dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052729
Uniprot Accession G5EGK6; DIN1_CAEEL; E1B6R6; G5EBT0; G5ED50; G5EDA4; G5EEE3; Q8I124;
Genbank Protein ID NP_001022068.1; NP_001254306.1; NP_001254307.1; NP_496484.3; NP_496485.2; NP_871901.1; NP_871902.1;
Genbank Nucleotide ID NM_001026897.3; NM_001267377.1; NM_001267378.1; NM_064083.5; NM_064084.6; NM_182101.3; NM_182102.4;
Protein Name Daf-12-interacting protein 1
Protein Synonyms/Alias
Gene Name din-1
Gene Synonyms/Alias F07A11.6;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Isoform d: Probable transcriptional corepressor which modulates activity of the nuclear hormone receptor daf-12 to regulate the dauer diapause.
Phosphorylation Sites
dbPAF PTMs: 11
PositionPeptidesSourceReferences ( PMIDs )
115SPRNAELSPQRYGDTPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
129TRGAEVKSPSFRNQMPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
592SEAYQSRSFSPLNYQPhosphoPep 2.019060867
602PLNYQSQSPGYEFLEPhosphoPep 2.019060867
764PSLDESRTNRLSFDSPhosphoPep 2.019060867
768ESRTNRLSFDSTHHPPhosphoPep 2.019060867
1400DIPHEDVSDEEETEDPhosphoPep 2.019060867
1415GSRSRRQSTSSTISNPhosphoPep 2.019060867
1450PTGTPLLSPKILSPKPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
1472TSSTKRSSISDHENLPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
1880EEVKLETSPVPKEEPPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
Sequence
(Fasta)
MVQVPSTNTV KESRHVAISG LPSTLPDDRL QLHFTKFGEI QRLVRQHGNP EIVLVSYMDA 60
RGALRARSTK PQFEDSIEYK ISAYIPEPTQ NSSMASMSST PSSGQSSSPR NAELSPQRYG 120
DTRGAEVKSP SFRNQMEARR GGPHLSVQSQ QRHSREYWPI PEFPSESTAC VVYEIQSGST 180
PERDLFELVK KHSKRSGVPI DIQLESTTEP GWKKARVHYY RLDTDGLKAD KSLILGRPPK 240
FRVYYPTSGE QKHPQCHPST SYAIPKLKGD HLLKASCSVH VPHLDRHSPD HYRRRFESYG 300
QVIDVDMVKS NDNKAFAVVQ FTNIDDAQKA LQDTNIPKPM SYQSRPSHRI IIFYLPIECT 360
NEEIMLIIRS LSDRIVDICV DWWDRSAVIT LDDMEPANLL LKRMKLVGRN NFGEHKVAVD 420
FCSDRFNLYF INRKKENIEV AARSSSPTSK SENDQGSSSP SSSRDRQNLH DPLQTRSSVE 480
HHTNQEDQEN NASGSDSSSD SDSEEGSSSS NEDSDEQNDV DEEDDEDVVS EEKRHEPEEG 540
KSSSPGNGHR DESNGDKDHE DSSERFSQPS TSSHHETSHS PEKDSEAYQS RSFSPLNYQS 600
QSPGYEFLES KEIKQEFSPT TSSASSSDLE LDMEMPDNPL TRMLERMHWR PFIDVSSFVN 660
RIDEIVELNQ KARASYEKFT GRPFPKCNND EVLSIQKIVF HEPRDYYYYE NPCSELEVRI 720
RDWRKLSDTA DLDDFRATDS KELGRDQPAG GRTSGRPSLD ESRTNRLSFD STHHPAELAQ 780
RSHSLCIGPM TPSTPFPTSQ PLLVNTTHLP GTSQPSTSGG ITTPRSSQPP PLMSPVSRHN 840
