dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052354
Uniprot Accession G3X9J0; G3X9J0_MOUSE;
Genbank Protein ID NP_001074497.1; XP_011249034.1;
Genbank Nucleotide ID NM_001081028.1; XM_011250732.1;
Protein Name MCG122846
Protein Synonyms/Alias
Gene Name Sipa1l3
Gene Synonyms/Alias mCG_122846;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 50 (View all)
PositionPeptidesSourceReferences ( PMIDs )
91RDALREQSNPSPSQDPhosphoSitePlus22135298
94LREQSNPSPSQDTDGPhosphoSitePlus;curated22135298; 22817900; 21183079; 25338131
96EQSNPSPSQDTDGVKcurated23684622
140HRLSRRRSKDVEFQDPhosphoSitePlus;curated22135298; 23684622; 22817900; 21183079; 25338131
152FQDGWPRSPGRAFLPPhosphoSitePlus;curated22135298; 23684622; 25338131
164FLPLRHRSSSEITLScurated21183079; 24723360
165LPLRHRSSSEITLSEPhosphoSitePlus;curated22135298; 25338131
166PLRHRSSSEITLSECPhosphoSitePlus;curated22135298; 25338131
169HRSSSEITLSECDVEPhosphoSitePlus;curated22135298; 22817900; 21183079
198PLFREYGSTSSIDVQPhosphoSitePlus22135298
201REYGSTSSIDVQGVPPhosphoSitePlus22135298
286KPVRGLGSGDTVDSScurated25338131
384LTASRAHSLGTLDPAcurated25338131
394TLDPAFTSTEDLNCKPhosphoSitePlus;curated22135298; 25338131
444FSRASVGSPGGSSEAPhosphoSitePlus;curated22135298; 25338131
487QSRPRQYSIEHVDLGcurated25338131
1129LHSKRPVSFPETPFAcurated25338131
1154PYRQPSGSFSTPGSAcurated25338131
1163STPGSATYARYKPSPPhosphoSitePlus22135298
1208GLTSQESTMERPKPEPhosphoSitePlus22135298
Sequence
(Fasta)
MTTYRPLPND GVDLAASCGA RSTDILPGPH PGDYTPMGFW AQNGSMPQPL GESPAATTTR 60
PSPTTPAMPK MGVRARVADW PPKRDALREQ SNPSPSQDTD GVKTTKVAHS MRNLQNGQLP 120
SSTPASSGSR AFHRLSRRRS KDVEFQDGWP RSPGRAFLPL RHRSSSEITL SECDVEEPGD 180
PRGTRHPGVL PLFREYGSTS SIDVQGVPEQ SFFDILNEFR SEQPEARGSQ NLRELLQVDP 240
GALSGGSCGT KGDPRNGQPT KDSLQSLQPL KEKEKSRKKP VRGLGSGDTV DSSIFRKLRS 300
SKPEGEVGRP LGETEESRSP PEASRPWVCQ KSFAHFDVQS MLFDLNEAAA NRVSVAQRRN 360
TTTGASAASA ASAMVTLTAS RAHSLGTLDP AFTSTEDLNC KENLEQDLGD DNSNDLLLSC 420
PHFRNEIGGE RERNVSFSRA SVGSPGGSSE AHMAEPTLST HRTNASISVL EVPKEQQRTQ 480
SRPRQYSIEH VDLGARYYQD YFVGKEHANY FGVDEKLGPV AVSIKREKLE DHKDHGPQYQ 540
YRIIFRTREL ITLRGSILED ATPTATKHGT GRGLPLKDAL EYVIPELNIH CLRLALNTPK 600
VTEQLLKLDE QGLCRKHKVG ILYCKAGQSS EEEMYNNEEA GPAFEEFLDL LGDKVCLKGF 660
TKYAAQLDVK TDSTGTHSLY TTYQDYEIMF HVSTLLPYTP NNRQQLLRKR HIGNDIVTII 720
FQEPGALPFT PKNIRSHFQH VFIIVRVHNP CTENVCYSMA VTRSKDAPPF GPPIPNGTTF 780
RKSDVFRDFL LAKVINAENA AHKSDKFHTM ATRTRQEYLK DLAENCVSNT PIDSSGKFNL 840
ISLTSKKKEK TKARAGAEQH SAGAIAWRVA AQDYAQGSEI DCILGISNEF VVLLDLRTKE 900
VVFNCYCGDV IGWTPDSSTI KIFYGRGDHI FLQAAEGSVE DIRDIVQRLK VMTNGWETVD 960
MTLRRNGLGQ LGFHVKYDGT VAEVEDYGFA WQAGLRQGSR LVEICKVAVV TLSHDQMIDL 1020
LRTSVTVKVV IIPPFEDGTP RRGWPETYDM NASEPKTESE TTTPGGRPPY RSNAPWQWSG 1080
PASHNSLPAT KWTTPATPGH AQSLSRLPKQ TPVVPFRESQ PLHSKRPVSF PETPFAASPA 1140
GADRVPPYRQ PSGSFSTPGS ATYARYKPSP ERYAAAPHPL LSFDPHFMHD GMSSGDSSSG 1200
GLTSQESTME RPKPEPLWHV PAQARLSAMT GSIGSKHPSR QDAAGKDSPN RHSKGEPQYS 1260
SHSSSNTLSS NASSSHSDDR WFDPLDPLEP EQDPFSKGGS SDSGIDTTLY TSSPSCMSLA 1320
KAPRPTKPHK PPGNIGLCGG GRESAGRPHP VDRRREVSPA PVVAGQNKGY RPKLYSSGSC 1380
TPPGLVGGSR DPPRQPSDMG SRAGYPTQVY KTASAETPRP SQLSQCSPFQ LSTSVPKSFF 1440
SKQPAHNKHS TGWKRTDEPP PRPLPFTDSK KQVDTNAKNV FGQPRLRASL RDLRSPRKNY 1500
KSTIEDDLKK LIVMDNLGPE QERDTGQSPQ KSLQRTLSDE SLCSGRREPS FASPASLEPG 1560
LPSDVLFTST CTFPSSTLPA RRQHQHAHPP SGAPSTTPAT GNGFPEKKSA ISASELSLAD 1620
GRDRPLRRLD PGMMPLPDTA AGLEWSSLVN AAKAYEVQRA VSLFSLNDPA LSPEIPPAHS 1680
PVHSHLSLER GPQTPRATPT MSEESPLDLT GKVYQLEVML KQLHTDLQKE KQDKVVLQSE 1740
VASLRQNNQR LQEESQAASE QLRKFAELFS REKKEL 1777
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001478--PDZ
IPR000331--Rap_GAP_dom
IPR031204--SIPA1L3
IPR021818--SIPA1L_C

PROSITE

PS50106--PDZ
PS50085--RAPGAP

Pfam

PF02145--Rap_GAP
PF11881--SPAR_C

Gene Ontology

GO:0005615--C:extracellular space
GO:0005096--F:GTPase activator activity
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0051056--P:regulation of small GTPase mediated signal transduction