dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052709
Uniprot Accession G5EG81; G5EG81_CAEEL;
Genbank Protein ID NP_495931.4;
Genbank Nucleotide ID NM_063530.4;
Protein Name Ubiquitin carboxyl-terminal hydrolase
Protein Synonyms/Alias
Gene Name CELE_T24B8.7
Gene Synonyms/Alias T24B8.7;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
89DEGPRKRSASPATANPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 18806794
91GPRKRSASPATANQSPhosphoPep 2.019060867
204VRNQFVESDEEDVAEPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 18806794
Sequence
(Fasta)
MLRVHCKRSK EWHNCNIGCR QAAIILDKDG LESDRGDAAR SPVTPASESD SVDLDMPAGE 60
SANSPIDGDT APLNVSNNES GDEGPRKRSA SPATANQSSW GDNPAKKICT EGIDLWVQST 120
SEATAVPDVS QQYQDNQDML ITMGFKSEEI DTALRLSNND VEKAIQYLTR EISGLDSAPI 180
TASSSVEKSK YPLNDLVRNQ FVESDEEDVA EEMRTVWDDA SMARIKTILE NNHKYVIFHQ 240
NGTLHRRLIV ATNILRSGKH ERMSEVLNFV DEFMSFIIGR HVNCSDVRPG FELLRQLLEL 300
QPPYIGEPEA HAIEQFYIAI TPMLCARLTI TPSSVKTVLA IDEMFNFRNK FFIQGVQYID 360
LPEREFPPLK YIDLERLERL EYKRIYAYLA DVFVDALIPM IDEKVDAIGD EDTSEVTLLD 420
LQCLLRALNI FSNFMHRGND LFLCKLETWI SKSLDRFRIV NDKEVRDALI RRQGLDLLQE 480
IVILCDRFGL EVATTTQSAR LNYLRKWIKC PQMESILHAL EELGTIADRF HRTGGMTITR 540
PKSHVNEEFF KKWLEENKVL QIVLTGNMDH VVYVERIQPI LQYMTPELTF DDLKFVWSLR 600
KGRMGVSVDN FNKIMEFISK SVNNEQIEWL IELFKKSFRS RETRLYEPIF NFSYTIAIQK 660
DRDDECKLKI CNVIWELIHI ARGPPRCGSF KAIEHGMKKH CDLLGMMFDK SERDSFLTNM 720
MDGLNVDEGF NEITVVYLFI MLDKLKRTFT PKRSTHGDET LSRVNELKAS LRERKLADPL 780
LDRLENIRHV AHERFEASLN ANQDSQSNAV FESTNDVFGS HHVDNILTTS VYGCTDYGFV 840
LQNTLRLLKW LHDVDASIVD VEYVQRLFKI FIEQSDSKPQ EKTEIFGFLF EVRMVLMRPE 900
TSRAIITHLC GMDIFTLQIT GLRCFCKYWE ELPILSNEES RPVESFIVKL QKDNECKLFV 960
WKLILFNQFD DVVEKCMETF CERDLVLVES PYSVRHHTYS FLSVFSFYVE KLKSELYKRS 1020
GKPLTEISYD TTELTMNEDE IKQHDVPLDG MLTETIVRAL NRLVRFMTRF VELGNEKNHM 1080
IRENPSHGSS ISGHAVTFNI ELKNDDDDID CGLNAWKTLI CDSSTTVGEF KVRIAKRLHF 1140
HEGMTEFTVH KREDDLTMGE ANLRYDFLTL QSVKLASETD SVFLSEKLRI LVKPKKSSNR 1200
RSDLQNHQYS QKKALREDFL PMSIISKCNF YDLLHELASN GDKYIRASVR RLLLLLPTQP 1260
SILKQITFGD MDDDEDEPLT IKINNMCAEY MTPMEPGRML YALEAISSVV APTRLTAQAT 1320
EDATELTNAL LEIDVIKNLT DGVLTKPNVI PLNKCSPGDR HSIFERIIQI IRSVYTGRNT 1380