SMSSTGRPAS IQTLRHQSVM FPPDVSIPPP PIPPTHDEMM APRGTPPSRR SSETMVPLRS 900
PPFGTPIQNL LTMPIVPPPH LIAATSTGTH SVSSSAHSTP RHSISGTPVH CEPSNSKTSQ 960
PPTPKSRPEK VQIRHDTISK SGPSNAINAL QARSQSMTSG DPKKSAPSTP VVRDAGSDLV 1020
AQIMSNQPNL GLRKLPRIEK KSSALQNIQN HQPPHSNANS TPSTPSTSTH QAMFKDKEKE 1080
RKKKEKEKEE REREARREMK RKETKEERNK RKEMERAKRL EDERQERKRE KKKERDERKK 1140
EKEKVRKKAE KEKLKKKKHR KGDSSDESDS DSNDELDLDV RKSTKEMTQE EKDHQLALLL 1200
SKGGIIENLK SRRRSDKRAH DSFEKMQQKS QQRRVLIESS DDEGGKDGDK GNSSNGEESD 1260
SEKADLPPPP APPSLSESAD QRLKVLKERE KGELTTSSDD EDHNDAGEIH QQRLTEDREN 1320
RKRQKSLTAY SSDEQGERKN VPKRMRRDDS EDAAAKHPGW SAKDDQKQRK RKLEHRRSSE 1380
DESKKNAKRD FRDIPHEDVS DEEETEDGSR SRRQSTSSTI SNVTAKERKE KSGKTPLRIV 1440
PEPTGTPLLS PKILSPKHLS PKTSTSSTKR SSISDHENLI SPRQRNRTTS STSTATTSSK 1500
HEALSIPEKP LSPPVTAKSS VSSIDDPSIR DEFSMNSAAD SPMSTTGRPM VLTKAAMKAF 1560
NSTPPKKKNS SSGQHDSSSG SSSDSSSSDG STSSDDSSDD EVPKQTEPVT SIPVVASDNG 1620
SPENVVVETP SIVSQTPREP EPFTISEQSS ESEPEAVPEC PEASVEPQME TSQNVEPVSE 1680
EHEDSHEHGD SEVAVESQQQ PLEHQEEKEE LENKILDVAA EHHEEQVQGD EDSVESSIPA 1740
PSDEPDPVTQ AQEKSAHTLI SDQETDQAVQ SIFDEEEADE FPQYPDFGIS TNEKEVSGKD 1800
PHNIKPTEPL NNGHTDLLFS PSSSAHASEK QSTKSEDDME EDSELVVMEK EVPMEQVIAQ 1860
EVHVPSEPSP MEEEVKLETS PVPKEEPIKM EESPEQTPTP DLISNNESQD TPGAVNNHLH 1920
ENHDAVQTPI QLQPASQHQV AQPSPRPAVA PDSQQNGPVL VSQQSQPSPM SSQQSDMAQN 1980
LILSSKDIND LAAKLHKNPE ALAQATRGDC SGIFQHLLLH AQGNGQNMTP EMLQLKAAFF 2040
AQQQENEANQ MMQAKMKQQT INKDRIKEQE RVKRMYEENE RKVEEDRREK QRKEEERQRL 2100
AAATAAATMA TQKAAEALKQ KQEVPRHGFQ HVLSMMTPEA RSLYEQFPGL SSYINRDSIG 2160
ATNGVLHLPT QSIQRPSSTA STSSNPPKAP LQPSASVNQN TIDPAEIEEI RVQRWFYKHF 2220
PMVWTGRLAL KSTEAMINLH LINGSETFLN DVLGRQVTEE NPRRDSVKIL QRLRLDNGQV 2280
EHIYRILTNP EYACCLALSS VNNIENLKEN DTNLKSHFID YLINKKIAGI SSLGEVETKF 2340
KSARVHVFAP GEIVNRYLSE LATSLHDYLQ NTDTRYLLIV FTNDKADPNM TGPPSVASLA 2400
VPPVSST 2408
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0694--RNA-binding
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR012677--Nucleotide-bd_a/b_plait
IPR000504--RRM_dom
IPR016194--SPOC-like_C_dom
IPR012921--SPOC_C
IPR010912--SPOC_met

PROSITE

PS50102--RRM
PS50917--SPOC

Pfam

PF00076--RRM_1
PF07744--SPOC

Gene Ontology

GO:0005634--C:nucleus
GO:0003676--F:nucleic acid binding
GO:0000166--F:nucleotide binding
GO:0003723--F:RNA binding
GO:0000398--P:mRNA splicing, via spliceosome
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated