| Tag |
Content |
| dbPAF ID |
dbPAF-0052694 |
| Uniprot Accession |
G5EFV5; CDK7_CAEEL;
|
| Genbank Protein ID |
NP_490952.2;
|
| Genbank Nucleotide ID |
NM_058551.6;
|
| Protein Name |
Cyclin-dependent kinase 7 |
| Protein Synonyms/Alias |
|
| Gene Name |
cdk-7 |
| Gene Synonyms/Alias |
Y39G10AL.3; |
| Organism |
Caenorhabditis elegans |
| NCBI Taxa ID |
6239 |
Functional Description
(View all) |
Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. Required for maintaining chromosome ploidy. May phosphorylate the large subunit of RNA polymerase II, ama-1.Functional Description
Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. Required for maintaining chromosome ploidy. May phosphorylate the large subunit of RNA polymerase II, ama-1. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MSRRYDTIKH LGEGQFANVY LAQDLESGEC VAIKKIKLGS REEAKDGINR TAIREIKLLK 60
EIHHDNIIGL RDVIGHRTSI QLVFDFMDTD LEHVIKDKEI ILMPAHIKNI TMQMLLGLEF 120
LHVHWILHRD LKPNNLLMNK MGRVKLTDFG LARFFGSPNR NYTHQVVTRW YRAPELLFGA 180
RSYGVGIDIW SVGCIIAELL LRNPIFPGES DIDQLVKIFN ILGCPTPETW PNMTEMNSYV 240
IIKPQTEYMA LNYYFSAAPQ DLLDLMAGMW TFDPIKRLTC TQSLQMEYFR TQPFCCLDEE 300
LPLPKKQQPQ KRSRRLDDDG TRPVRRLNFD
331Fasta Sequence
>G5EFV5|cdk-7|Caenorhabditis elegans
MSRRYDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHHDNIIGLRDVIGHRTSIQLVFDFMDTDLEHVIKDKEIILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPNRNYTHQVVTRWYRAPELLFGARSYGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIKPQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYFRTQPFCCLDEELPLPKKQQPQKRSRRLDDDGTRPVRRLNFD
|
| Keyword |
KW-0067--ATP-binding
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
|
| Interpro |
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
|
| PROSITE |
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
|
| Pfam |
PF00069--Pkinase
|
| Gene Ontology |
GO:0005675--C:holo TFIIH complex
GO:0005524--F:ATP binding
GO:0004693--F:cyclin-dependent protein serine/threonine kinase activity
GO:0008353--F:RNA polymerase II carboxy-terminal domain kinase activity
GO:0051301--P:cell division
GO:0045448--P:mitotic cell cycle, embryonic
GO:0009299--P:mRNA transcription
GO:0006468--P:protein phosphorylation
GO:0006355--P:regulation of transcription, DNA-templated
|