FIKMIRNEFR IREEMRKTCE RMLQSRQTPR SIDQPMDYAL TKQQIMPPPC VDNQNNPAYS 1440
SSGSVVQFKS LFSSYIKIIT SFMQRWDLPD LIAFLESIRN FQWIHVATES LLTSEIEPFA 1500
ETNQNKGKKT RETASDLIRA VVKGERWGDE CRLIIVKKAF SLIRHMVREW VGSHGDIAAP 1560
LLETLFLNNS WVQFYQDVLV NSQQEAYRKY VQENIVKIGK DSFEITCVSL KMLLEMFMSL 1620
PLHDGFTSDL NELQRRQRQH CDGIVQTVVE IFYFESPRRC REDQKDIDWS QLGHKPIEII 1680
RDQIKSLLGF KPRFCTTNND LALTENIYAA AKMRMISCLL PYCSQSDIED CSKAFIDAII 1740
NDFLFPELPD IEDSMFEEES IRWEYQAREA AIQTLNAFCE RSYKNSHQLL NMWSKFMIAQ 1800
KTYDPSYRPI IRGRQFDKVG MKNDGGTCYM NAMIQQLVHV PGLSRELIAL QNIDPQLRWG 1860
DNTAALLCEL QRVFAQLNFA QCQAIVPEGL WKEFRFEPDM PLNTKQHHDA IDFYSILLDK 1920
CDNVLKKLEL PPLFQNRFFG KYSYEKICYG CWHRYKSPDE EFNCISLALS GDNLEEALEN 1980
FLAAHVMEGE NAYHCEKCDE KKTTLNRTSF LELPSTMTIQ LKRFTYDLVN NMIRKDNQLF 2040
RFPFEIDMTP YMTTSRHVPD EHVQDLFDEM LYGNGEADEA PSPPHKNGVA EKPNLGSGSA 2100
STPSLESAQK KMFRRHRSST MRLSQSFANT SGFDTPSQQK PLIYELVGVL AHSGIATAGH 2160
YYSFIKERRE EFRDSPHYNK WHHINDMIVS PMSFNNIEDL WYGGTFTQEG VFIGLDERVR 2220
HWNAYVLFYE KKRDEPTALI PRHIIDRLND VKPKVTFDVS DEIMDDGEDK MKAVQDALKK 2280
DMSEARKLRI RMFNSMDLKM KKFLNDDYCK FLDDRDFFSF DLYQIYINSL LPLLKREETV 2340
EYTVTDLDKA DFFKLAFEYI ASYIIRVAWM MFDEHRPKNF PRAATDLIRL LLLRHPDNKM 2400
FFFKSLEANN SEMLTRMLET TEHDIRASFW HCMRSALRLW VLENGNKDEN MMEPSPDSTD 2460
LDDDDEEDDE DDEDDDLEDE DSETEEMFRQ DMMRPSPMAL VSQLVMNQSR PPQLKPMLPV 2520
DLSKARSQRL NIVRRIVQVL PFRIHRMEGS GRHYSRSLVE MLYMISRLNE FGKSVLHVCN 2580
ALQLVGEFLW EDYSTVFCRL RFSEDRIKGL GLWPYLPGLY FELLLDTMNR SLLHIIDPHL 2640
HYRHLLMTTQ GKFMNESLAL YCASREEHET TEGKSVNDEK SLHSRIVLCY VRQIQLIVRS 2700
EVPDAAQEYI FNACQILLKA FLKDVQYMFT SIEHWSHVID FFIDLAQRLV RVDLSSLGAC 2760
LLKNLMWVGI AEDDDTVEPG VLPVMLEWKE TDYTKYRKMN EALFNIRIIK HPELRAVLLR 2820
CSKRFRSIFK MSYAENDIDS DEPMDESDEV MIGPQLLKRA TNSTDLTRSA VPSACATARV 2880
IETKEINLEE DLKANLSAAS LEMTEQPSLE EVLSVDSSEE DISMIALSEN PGAEDNEK 2939
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR013763--Cyclin-like
IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005634--C:nucleus
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:ubiquitin-specific protease activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0061136--P:regulation of proteasomal protein catabolic process