dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052423
Uniprot Accession G5E8L8; G5E8L8_MOUSE;
Genbank Protein ID NP_036076.2;
Genbank Nucleotide ID NM_011946.3;
Protein Name Mitogen activated protein kinase kinase kinase 2
Protein Synonyms/Alias
Gene Name Map3k2
Gene Synonyms/Alias mCG_127139;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
163GPPNRDRSSPPPGYIcurated21743459
164PPNRDRSSPPPGYIPPHOSIDA;curated21081558; 18846507
Sequence
(Fasta)		MDDQQALNSI MQDLAVLHKA SRPALSLQET RKAKPSSPKK QNDVRVKFEH RGEKRILQVT 60
RPVKLEDLRS KSKIAFGQSM DLHYTNNELV IPLTTQDDLD KAVELLDRSI HMKSLKILLV 120
VNGSTQATNL EPSPSPEDLN NTPLGAERKK RLSVVGPPNR DRSSPPPGYI PDELHQIARN 180
GSFTSINSEG EFIPESMDQM LDPLSLSSPE NSGSGSCPSL DSPLDGESYP KSRMPRAQSY 240
PDNHQEFTDY DNPIFEKFGK GGTYPRRYHV SYHHQEYNDG RKTFPRARRT QGTSFRSPVS 300
FSPTDHSLST SSGSSVFTPE YDDSRIRRRG SDIDNPTLTV TDISPPSRSP RAPTNWRLGK 360
LLGQGAFGRV YLCYDVDTGR ELAVKQVQFN PESPETSKEV NALECEIQLL KNLLHERIVQ 420
YYGCLRDPQE KTLSIFMEYM PGGSIKDQLK AYGALTENVT RKYTRQILEG VHYLHSNMIV 480
HRDIKGANIL RDSTGNIKLG DFGASKRLQT ICLSGTGMKS VTGTPYWMSP EVISGEGYGR 540
KADIWSVACT VVEMLTEKPP WAEFEAMAAI FKIATQPTNP KLPPHVSDYT RDFLKRIFVE 600
AKLRPSAEEL LRHMFVHYH
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
PROSITE

PS51745--PB1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
Pfam

PF00564--PB1
PF00069--Pkinase
Gene Ontology

GO:0005829--C:cytosol
GO:0005622--C:intracellular
GO:0005654--C:nucleoplasm
GO:0005524--F:ATP binding
GO:0004708--F:MAP kinase kinase activity
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0071260--P:cellular response to mechanical stimulus
GO:0000165--P:MAPK cascade
GO:0045893--P:positive regulation of transcription, DNA-templated