| Tag |
Content |
| dbPAF ID |
dbPAF-0052428 |
| Uniprot Accession |
G5E8Q8; AGRF5_MOUSE;
|
| Genbank Protein ID |
NP_001074647.1;
|
| Genbank Nucleotide ID |
NM_001081178.1;
|
| Protein Name |
Adhesion G protein-coupled receptor F5 |
| Protein Synonyms/Alias |
G-protein coupled receptor 116; |
| Gene Name |
Adgrf5 |
| Gene Synonyms/Alias |
Gpr116; |
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
Receptor that plays a critical role in lung surfactant homeostasis (PubMed:23590306, PubMed:23922714, PubMed:23684610). May play a role in controlling adipocyte function (PubMed:22971422).Functional Description
Receptor that plays a critical role in lung surfactant homeostasis (PubMed:23590306, PubMed:23922714, PubMed:23684610). May play a role in controlling adipocyte function (PubMed:22971422). |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MRSPRTFTFY FLLLVICSSE AALSTPTEPI VQPSILQEHE LAGEELLRPK RAAAAGDRVA 60
EEYMVDIEIS FENVSFLESI RAHLNNLSFP IRGTEADILN IAMTTVCTPA GNDLLCFCEK 120
GYQWSEERCL HSLTCQDYDS ALPGGYCSCL KGLPPQGPFC QLPEAFITLK LKVRLNIGFQ 180
EDLKNTSSAL YRSYKTDLER AFRAGYRTLP GFRSVTVTQF TKGSVVVNYV VRVTSAPLPG 240
SIHKANEQVI QNLNHTYKMD YNSFQGTPSN ETKFTVIPEF IFEGDNVTLE CETEFVTSNT 300
SWYYGEKRSD IQNSDKYSIH TTVINNISLI TRLTIYNFTQ HDAGMYGCNV TLDIFEYGTV 360
RKLDVTPIRI LAKEERKVVC DNHPISLNCC SENIANWSSI EWKQEGKISI LGNPESDLES 420
SCSTYTLKAD GTQCPSGSSG TTVIYTCEFV SAYGARGSKN IAVTFTSVAN LTITRDPISV 480
SEGQSFSITC LSDVSSFDEV YWNTSAGIKI HPRFYTMRRY QDGAESVLMV KTSTREWNGT 540
YHCIFRYKNS YSIATKDVTV HPLPLVSDIM MDPLEASGLC TSSHQFKCCV EEDAGEEYAV 600
TFHVDSSSFP AEREVIGKQA CYTYSLPANL PRCPKDIAVF CHFTNAANSS VRSPSMKLKL 660
IPRENVTCQD PIIGIGDPGK VIQKLCQFSG VYGSPGQAIG GTVTYKCVGT QWKEESRACI 720
SAPINGLLQV AKALIKSPTQ DQKLPTYLRD LSVSAGKEEQ DIRSSPGSLG AIISILDLLS 780
TVPTQVNSEM MRDILATINV ILDKSALNSW EKLLQQQSNQ SSQFLHSVER FSQALQLGDS 840
TPPFLAHPNV QMKSMVIKRG HPQIYQQQFI FKDSDLWGDV AIDECQLGNL QPDSSIVTVA 900
FPTLKAILAQ DVQRKTSSNS LVMTTTVSHN IVKPFRISMT FKNNHRSGGK PQCVFWNFSL 960
ANNTGGWDSS GCSVEDDGRD NRDRVFCKCN HLTSFSILMS PDSPDPGSLL KILLDIISYI 1020
GLGFSIVSLA ACLVVEAMVW KSVTKNRTSY MRHICIVNIA FCLLIADIWF IVAGAIHDGR 1080
YPLNETACVA ATFFIHFFYL SVFFWMLTLG LMLFYRLIFI LHDASKSTQK AIAFSLGYGC 1140
PLIISSITVG VTQPQEVYMR KNACWLNWED TRALLAFAIP ALIIVVVNVS ITVVVITKIL 1200
RPSIGDKPGK QEKSSLFQIS KSIGVLTPLL GLTWGFGLAT VIQGSNAVFH IIFTLLNAFQ 1260
GLFILLFGCL WDQKVQEALL HKFSLSRWSS QHSKSTSIGS STPVFSMSSP ISRRFNNLFG 1320
KTGTYNVSTP ETTSSSLENS SSAYSLLN
1349Fasta Sequence
>G5E8Q8|Adgrf5|Mus musculus(Mouse)
