Tag |
Content |
dbPAF ID |
dbPAF-0052682 |
Uniprot Accession |
G5EFR6; G5EFR6_CAEEL; |
Genbank Protein ID |
NP_501709.2; |
Genbank Nucleotide ID |
NM_069308.5; |
Protein Name |
Calcium-transporting ATPase |
Protein Synonyms/Alias |
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Gene Name |
mca-1 |
Gene Synonyms/Alias |
4K392;CELE_W09C2.3;W09C2.3; |
Organism |
Caenorhabditis elegans |
NCBI Taxa ID |
6239 |
Functional Description (View all) |
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.Functional Description
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
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Phosphorylation Sites
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dbPAF PTMs: 2 |
Sequence (Fasta) | MQKSQNVTAV TETNGVAAAL GGHHTSPDTN AGKTKDAKEF GCSLGDLRGL MEARGAEAIV 60 RLSTEHEGVE GLCKKLKTDS LVGLNGEQAD LDRRRHVYGA NTIPPAKSKG FVRLVLDACK 120 DPTLVILVLS GFINLALSFY EPTSAAEDAT QHLVNATTAA ILANGTFMST TEAPSEGHGT 180 AWIEGVAILL CVIVVVLVTA VNDYSKERQF RSLQEKIETG QKFSVIRNGE AIDVPVSDLV 240 VGDIARVKYG DLLPADGFLI QSNDLKIDES SLTGESDHIK KSIESDPVLL SGTYAMEGSG 300 KMLITAVGVN SQTGIIMTLL GAGKAGIGDD DSTSTSSSSS SSSSSSGSSS NGSSDSSKSG 360 DDDLTAKSVL QAKLSKLALQ IIYCGTTIAI IALIVLVTRF CLDHYVFEKN EFSLVDIQMF 420 VKFFIIAVTI LVISIPEGLP LAIALALTYS VRKMMHDNNL VRHLDACETM GNATSICSDK 480 TGTLTTNRMT VVQSYINGNH YTSQEAQPHG ANLPGSTGPI LMEAISVNCA YNSMIVEPTK 540 AGEQIQQLGN KTECGLLGFV NRLGGDYAAI RKKFPEHDLT KVYTFNSSRK CMMTVVPYAE 600 NGQNIGYRVY CKGASEIVLG RCTYLIGSDG KPHQLTGDRL KEITSTIIHE MANSGLRTIC 660 VAYKTIIKKG TRDVEKTEIE FAEDSDIDWD DEDAMYQNFT GIAICGIQDP VRPEVPVAIS 720 KCKKAGITVR MVTGDNIMTA RAIAMSCKIL EPGEDFLALE GKEFNERIRD ENGKVSQAKL 780 DEIWPRLRVL ARAQPADKYT LVKGIIDSKA TPQREIVAVT GDGTNDGPAL KKADVGFAMG 840 IAGTDVAKEA SDIILTDDNF TSIVKAVMWG RNVYDSISKF LQFQLTVNVV AVITAFVGAV 900 TVSDSPLKAV HMLWINLIMD TLASLALATE QPTDELLERK PYGRKKSLIS RTMVKNILCH 960 ALYQLIIIFV IFFYGDTIFG IKTGLYAPLF APPSQHFTLV FNAFVMMTVF NEINARKVHG 1020 ERNVFKGLAS NRVFCVIWVT TFIAQIIIVQ FGGAWFSTAP LTLQQWIVCL VLGFSTLIWG 1080 QIVATIPSKK LPKAWKVGKG EVQPANLHIN GDYNVRARSR AVTLRRSGKS LWVRGMFIIG 1140 NHLRVLRAFG MEKSEKAAFG RTAPAMTAEA AERWRASYRK YRHQKHQEKK ATAETAESVK 1200 SADWAKEQKE KKKTFKQIKQ VARGKSLDKD SKKHHKKRKD QTNVDMEDIE LN
1253Fasta Sequence
