dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052339
Uniprot Accession G3X963; G3X963_MOUSE;
Genbank Protein ID NP_081711.2;
Genbank Nucleotide ID NM_027435.2;
Protein Name ATPase family AAA domain-containing protein 2
Protein Synonyms/Alias
Gene Name Atad2
Gene Synonyms/Alias mCG_7707;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 13
PositionPeptidesSourceReferences ( PMIDs )
26ATDSLDLSSEFLSLQPhosphoSitePlus22135298
147AEHLHEQSGDVEVRRPhosphoSitePlus22135298
162SCRIRSRYSTMNQSVPhosphoSitePlus;curated22135298; 21183079
168RYSTMNQSVLFDKLIPhosphoSitePlus;curated22135298; 22817900; 21183079
286KTTVYYQSPLESKPRPhosphoSitePlus;curated22135298; 22817900; 21183079
290YYQSPLESKPRHQRKPhosphoSitePlus;curated22135298; 22817900; 21183079
303RKPNMFYSGPASPARPhosphoSitePlus22135298
307MFYSGPASPARPRFRPhosphoSitePlus;curated22135298; 23684622; 22817900; 21183079
316ARPRFRLSSTGPRSPPhosphoSitePlus22135298
317RPRFRLSSTGPRSPYPhosphoSitePlus;curated22135298; 21743459; 22817900; 21183079
318PRFRLSSTGPRSPYCPhosphoSitePlus22135298
322LSSTGPRSPYCKRMSPhosphoSitePlus;curated22135298; 21743459; 22817900; 21183079
324STGPRSPYCKRMSRRPhosphoSitePlus22135298
Sequence
(Fasta)		MVVLRSSLEL HSRSTTSSAT DSLDLSSEFL SLQDSGGRRP RLRRAGRKST ASKAAGDGFT 60
VKGAETYHNT RSLRSLRNQA QTSSESSFDK NVDRTEKYSN GRHFTRQFAR QQADKKEECK 120
EDKVIPVIRS LRNRNIAPTA EHLHEQSGDV EVRRSCRIRS RYSTMNQSVL FDKLITNTAE 180
AVLQKMDDMK KMRRQRMKKL EDLGVFNETE ESNLTMYTRG KLKAIQRADE ETTDNQDGSV 240
ESSEEGEEQE DDDGEDEDDE DEEEGEEDNQ KRYYLRQRKT TVYYQSPLES KPRHQRKPNM 300
FYSGPASPAR PRFRLSSTGP RSPYCKRMSR RRHAIHSSDS TSSSSSEDDC FERRTKRNRN 360
RAINRCLPLN FRKDEIRGIY KDRMKIGASL ADVDPMQLDT SVRFDSVGGL SSHIAALKEM 420
VVFPLLYPEV FEKFKIQPPR GCLFYGPPGT GKTLVARALA NECSRGDKRV AFFMRKGADC 480
LSKWVGESER QLRLLFDQAY QMRPAIIFFD EIDGLAPVRS SRQDQIHSSI VSTLLALMDG 540
LDSRGEIVVI GATNRLDSID PALRRPGRFD REFLFSLPDK NARKEILKIH TRDWNPKPVD 600
MFLEELAEHC VGYCGADIKS ICAEAALCAL RRRYPQIYTT SEKLQLDLSS ITISAKDFEA 660
ALQKIRPASQ RAVTSPGQAL SAIVKPLLQN TVHRILDALQ KVFPHVEVGT NKSLNSDVSC 720
PFLESDLAYS DDDTPSVYEN GLSQKENLNF LHLNRNACYQ PMSFRPRLLI VGEPGFGQSS 780
HLAPAVIHAL EKFTVYTLDI PVLFGISTTS PEEACSQMIR EAKRTAPSIV YVPHIHLWWE 840
IVGPTLKATF TTLLQTIPSF APVLLLATSE KPYSALPEEV QELFTHDYGE IFNVQLPDKE 900
ERTKFFEDLI LKQASKPPVS QKKAVLQALE VLPVAPPPEP RPLTAEEVKR LEEQEEDTFR 960
ELRIFLRNVT HRLAIDKRFR VFTKPVDPDE VPDYVTVIKQ PMDLSSVISK IDLHKYLTVK 1020
DYLKDIDLIC SNALEYNPDR DPGDRLIRHR ACALRDTAYA IIKEELDEDF EQLCEEIQES 1080
RKKRGCSSSK YAPSYYHVMP KQNSPPVGDK KPDQEQNEKL KVPCTPVACS TPAQLKRKFH 1140
KKSKWHVGTK IKRRKISQAK DNSLNAMNSS SRSDTEDSQH THAEHTEPGN TDESSVEESD 1200
KQNRLESNID LKNNSSSSNI ENELEEPKET TEGTELRKDR IVCRGDASAS QVTDIPEDSE 1260
SKEMDFLRMT LARGSQVEQQ ELISMEQALA ILSQPTPSLV LDHKQLTNIL KTVVKKSQKY 1320
NIFQLENLYA VISQCIYEHR RDYDKTALVQ KMEQAVENFN CSRS 1365
Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR003593--AAA+_ATPase
IPR031252--ANCCA
IPR003959--ATPase_AAA_core
IPR003960--ATPase_AAA_CS
IPR001487--Bromodomain
IPR027417--P-loop_NTPase
PROSITE

PS00674--AAA
PS50014--BROMODOMAIN_2
Pfam

PF00004--AAA
PF00439--Bromodomain
Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003682--F:chromatin binding
GO:0042393--F:histone binding
GO:0031936--P:negative regulation of chromatin silencing
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated