dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052303
Uniprot Accession G3V9M6; G3V9M6_RAT;
Genbank Protein ID XP_006234997.1; XP_008760424.1; XP_008760425.1;
Genbank Nucleotide ID XM_006234935.2; XM_008762202.1; XM_008762203.1;
Protein Name Fibrillin 1, isoform CRA_a
Protein Synonyms/Alias
Gene Name Fbn1
Gene Synonyms/Alias rCG_27283;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
753TYKCICNSGYEVDITcurated22276854
755KCICNSGYEVDITGKcurated22276854
1051KCRNTIGSFKCRCDSPhosphoSitePlus22135298
2703GGPEPPASGEMDDNSPhosphoSitePlus;curated22135298; 23712012; 21630457
2710SGEMDDNSLSPEACYcurated23712012; 21630457
Sequence
(Fasta)
MRRGGLLEVA LAFTLLLESY TSHGADANLE AGSLKETRAN RAKRRGGGGH DALKGPNVCG 60
SRYNAYCCPG WKTLPGGNQC IVPICRHSCG DGFCSRPNMC TCPSGQISPS CGSRSIQHCS 120
IRCMNGGSCS DDHCLCQKGY IGTHCGQPVC ESGCLNGGRC VAPNRCACTY GFTGPQCERD 180
YRTGPCFTVV SNQMCQGQLS GIVCTKTLCC ATVGRAWGHP CEMCPAQPHP CRRGFIPNIR 240
TGACQDVDEC QAIPGLCQGG NCINTVGSFE CKCPAGHKFN EVSQKCEDID ECSTIPGVCD 300
GGECTNTVSS YFCKCPPGFY TSPDGTRCVD VRPGYCYTTL TNGRCSNQLP QSITKMQCCC 360
DVGRCWSPGV TVAPEMCPIR STEDFNKLCS VPLVIPGRPD YPPPPLGPLP PVQPVPGFPS 420
GPVIPVPRPP PEYPYPSPSR EPPKVLPFNV TDYCQLVRYL CQNGRCIPTP GSYRCECNKG 480
FQLDIRGECI DVDECEKNPC TGGECINNQG SYTCHCRAGY QSTLTRTECR DIDECLQNGR 540
ICNNGRCINT DGSFHCVCNA GFHVTRDGKN CEDMDECSIR NMCLNGMCIN EDGSFKCICK 600
PGFQLASDGR YCKDINECET PGICMNGRCV NTDGSYRCEC FPGLAVGLDG RVCVDTHMRS 660
TCYGGYRRGQ CVKPLFGAVT KSECCCASTE YAFGEPCQPC PAQNSAEYQA LCSSGPGMTS 720
AGSDINECAL DPDICPNGIC ENLRGTYKCI CNSGYEVDIT GKNCVDINEC VLNSLLCDNG 780
QCRNTPGSFV CTCPKGFVYK PDLKTCEDID ECESSPCING VCKNSPGSFI CECSPESTLD 840
PTKTICIETI KGTCWQTVID GRCEININGA TLKSECCSSL GAAWGSPCTI CQVDPICGKG 900
YSRIKGTQCE DINECEVFPG VCKNGLCVNS RGSFKCECPS GMTLDATGRI CLDIRLETCF 960
LKYDDEECTL PIAGRHRMDA CCCSVGAAWG TEECEECPLR NSREYEELCP RGPGFATKDI 1020
TNGKPFFKDI NECKMIPSLC THGKCRNTIG SFKCRCDSGF ALDSEERNCT DIDECRISPD 1080
LCGRGQCVNT PGDFECKCDE GYESGFMMMK NCMDIDECQR DPLLCRGGIC HNTEGSYRCE 1140
CPSGHQLSPN ISACIDINEC ELSANLCPSG RCVNLIGKYQ CACNPGYHPT HDRLFCVDID 1200
ECSIMNGGCE TFCTNSDGSY ECSCQPGFAL MPDQRSCTDI DECEDNPNIC DGGQCTNIPG 1260
EYRCLCYDGF MASEDMKTCV DVNECDLNPN ICLSGTCENT KGSFICHCDM GYSGKKGKTG 1320
CTDINECEIG AHNCGRHAVC TNTAGSFKCS CSPGWIGDGI KCTDLDECSN GTHMCSQHAD 1380
CKNTMGSYRC LCKDGYTGDG FTCTDLDECS ENLNLCGNGQ CLNAPGGYRC ECDMGFVPSA 1440
DGKACEDINE CSLPNICVFG TCHNLPGLFR CECEIGYELD RSGGNCTDVN ECLDPTTCIS 1500
GNCVNTPGSY TCDCPPDFEL NPTRVGCVDT RSGNCYLDIR PRGDNGDTAC SNEIGVGVSK 1560
