dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052665
Uniprot Accession G5EFD4; G5EFD4_CAEEL;
Genbank Protein ID NP_001022812.1;
Genbank Nucleotide ID NM_001027641.3;
Protein Name Heavy Metal Tolerance factor
Protein Synonyms/Alias
Gene Name hmt-1
Gene Synonyms/Alias CELE_W09D6.6;W09D6.6;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
58NNNYRRMTDDDASSTPhosphoPep 2.019060867
793IAEQRAKSIELGEELPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
Sequence
(Fasta)
MGFSPFLDEC RAEGLWPIGP SCNKIISFGV YTFFIVVNFI VLCIPNSNSA NNNYRRMTDD 60
DASSTSKLTI SKILSICTIF AVICQSIFYF CFTFYFHPYT HLLLAFCVSK LFFWILSLCS 120
FSKWRNQPST PISLAFAFSA ALLIHCIPLT DWKKYFEPTS KNRGDLTFYI IELALVTVVF 180
FFTIVTGLFN FSGCSSRESA WNNLSKKVVT VAPYIWPTKS ISLQLRVVFC LFLLIIGRLI 240
NVSLPILSKW IVDELATPDT FQYSLLFLAT FLKFLQGNGA MGGFLNTVRT YLWIPIQQYT 300
TRELEVELFK HLHSLSLRWH LSRKTGQVLR VMDRGTSSVN NILNYILFNV VPTIADIVIA 360
VIFFFSAFNA YFGLIVFGTM ALYLTVTISI TEWRTQYIRE ANEKDNATSA IATDSLINYE 420
TVKYYGNEEF EVNRFKNAIE SYQVTEWKTQ ASLAFLNCLQ NAIIGIGMIG GSVFVVYMIV 480
HEKTLTVGDY VLFTTYLLQL YTPLNFFGTI YRVIQKAFVD MENMFDLMND EVEVKDLPHA 540
LPYTDPRGTI SVKNLTFEYN TGLPVIKNIS FEIGNGQTVA LVGSSGSGKS TLIRLLFRLF 600
ESTEGSIEFD GIDVRNYTMH SLRQQIGIVP QDTVLFNDTI MYNIRFGRPD ASDEEVIEAA 660
KAAMIHEKIT SLPEGYATMV GERGLKLSGG EKQRVAIART ILKKPQFIFL DEATSALDTP 720
TERAIQKCLE KLCKSRTGVV VAHRLSTVVN ADLILVLDKG IILERGNHKE LLAQQGTYAS 780
MWEAQIAEQR AKSIELGEEL P 802
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003593--AAA+_ATPase
IPR011527--ABC1_TM_dom
IPR003439--ABC_transporter-like
IPR017871--ABC_transporter_CS
IPR027417--P-loop_NTPase

PROSITE

PS50929--ABC_TM1F
PS00211--ABC_TRANSPORTER_1
PS50893--ABC_TRANSPORTER_2

Pfam

PF00664--ABC_membrane
PF00005--ABC_tran

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005774--C:vacuolar membrane
GO:0005524--F:ATP binding
GO:0042626--F:ATPase activity, coupled to transmembrane movement of substances
GO:0015086--F:cadmium ion transmembrane transporter activity
GO:0070574--P:cadmium ion transmembrane transport
GO:0071585--P:detoxification of cadmium ion
GO:0010273--P:detoxification of copper ion
GO:0046686--P:response to cadmium ion