dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052727
Uniprot Accession G5EGK1; G5EGK1_CAEEL;
Genbank Protein ID NP_490886.2;
Genbank Nucleotide ID NM_058485.5;
Protein Name TaLiN
Protein Synonyms/Alias
Gene Name tln-1
Gene Synonyms/Alias CELE_Y71G12B.11;Y71G12B.11;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
153GGGQNGGSTWNLKEKcurated18806794
807HEAARQVTSALDSLLPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
808EAARQVTSALDSLLEPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
812QVTSALDSLLEHAKCPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
820LLEHAKCSPKTQTTRPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
865ARKVVRHSQLLTEQFPhosphoPep 2.019060867
897AAKVAHATSEMILATcurated18806794
1063SANRLGTSLADLRTSPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
1470GISHPASSPGRAALIPhosphoPep 2.019060867
1685IGRLSALSGQIERSAPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
Sequence
(Fasta)		MGVLSLTVSS AEKGIKKTMQ FEPSTLIYDA AKLIREKFAM HDVNANEYGI FRLDENPSKS 60
LWMDNGRTFE HYLVRNKDEI EYKRKIRLLK VRMLDGAVKT ISVDESQPVS QLMMTVCNKI 120
GISNYEEYSL VRDDILMQNG GGGGGGGGQN GGSTWNLKEK ESRSKSSDRG GGGIYGTMRK 180
KNEQKLEELR KKLHTDEELP WLDHTKTLRE QGITEEETLI LRRKYFFSDS NVDSRDPVQL 240
NLLYVQCRDG ILRGLHPVEK ETAFQLAALQ SHIQYGDFPY DKPKFHLDGR DVLPKEYAKN 300
KENEKKVVAM YKELSGTSEL DAKSKYVHLC RGLKTYGVTF FVVKEKLPGK NKLVPRLLGV 360
NKESVMRVDE NSKQILKEWP LEQVRRWVPS AKCFSLDFGD YQDGYYSVQT TDGEKIAQLI 420
QGYVDIILKK KRTQDHQGIE GDEGSTMLED MVAPAKATLV AHGQIGSGQH ATDGLVAVRG 480
VLRTPQGGQG YGINGAQYGA VSGEITSQEL ARAQRLRYQD MYQHPQRALI GTIEATIRAV 540
EDAEIELEAE PQIDIPRFND DYSQNRWMEE QQAVNKENVN ERLAAMGAAT AQVVQWTAVE 600
EYDDRVGTAI ATIGSNLPDV SRNVRDLGAF MEHRERGDLL DATKKLCGAF GKFLNTVNPE 660
TEARRNEVFR TAGHVGETSQ HLINVMEAPN EGQQKFDERL VQSAKNVATS TAQLVLCAKT 720
ISAECDEPQV QERVIQSATK CAFATSQLVA CARVVAPTID NNACQQQLST AATEVTQSVN 780
NLLHDAEHAV YQQSSLTDIH EAARQVTSAL DSLLEHAKCS PKTQTTRREE EEMYNEVLRR 840
TNRMVVHQGP SEDLTREARK VVRHSQLLTE QFQHEAHQRP EHRERLLDAA AKVAHATSEM 900
ILATEQAESQ PRQVETEYAL RTAAERLGQV TNETTQEQQE QHIMQRLEQA AKQTAYDATQ 960
TISAANSAKD VIESRSYKEN LVYESTQTAG HLPNLITSIR ESQKVDNTPG EKFKAQSRLI 1020
RDSYKVLETS VRLFETARTA VPMVSDSHLA SSLDQSANRL GTSLADLRTS VNDAQQLNFS 1080
QQLLYSEELI KELDDQLVNT QKRAIARELP PIQNATSFSV SSKLMATTSN VGSGVAQLIT 1140
AAATSNDDKY VGTSAVELAQ GLRDFTDAIT EIVTVRTDIQ LDKLIVSARS VVHESGRVFD 1200
RVREKSAPTV LTDAAMNVST SLKQVISCLP DTKHIEKAIH EIQTAHTSAN IRPMEVRQAA 1260
NKFIEATSQL VVTIGSPDSR EAVDIFVRAY CDLHGSVVAQ LQRQSNMNNV KTAIIDRLEE 1320
AQRGSIGVLE TLRQAGNPSD HTLSQQFTSK TRELATTVNQ LVELSGMDGG ESRWQRECDA 1380
ALRRIQAVYH VTQHANVPLN DNGYFASLQS VSDGSRRLGE AMTGMARHAK GNDTEGFCTS 1440
VRDSADALCS LAESASHSAY LVGISHPASS PGRAALIDSS EVARSVESIN ASCQRVESRQ 1500
LNREELMSDI SSITKQSSSL AQLCRIASEK TQNPNVKKHL VGCAMGVASK TSSLVTAFKD 1560
LDRMPDAESR CTSSASELRQ VALQLLHFAD KPDFAAIQGS ISTEGHSAQQ PILQSSREML 1620
DSSAQMIQTA KSWASAPQDE ATWQRMAVNS RQVSDSIMRL VNAIHEAAPG QMELEAAIGR 1680
LSALSGQIER SAMDCYASGN VQKHGANAER QLLQQVQHIA SQLEDKVDDL HNAAVEHGER 1740
LPKVVQLHCQ MVEDLADAAC CAAGMTVDSN QQTELFDKCK TVVEAELAMM VASRESGGNP 1800
NAVHAHANVK DAAGQLKHAI GDMRQTIAKV SSEQGAVQGM VDTISSSIAH TDVAVSSAHP 1860
GSSFADAQTR MTAYLEDIRR TAIEMPTLNT TDLGAASLNL SEKYRLVAGD VRQAAGMLPE 1920
ADIGQRLKLA VQKLGTSCIE TVTVAGGKRA HPEDERIQRQ LSSQAGTVVE RVEQVLAALH 1980
SASRGTQACI NAANTVSGII GDLDTTIMFA TSGSLNSSDD RKFPSHKEAI VKTAKALVED 2040
TKALVAGAAS NQEQLAVAAQ NAVRTIVNLS DAVKTGAVSL SSENSETQVL VIHAVRDVAA 2100
ALTSLIQATK NASGLSLQHP AMGHLKDAAK VMVSNVARLL KTVATVEEKN QQGTRAVEAA 2160
VDAIGFEMKQ FEHDLNEGAA IPTDFRPEHL QQTAEHVSEI TKRVMQGADA PQSEEEIIGV 2220
ANLSRSAVRS LLAVVRTISN DADTAPQRYA VLDSGRDVAN NVKSLLVSLH TQMVRNPGQE 2280
ESRRLLLEAS KGVSSALSHL VGLCNEMTGL PHNHEMESAA AQAENELLGA ASSIEAASAK 2340
LAELRPRQIV QENTQEIVET EFDDNIIISA KGILHAVHTL MRSASNAQRE LAMQGRAAAG 2400
GTGTYQWSEG LISAARVVVA SVHKLCDAAN TLMKGQTTEE RLISAAKQVS SSTAQLLVAC 2460
NVRADPDSQA NRRLQAAGQA VRNAAERLVQ SAQQEMIARD DRNIAISDRL VNGIAQVMDA 2520
QEEVLRKERE LGEARHKLAH LNKARYERDG EEA 2554
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0401--Integrin
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR019749--Band_41_domain
IPR014352--FERM/acyl-CoA-bd_prot_3-hlx
IPR019748--FERM_central
IPR019747--FERM_CS
IPR000299--FERM_domain
IPR032425--FERM_f0
IPR018979--FERM_N
IPR002558--ILWEQ_dom
IPR002404--IRS_PTB
IPR011993--PH/PTB_dom
IPR015224--Talin_cent
IPR015009--Vinculin-bd_dom
IPR006077--Vinculin/catenin
PROSITE

PS00660--FERM_1
PS00661--FERM_2
PS50057--FERM_3
PS50945--I_LWEQ
Pfam

PF16511--FERM_f0
PF00373--FERM_M
PF09379--FERM_N
PF01608--I_LWEQ
PF02174--IRS
PF09141--Talin_middle
PF08913--VBS
Gene Ontology

GO:0005856--C:cytoskeleton
GO:0005925--C:focal adhesion
GO:0031430--C:M band
GO:0001726--C:ruffle
GO:0055120--C:striated muscle dense body
GO:0005200--F:structural constituent of cytoskeleton
GO:0007155--P:cell adhesion
GO:0007016--P:cytoskeletal anchoring at plasma membrane
GO:0007229--P:integrin-mediated signaling pathway