dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052418
Uniprot Accession G5E8J4; G5E8J4_MOUSE;
Genbank Protein ID NP_001139671.1; NP_036007.2;
Genbank Nucleotide ID NM_001146199.1; NM_011877.2;
Protein Name Protein tyrosine phosphatase, non-receptor type 21, isoform CRA_a
Protein Synonyms/Alias
Gene Name Ptpn21
Gene Synonyms/Alias mCG_22432;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
705KKSLSDATMLIHSSEcurated21183079
710DATMLIHSSEEDEDLcurated21183079
711ATMLIHSSEEDEDLEcurated21183079
Sequence
(Fasta)
MPLPFGLKLK RTRRYTVSSK SCLVARIQLL NNEFVEFTLS VESTGQESLE AVAQRLELRE 60
VTYFSLWYYN KQNQRRWVDL EKPLKKQLDK HALEPTVYFG VLFYVPSVSQ LQQEITRYQY 120
YLQLKKDILE GNLPCTLEHA IQLAGLAVQA DFGDFDQYES QDFLQKFALL PVAWLQDEKV 180
LEEAAQKVAL LHQKYRGLTA PEAELLYMQE VERMDGYGEE SYPAKDSQGS DISIGACLDG 240
IFVKHKNGRP PVVFRWHDIA NMSHNKSFFA LELANKEETI QFQTEDMETA KYVWRLCVAR 300
HKFYRLNQCS LQTQAATLNS VRRGSSSRMS LPKPQPYAMP PPPQLHYNGH YTEPFASSQD 360
NIFVPNKNGF YCHSQTSLDR TQIDLSGRIR NGSVYSAHST NSLNTLQPYL QPSPMSSNPS 420
ITGSDVMRPD YIPSHRHSAL IPPSYRPTPD YETVMKQLNR GMVHADRHSH SLRNLNIGSS 480
YAYSRPDALV YSQPEIREHP HLTSPQSAHY PFNLNYSFHS QSPYPYPAER RPVVGAVSVP 540
ELTNVQLQAQ DYPAPNIMRT QVYRPPPPYP YPRPANSTPD LSRHLYISSS NPDLITRRVH 600
HSVQTFQEDS LPVAHSLQEV SEPLTAARHA HLQKRNSIEI AGLTHGFEGL RLKERTVSAS 660
AADVAPRTFS AGSQSSVFSD KMKQEGTEEQ EGGRYSHKKS LSDATMLIHS SEEDEDLEED 720
SSREQAISAV SEPRLTAAFS QELNYPCASA TPITGPLHIF EPKPHVTEPE KRAKDISPVH 780
LVVETHRPRR DGLLTPSMSE SDLTTSGRYR ARRDSVKKRP VSDLLSGKKS AVEGLPPLGG 840
MKKTRADAKK IGPLKLAALN GLSLSRLPLP DEGKEVSTRA TNDERCKVLE QRLEQGMVFT 900
EYERILKKRL VDGECSTARL PENAERNRFQ DVLPYDDARV ELVPTKENNT GYINASHIKV 960
SVSGIEWDYI ATQGPLQNTC QDFWQMVWEQ GVAIIAMVTA EEEGGREKSF RYWPRLGSRH 1020
NTVTYGRFKI TTRFRTDSGC YATTGLKMKH LLTGQERTVW HLQYTDWPEH GCPEDLKGFL 1080
SYLEEIQSVR RHTNSTSEPK SHNPPLLVHC SAGVGRTGVV ILSEIMVACL EHNEVLDIPR 1140
VLDMLRQQRM MLVQTLGQYT FVYRVLIQFL KSSRLI 1177
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0904--Protein phosphatase
KW-1267--Proteomics identification
KW-0675--Receptor
KW-1185--Reference proteome

Interpro

IPR019749--Band_41_domain
IPR014352--FERM/acyl-CoA-bd_prot_3-hlx
IPR019748--FERM_central
IPR019747--FERM_CS
IPR000299--FERM_domain
IPR018979--FERM_N
IPR018980--FERM_PH-like_C
IPR011993--PH/PTB_dom
IPR029021--Prot-tyrosine_phosphatase-like
IPR000242--PTPase_domain
IPR016130--Tyr_Pase_AS
IPR014392--Tyr_Pase_non-rcpt_typ-14/21
IPR000387--TYR_PHOSPHATASE_dom
IPR029071--Ubiquitin-rel_dom

PROSITE

PS00660--FERM_1
PS00661--FERM_2
PS50057--FERM_3
PS00383--TYR_PHOSPHATASE_1
PS50056--TYR_PHOSPHATASE_2
PS50055--TYR_PHOSPHATASE_PTP

Pfam

PF09380--FERM_C
PF00373--FERM_M
PF09379--FERM_N
PF00102--Y_phosphatase

Gene Ontology

GO:0005856--C:cytoskeleton
GO:0004725--F:protein tyrosine phosphatase activity