MRSPRTFTFYFLLLVICSSEAALSTPTEPIVQPSILQEHELAGEELLRPKRAAAAGDRVAEEYMVDIEISFENVSFLESIRAHLNNLSFPIRGTEADILNIAMTTVCTPAGNDLLCFCEKGYQWSEERCLHSLTCQDYDSALPGGYCSCLKGLPPQGPFCQLPEAFITLKLKVRLNIGFQEDLKNTSSALYRSYKTDLERAFRAGYRTLPGFRSVTVTQFTKGSVVVNYVVRVTSAPLPGSIHKANEQVIQNLNHTYKMDYNSFQGTPSNETKFTVIPEFIFEGDNVTLECETEFVTSNTSWYYGEKRSDIQNSDKYSIHTTVINNISLITRLTIYNFTQHDAGMYGCNVTLDIFEYGTVRKLDVTPIRILAKEERKVVCDNHPISLNCCSENIANWSSIEWKQEGKISILGNPESDLESSCSTYTLKADGTQCPSGSSGTTVIYTCEFVSAYGARGSKNIAVTFTSVANLTITRDPISVSEGQSFSITCLSDVSSFDEVYWNTSAGIKIHPRFYTMRRYQDGAESVLMVKTSTREWNGTYHCIFRYKNSYSIATKDVTVHPLPLVSDIMMDPLEASGLCTSSHQFKCCVEEDAGEEYAVTFHVDSSSFPAEREVIGKQACYTYSLPANLPRCPKDIAVFCHFTNAANSSVRSPSMKLKLIPRENVTCQDPIIGIGDPGKVIQKLCQFSGVYGSPGQAIGGTVTYKCVGTQWKEESRACISAPINGLLQVAKALIKSPTQDQKLPTYLRDLSVSAGKEEQDIRSSPGSLGAIISILDLLSTVPTQVNSEMMRDILATINVILDKSALNSWEKLLQQQSNQSSQFLHSVERFSQALQLGDSTPPFLAHPNVQMKSMVIKRGHPQIYQQQFIFKDSDLWGDVAIDECQLGNLQPDSSIVTVAFPTLKAILAQDVQRKTSSNSLVMTTTVSHNIVKPFRISMTFKNNHRSGGKPQCVFWNFSLANNTGGWDSSGCSVEDDGRDNRDRVFCKCNHLTSFSILMSPDSPDPGSLLKILLDIISYIGLGFSIVSLAACLVVEAMVWKSVTKNRTSYMRHICIVNIAFCLLIADIWFIVAGAIHDGRYPLNETACVAATFFIHFFYLSVFFWMLTLGLMLFYRLIFILHDASKSTQKAIAFSLGYGCPLIISSITVGVTQPQEVYMRKNACWLNWEDTRALLAFAIPALIIVVVNVSITVVVITKILRPSIGDKPGKQEKSSLFQISKSIGVLTPLLGLTWGFGLATVIQGSNAVFHIIFTLLNAFQGLFILLFGCLWDQKVQEALLHKFSLSRWSSQHSKSTSIGSSTPVFSMSSPISRRFNNLFGKTGTYNVSTPETTSSSLENSSSAYSLLN
|
| Keyword |
KW-0068--Autocatalytic cleavage
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0393--Immunoglobulin domain
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
|
| Interpro |
IPR017981--GPCR_2-like
IPR008078--GPCR_2_Ig-hepta-like_rcpt
IPR000832--GPCR_2_secretin-like
IPR017983--GPCR_2_secretin-like_CS
IPR000203--GPS
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR013098--Ig_I-set
IPR003599--Ig_sub
IPR013151--Immunoglobulin
IPR000082--SEA_dom
|
| PROSITE |
PS00650--G_PROTEIN_RECEP_F2_2
PS50261--G_PROTEIN_RECEP_F2_4
PS50221--GPS
PS50835--IG_LIKE
PS50024--SEA
|
| Pfam |
PF00002--7tm_2
PF01825--GPS
PF07679--I-set
PF00047--ig
PF01390--SEA
|
| Gene Ontology |
GO:0045177--C:apical part of cell
GO:0009986--C:cell surface
GO:0031410--C:cytoplasmic vesicle
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0004930--F:G-protein coupled receptor activity
GO:0007166--P:cell surface receptor signaling pathway
GO:0006112--P:energy reserve metabolic process
GO:0045444--P:fat cell differentiation
GO:0042593--P:glucose homeostasis
GO:0043031--P:negative regulation of macrophage activation
GO:0071073--P:positive regulation of phospholipid biosynthetic process
GO:0019216--P:regulation of lipid metabolic process
GO:0043129--P:surfactant homeostasis
|
