dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0052675 | ||||||||
| Uniprot Accession | G5EFL0; GLD4_CAEEL; | ||||||||
| Genbank Protein ID | NP_492446.3; | ||||||||
| Genbank Nucleotide ID | NM_060045.4; | ||||||||
| Protein Name | Poly(A) RNA polymerase gld-4 | ||||||||
| Protein Synonyms/Alias | Defective in germ line development protein 4;Germline development defective-4; | ||||||||
| Gene Name | gld-4 | ||||||||
| Gene Synonyms/Alias | ZK858.1; | ||||||||
| Organism | Caenorhabditis elegans | ||||||||
| NCBI Taxa ID | 6239 | ||||||||
| Functional Description (View all) |
Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. The enzymatic activity is enhanced by its interaction with gls-1. Required, together with gld-2, for early meiotic progression in male and female germ cells and for gld-1 protein accumulation in the hermaphrodite germline. In the germline, forms a complex with gls-1 which directly binds to gld-1 mRNA and prevents its degradation. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MNEDSRLSSS QQPSTSTPRS SIPSTMNSDE PNTCRRLSQS QEQPSTSRTC KSETPEFGYS 60 DSLPFAPWRR KRYGLNIQGL HEEIVDMYHW IKPNEIESRL RTKVFEKVRD SVLRRWKQKT 120 IKISMFGSLR TNLFLPTSDI DVLVECDDWV GTPGDWLAET ARGLEADNIA ESVMVYGGAF 180 VPIVKMVDRD TRLSIDISFN TVQGVRAASY IAKVKEEFPL IEPLVLLLKQ FLHYRNLNQT 240 FTGGLSSYGL VLLLVNFFQL YALNMRSRTI YDRGVNLGHL LLRFLELYSL EFNFEEMGIS 300 PGQCCYIPKS ASGARYGHKQ AQPGNLALED PLLTANDVGR STYNFSSIAN AFGQAFQILL 360 VAVTLRERKG KNHVAMRAYK GSLLHLIMPF TSKELTYRNW LMSGVLSMPG QEAPASYDLN 420 QLHNTLVSPM VDLSRYAWLR KAPAKAEKRD SRPLTIVNPA DDRQTLAQQL KKQILEQTEA 480 KKSLEKMPAC DDNKKEEELV ATRETDVELE AEDTESEGHH NGENDLILTG PPLPTSTQSV 540 NTSATVSTAA SISEREDTDS PGLSSSMGNQ SSEEDEDNGI NNRNNSAVPV QFKKPFNEVV 600 AQPARESKRT QTTSEDKMQD QFHFNGYSYP PPSRYAAGTA APSHKHRNAH PQRQRPSIRN 660 LSQGSDGSDE YNVESWNNNI RQGRRASSNS PSPSRQQTNT RNCGPTNNIP YDSFRSQNKN 720 STLDGSNNSS EEPITMYADV VKKKSSITTS TNTSTADVNV TNGNPIPANG IIPQSMAVVN 780 VGRGSYRNAL TTSPMTPPSA HTSMQKQHHL RKDNECGFDN NSATSSTDLS HHQPQLVPPV 840 NRLQR 846 |
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| Keyword | KW-0067--ATP-binding |
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| Interpro | |||||||||
| PROSITE | |||||||||
| Pfam | |||||||||
| Gene Ontology | GO:0005737--C:cytoplasm |