dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052373
Uniprot Accession G3XA35; G3XA35_MOUSE;
Genbank Protein ID NP_062262.2;
Genbank Nucleotide ID NM_019389.2;
Protein Name MCG116562, isoform CRA_a
Protein Synonyms/Alias
Gene Name Vcan
Gene Synonyms/Alias mCG_116562;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
1321HERMEDVSNEVRMLIPHOSIDA;curated21081558; 22817900; 21183079
Sequence
(Fasta)		MLINMKGILW MCSTLLLTHA LHQAKMETSP PVKGSLSGKV VLPCHFSTLP TLPPNYNTSE 60
FLRIKWSKME VDKNGKDIKE TTVLVAQNGN IKIGQDYKGR VSVPTHPDDV GDASLTMVKL 120
RASDAGVYRC DVMYGIEDTQ DTMSLAVDGV VFHYRAATSR YTLNFAAAQQ ACLDIGAVIA 180
SPEQLFAAYE DGFEQCDAGW LSDQTVRYPI RAPREGCYGD MMGKEGVRTY GFRSPQETYD 240
VYCYVDHLDG DVFHITAPSK FTFEEAEAEC TSRDARLATV GELQAAWRNG FDQCDYGWLS 300
DASVRHPVTV ARAQCGGGLL GVRTLYRFEN QTCFPLPDSR FDAYCFKRRL SDMIVSGHPI 360
DSESKEEEPC SEETDPLHDL FAEILPELPD SFEIDIYHSE EDEDGEEDCV NATDVTTTPS 420
VQYINGKQLV TTVPKDPEAA EARRGQYESV APSQNFPDSS ATDTHQFILA ETESSTTMQF 480
KKSKEGTELL EITWKPETYP ETPDHVSSGE PDVFPTLSSH DGKTTRWSES ITESSPNLEN 540
PVHKQPKPVP LFPEESSGEG AIEQASQETI LSRATEVALG KETDQSPTLS TSSILSSSVS 600
VNVLEEEPLT LTGISQTDES MSTIESWVEI TPSQTVKFSE SSSAPIIEGS GEVEENKNKI 660
FNMVTDLPQR DPTDTLSPLD MSKIMITNHH IYIPATTAPL DSKLPSPDAR PTQFGIQTAT 720
SEWVSDKSFE GRKREEDEEG AVNAAHQGEV RAATERSDHL LLTPELESSN VDASSDLATW 780
EGFILETTPT ESEKEMANST PVFRETIGVA NVEAQPFEHS SSSHPRVQEE LTTLSGNPPS 840
LFTDLGSGDA STGMELITAS LFTLDLESET KVKKELPSTP SPSVEISSSF EPTGLTPSTV 900
LDIEIAGVMS QTSQKTLISE ISGKPTSQSG VRDLYTGFPM GEDFSGDFSE YPTVSYPTMK 960
EETVGMGGSD DERVRDTQTS SSIPTTSDNI YPVPDSKGPD STVASTTAFP WEEVMSSAEG 1020
SGEQLASVRS SVGPVLPLAV DIFSGTESPY FDEEFEEVAA VTEANERPTV LPTAASGNTV 1080
DLTENGYIEV NSTMSLDFPQ TMEPSKLWSK PEVNLDKQEI GRETVTKEKA QGQKTFESLH 1140
SSFAPEQTIL ETQSLIETEF QTSDYSMLTT LKTYITNKEV EEEGMSIAHM STPGPGIKDL 1200
ESYTTHPEAP GKSHSFSATA LVTESGAARS VLMDSSTQEE ESIKLFQKGV KLTNKESNAD 1260
LSFSGLGSGE ALPPLPTTSV NLTDMKQIIS TLYAETSHME SLGTSILGDK MEDHERMEDV 1320
SNEVRMLISK TGSISQDSTE ALDTTLSHTG TEEPTTSTLP FVKLMDLERS PKQTLRWEEE 1380
TQTHRPQTMS GLISNENSSA SEAEEAATSP TAFLPQTYSV EMTKHFAPSE SQPSDLFNVN 1440
SGEGSGEVDT LDLVYTSGTT QASSQGDSML ASHGFLEKHP EVSKTEAGAT DVSPTASAMF 1500
LHHSEYKSSL YPTSTLPSTE PYKSPSEGIE DGLQDNIQFE GSTLKPSRRK TTESIIIDLD 1560
KEDSKDLGLT ITESAIVEIL PELTSDKNII IDIDHTKPVY EYIPGIQTDL DPEIKLESHG 1620
SSEESLQVQE KYEGAVTLSP TEESFEGSGD ALLAGYTQAI YNESVTPNDG KQAEDISFSF 1680
ATGIPVSSTE TELHTFFPTA STLHIPSKLT TASPEIDKPN IEAISLDDIF ESSTLSDGQA 1740
IADQSEVIST LGHLEKTQEE YEEKKYGGPS FQPEFFSGVG EVLTDPPAYV SIGSTYLIAQ 1800
TLTELPNVVR PSDSTHYTEA TPEVSSLAEL SPQIPSSPFP VYVDNGVSKF PEVPHTSAQP 1860
VSTVTSSQKS IESPFKEVHA NIEETIKPLG GNVHRTEPPS MSRDPALDVS EDESKHKLLE 1920
ELETSPTKPE TSQDFPNKAK DHIPGETVGM LAGIRTTESE PVITADDMEL GGATQQPHSA 1980
SAAFRVETGM VPQPIQQEPE RPTFPSLEIN HETHTSLFGE SILATSEKQV SQKILDNSNQ 2040
ATVSSTLDLH TAHALSPFSI LDNSNETAFL IGISEESVEG TAVYLPGPDL CKTNPCLNGG 2100
TCYPTETSYV CTCAPGYSGD QCELDFDECH SNPCRNGATC VDGFNTFRCL CLPSYVGALC 2160
EQDTETCDYG WHKFQGQCYK YFAHRRTWDA AERECRLQGA HLTSILSHEE QMFVNRVGHD 2220
YQWIGLNDKM FEHDFRWTDG SALQYENWRP NQPDSFFSAG EDCVVIIWHE NGQWNDVPCN 2280
YHLTYTCKKG TVACGQPPVV ENAKTFGKMK PRYEINSLIR YHCKDGFIQR HLPTIRCLGN 2340
GRWAMPKITC MNPSAYQRTY SKKYLKNSSS AKDNSINTSK HEHRWSRRRQ ETRR 2395
Keyword

KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0245--EGF-like domain
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0768--Sushi
Interpro

IPR001304--C-type_lectin
IPR016186--C-type_lectin-like
IPR018378--C-type_lectin_CS
IPR016187--C-type_lectin_fold
IPR001881--EGF-like_Ca-bd_dom
IPR013032--EGF-like_CS
IPR000742--EGF-like_dom
IPR000152--EGF-type_Asp/Asn_hydroxyl_site
IPR018097--EGF_Ca-bd_CS
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR003599--Ig_sub
IPR013106--Ig_V-set
IPR000538--Link_dom
IPR000436--Sushi_SCR_CCP_dom
PROSITE

PS00010--ASX_HYDROXYL
PS00615--C_TYPE_LECTIN_1
PS50041--C_TYPE_LECTIN_2
PS00022--EGF_1
PS01186--EGF_2
PS50026--EGF_3
PS01187--EGF_CA
PS50835--IG_LIKE
PS01241--LINK_1
PS50963--LINK_2
PS50923--SUSHI
Pfam

PF00008--EGF
PF00059--Lectin_C
PF00084--Sushi
PF07686--V-set
PF00193--Xlink
Gene Ontology

GO:0031012--C:extracellular matrix
GO:0005576--C:extracellular region
GO:0005615--C:extracellular space
GO:0043231--C:intracellular membrane-bounded organelle
GO:0016020--C:membrane
GO:0005578--C:proteinaceous extracellular matrix
GO:0005509--F:calcium ion binding
GO:0005540--F:hyaluronic acid binding
GO:0019903--F:protein phosphatase binding
GO:0007155--P:cell adhesion
GO:0007417--P:central nervous system development
GO:0008347--P:glial cell migration
GO:0007507--P:heart development
GO:0001649--P:osteoblast differentiation
GO:0043666--P:regulation of phosphoprotein phosphatase activity
GO:0001501--P:skeletal system development