNDFYSKSVNIFGSSWVNPYNQTLLANMDAQGADSNTDLSLTFPPEIAFNHDYGPYPFGVDPVWNLAINRLNFLNPMKMKTSILLGISQMAFGIMLSLMNHIGNRSVVDIVFVFIPQCLFLGCIFVYLCLQVLMKWIFFYVKPAYIFGRLYPGSNCAPSLLIGLINMFMVKSRDASFAHDVGTAAGKEWVIVNGQNVTYTINDQCYLQQWYPNQSLVELILLLIAVVSVPVMLLVKPFYIRWRHSRGLHIDLGHGPDEHGEFNFGDIMVHQAIHTIEFVLGCVSHTASYLRLWALSLAHAQLSDVLWTMVLRMSLTMGGWGGSAAITILFYFIFSILSVCILILMEGLSAFLHAIRLHWVEFQSKFYGGTGIQFEPFCFTKIIRVYEGLDQ
|
| Keyword |
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0375--Hydrogen ion transport
KW-0406--Ion transport
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
|
| Interpro |
IPR002490--V-ATPase_116kDa_su
IPR026028--V-type_ATPase_116kDa_su_euka
|
| PROSITE |
|
| Pfam |
PF01496--V_ATPase_I
|
| Gene Ontology |
GO:0045177--C:apical part of cell
GO:0016324--C:apical plasma membrane
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0016471--C:vacuolar proton-transporting V-type ATPase complex
GO:0000220--C:vacuolar proton-transporting V-type ATPase, V0 domain
GO:0051117--F:ATPase binding
GO:0046961--F:proton-transporting ATPase activity, rotational mechanism
GO:0015991--P:ATP hydrolysis coupled proton transport
GO:0015986--P:ATP synthesis coupled proton transport
GO:0002119--P:nematode larval development
GO:0007035--P:vacuolar acidification
GO:0070072--P:vacuolar proton-transporting V-type ATPase complex assembly
|