>G5EFR6|mca-1|Caenorhabditis elegans MQKSQNVTAVTETNGVAAALGGHHTSPDTNAGKTKDAKEFGCSLGDLRGLMEARGAEAIVRLSTEHEGVEGLCKKLKTDSLVGLNGEQADLDRRRHVYGANTIPPAKSKGFVRLVLDACKDPTLVILVLSGFINLALSFYEPTSAAEDATQHLVNATTAAILANGTFMSTTEAPSEGHGTAWIEGVAILLCVIVVVLVTAVNDYSKERQFRSLQEKIETGQKFSVIRNGEAIDVPVSDLVVGDIARVKYGDLLPADGFLIQSNDLKIDESSLTGESDHIKKSIESDPVLLSGTYAMEGSGKMLITAVGVNSQTGIIMTLLGAGKAGIGDDDSTSTSSSSSSSSSSSGSSSNGSSDSSKSGDDDLTAKSVLQAKLSKLALQIIYCGTTIAIIALIVLVTRFCLDHYVFEKNEFSLVDIQMFVKFFIIAVTILVISIPEGLPLAIALALTYSVRKMMHDNNLVRHLDACETMGNATSICSDKTGTLTTNRMTVVQSYINGNHYTSQEAQPHGANLPGSTGPILMEAISVNCAYNSMIVEPTKAGEQIQQLGNKTECGLLGFVNRLGGDYAAIRKKFPEHDLTKVYTFNSSRKCMMTVVPYAENGQNIGYRVYCKGASEIVLGRCTYLIGSDGKPHQLTGDRLKEITSTIIHEMANSGLRTICVAYKTIIKKGTRDVEKTEIEFAEDSDIDWDDEDAMYQNFTGIAICGIQDPVRPEVPVAISKCKKAGITVRMVTGDNIMTARAIAMSCKILEPGEDFLALEGKEFNERIRDENGKVSQAKLDEIWPRLRVLARAQPADKYTLVKGIIDSKATPQREIVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVITAFVGAVTVSDSPLKAVHMLWINLIMDTLASLALATEQPTDELLERKPYGRKKSLISRTMVKNILCHALYQLIIIFVIFFYGDTIFGIKTGLYAPLFAPPSQHFTLVFNAFVMMTVFNEINARKVHGERNVFKGLASNRVFCVIWVTTFIAQIIIVQFGGAWFSTAPLTLQQWIVCLVLGFSTLIWGQIVATIPSKKLPKAWKVGKGEVQPANLHINGDYNVRARSRAVTLRRSGKSLWVRGMFIIGNHLRVLRAFGMEKSEKAAFGRTAPAMTAEAAERWRASYRKYRHQKHQEKKATAETAESVKSADWAKEQKEKKKTFKQIKQVARGKSLDKDSKKHHKKRKDQTNVDMEDIELN
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Keyword |
KW-0067--ATP-binding KW-0106--Calcium KW-0109--Calcium transport KW-0181--Complete proteome KW-0378--Hydrolase KW-0406--Ion transport KW-0472--Membrane KW-0547--Nucleotide-binding KW-1267--Proteomics identification KW-1185--Reference proteome KW-0812--Transmembrane KW-1133--Transmembrane helix KW-0813--Transport
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Interpro |
IPR006068--ATPase_P-typ_cation-transptr_C IPR004014--ATPase_P-typ_cation-transptr_N IPR023299--ATPase_P-typ_cyto_domN IPR018303--ATPase_P-typ_P_site IPR023298--ATPase_P-typ_TM_dom IPR008250--ATPase_P-typ_transduc_dom_A IPR023214--HAD-like_dom IPR006408--P-type_ATPase_IIB IPR001757--P_typ_ATPase
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PROSITE |
PS00154--ATPASE_E1_E2
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Pfam |
PF00689--Cation_ATPase_C PF00690--Cation_ATPase_N PF00122--E1-E2_ATPase PF08282--Hydrolase_3
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Gene Ontology |
GO:0005829--C:cytosol GO:0005887--C:integral component of plasma membrane GO:0043231--C:intracellular membrane-bounded organelle GO:0016020--C:membrane GO:0005524--F:ATP binding GO:0005388--F:calcium-transporting ATPase activity GO:0005516--F:calmodulin binding GO:0046872--F:metal ion binding GO:0030165--F:PDZ domain binding GO:0006816--P:calcium ion transport GO:0098655--P:cation transmembrane transport GO:0006874--P:cellular calcium ion homeostasis GO:0051480--P:cytosolic calcium ion homeostasis
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