| Tag |
Content |
| dbPAF ID |
dbPAF-0052351 |
| Uniprot Accession |
G3X9G2; G3X9G2_MOUSE;
|
| Genbank Protein ID |
NP_001039429.1;
|
| Genbank Nucleotide ID |
NM_001045964.1;
|
| Protein Name |
Misshapen-like kinase 1 |
| Protein Synonyms/Alias |
|
| Gene Name |
Mink1 |
| Gene Synonyms/Alias |
mCG_134369; |
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 4 |
Sequence
(Fasta) | MGDPAPARSL DDIDLSALRD PAGIFELVEV VGNGTYGQVY KGRHVKTGQL AAIKVMDVTE 60
DEEEEIKQEI NMLKKYSHHR NIATYYGAFI KKSPPGNDDQ LWLVMEFCGA GSVTDLVKNT 120
KGNALKEDCI AYICREILRG LAHLHAHKVI HRDIKGQNVL LTENAEVKLV DFGVSAQLDR 180
TVGRRNTFIG TPYWMAPEVI ACDENPDATY DYRSDIWSLG ITAIEMAEGA PPLCDMHPMR 240
ALFLIPRNPP PRLKSKKWSK KFTDFIDTCL IKTYLSRPPT EQLLKFPFIR DQPTERQVRI 300
QLKDHIDRSR KKRGEKEETE YEYSGSEEED DSHGEEGEPS SIMNVPGEST LRREFLRLQQ 360
ENKSNSEALK QQQQLQQQQQ RDPEAHIKHL LHQRQRRIEE QKEERRRVEE QQRREREQRK 420
LQEKEQQRRL EDMQALRREE ERRQAEREQE YKRKQLEEQR QSERLQRQLQ QEHAYLKSLQ 480
QQQQQQQLQK QQQQQQQILP GDRKPLYHYG RGINPADKPA WAREVEERAR MNKQQNSPLA 540
KAKPSSAGPE PPISQASPSP PGPLSQTPPM QRPVEPQEGP HKSLVAHRVP LKPYAAPVPR 600
SQSLQDQPTR NLAAFPASHD PDPAAVPTPT ATPSARGAVI RQNSDPTSEG PGPSPNPPSW 660
VRPDNEAPPK VPQRTSSIAT ALNTSGAGGS RPAQAVRARP RSNSAWQIYL QRRAERGTPK 720
PPGPPAQPPG PPNASSNPDL RRSDPGWERS DSVLPASHGH LPQAGSLERN RNRVGASTKL 780
DSSPVLSPGN KAKPEDHRSR PGRPASYKRA IGEDFVLLKE RTLDEAPKPP KKAMDYSSSS 840
EEVESSEEEE EEGDGEPSEG SRDTPGGRDG DTDSVSTMVV HDVEEISGTQ PSYGGGTMVV 900
QRTPEEERSL LLADSNGYTN LPDVVQPSHS PTENSKGQSP PTKDGGSDYQ SRGLVKAPGK 960
SSFTMFVDLG IYQPGGSGDT IPITALVGGE GGRLDQLQFD VRKGSVVNVN PTNTRAHSET 1020
PEIRKYKKRF NSEILCAALW GVNLLVGTEN GLMLLDRSGQ GKVYGLIGRR RFQQMDVLEG 1080
LNLLITISGK RNKLRVYYLS WLRNKILHND PEVEKKQGWT TVGDMEGCGH YRVVKYERIK 1140
FLVIALKNSV EVYAWAPKPY HKFMAFKSFA DLPHRPLLVD LTVEEGQRLK VIYGSSAGFH 1200
AVDVDSGNSY DIYIPVHIQS QITPHAIIFL PNTDGMEMLL CYEDEGVYVN TYGRIIKDVV 1260
LQWGEMPTSV AYICSNQIMG WGEKAIEIRS VETGHLDGVF MHKRAQRLKF LCERNDKVFF 1320
ASVRSGGSSQ VYFMTLNRNC IMNW
1345Fasta Sequence
>G3X9G2|Mink1|Mus musculus(Mouse)
MGDPAPARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFTDFIDTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQQQILPGDRKPLYHYGRGINPADKPAWAREVEERARMNKQQNSPLAKAKPSSAGPEPPISQASPSPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAAVPTPTATPSARGAVIRQNSDPTSEGPGPSPNPPSWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRARPRSNSAWQIYLQRRAERGTPKPPGPPAQPPGPPNASSNPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRNRVGASTKLDSSPVLSPGNKAKPEDHRSRPGRPASYKRAIGEDFVLLKERTLDEAPKPPKKAMDYSSSSEEVESSEEEEEEGDGEPSEGSRDTPGGRDGDTDSVSTMVVHDVEEISGTQPSYGGGTMVVQRTPEEERSLLLADSNGYTNLPDVVQPSHSPTENSKGQSPPTKDGGSDYQSRGLVKAPGKSSFTMFVDLGIYQPGGSGDTIPITALVGGEGGRLDQLQFDVRKGSVVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKNSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW
|
| Keyword |
KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
|
| Interpro |
IPR001180--CNH_dom
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
|
| PROSITE |
PS50219--CNH
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
|
| Pfam |
PF00780--CNH
PF00069--Pkinase
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005794--C:Golgi apparatus
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0031532--P:actin cytoskeleton reorganization
GO:0032147--P:activation of protein kinase activity
GO:0000165--P:MAPK cascade
GO:0045060--P:negative thymic T cell selection
GO:0048812--P:neuron projection morphogenesis
GO:0046330--P:positive regulation of JNK cascade
GO:0046777--P:protein autophosphorylation
GO:0006468--P:protein phosphorylation
GO:0042981--P:regulation of apoptotic process
GO:0030334--P:regulation of cell migration
GO:0022407--P:regulation of cell-cell adhesion
GO:0001952--P:regulation of cell-matrix adhesion
GO:0007346--P:regulation of mitotic cell cycle
GO:0031098--P:stress-activated protein kinase signaling cascade
|