ASCCCSLGKA WGTPCELCPP VNTSEYKILC PGGEGFRPNP ITVILEDIDE CQELPGLCQG 1620
GKCINTFGSF QCRCPTGYYL NEDTRVCDDV NECETPGICG PGTCYNTVGN YTCICPPDYM 1680
QVNGGNNCMD MRRSLCYRNY HADNQTCDGE LLFNMTKKMC CCSYNIGRAW NKPCEQCPIP 1740
STDEFATLCG SQRPGFVIDI YTGLPVDIDE CREIPGVCEN GVCINMVGSF RCECPVGFFY 1800
NDKLLVCEDI DECQNGPVCQ RNAECINTAG SYRCDCKPGY RLTSTGQCND RNECQEIPNI 1860
CSHGQCIDTV GSFYCLCHTG FKTNADQTMC LDINECERDA CGNGTCRNTI GSFNCRCNHG 1920
FILSHNNDCI DVDECATGNG NLCRNGQCVN TVGSFQCRCN EGYEVAPDGR TCVDINECVL 1980
DPGKCAPGTC QNLDGSYRCI CPPGYSLQND KCEDIDECVE EPEICALGTC SNTEGSFKCL 2040
CPEGFSLSST GRRCQDLRMS YCYAKFEGGK CSSPKSRNHS KQECCCALKG EGWGDPCELC 2100
PTEPDEAFRQ ICPFGSGIIV GPDDSAVDMD ECKEPDVCKH GQCINTDGSY RCECPFGYIL 2160
EGNECVDTDE CSVGNPCGNG TCKNVIGGFE CTCEEGFEPG PMMTCEDINE CAQNPLLCAF 2220
RCVNTYGSYE CKCPVGYVLR EDRRMCKDED ECAEGKHDCT EKQMECKNLI GTYMCICGPG 2280
YQRRPDGEGC IDENECQTKP GICENGRCLN TLGSYTCECN DGFTASPTQD ECLDNREGYC 2340
FSEVLQNMCQ IGSSNRNPVT KSECCCDGGR GWGPHCEICP FEGTVAYKKL CPHGRGFMTN 2400
GADIDECKVI HDVCRNGECV NDRGSYHCIC KTGYTPDITG TACVDLNECN QAPKPCNFIC 2460
KNTEGSYQCS CPKGYILQED GRSCKDLDEC ATKQHNCQFL CVNTIGGFTC KCPPGFTQHH 2520
TACIDNNECT SEINLCGSKG VCQNTPGSFT CECQRGFSLD QSGASCEDVD ECEGNHRCQH 2580
GCQNIIGGYR CSCPQGYLQH YQWNQCVDEN ECLSAHVCGG ASCHNTLGSY KCMCPAGFQY 2640
EQFSGGCQDI NECGSSQAPC SYGCSNTEGG YLCGCPPGYL RIGQGHCVSG MGMGRGGPEP 2700
PASGEMDDNS LSPEACYECK INGYPKRGRK RRSTNETDAS DIQDGSEMEA NVSLASWDVE 2760
KPASFAFNIS HINNKVRILE LLPALTTLMN HNKYLIESGN EDGFFKINQK EGVSYLHFTK 2820
KKPVAGTYSL QISSTPLYKK KELNQLEDRY DKDYLSGELG DNLKMKIQIL LH 2873
Keyword

KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0245--EGF-like domain
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal

Interpro

IPR026823--cEGF
IPR001881--EGF-like_Ca-bd_dom
IPR013032--EGF-like_CS
IPR000742--EGF-like_dom
IPR000152--EGF-type_Asp/Asn_hydroxyl_site
IPR018097--EGF_Ca-bd_CS
IPR011398--FBN
IPR009030--Growth_fac_rcpt_N_dom
IPR017878--TB_dom

PROSITE

PS00010--ASX_HYDROXYL
PS00022--EGF_1
PS01186--EGF_2
PS50026--EGF_3
PS01187--EGF_CA
PS51364--TB

Pfam

PF12662--cEGF
PF07645--EGF_CA
PF00683--TB

Gene Ontology

GO:0005604--C:basement membrane
GO:0070062--C:extracellular exosome
GO:0031012--C:extracellular matrix
GO:0005576--C:extracellular region
GO:0005615--C:extracellular space
GO:0001527--C:microfibril
GO:0005509--F:calcium ion binding
GO:0005201--F:extracellular matrix structural constituent
GO:0009653--P:anatomical structure morphogenesis
GO:0043010--P:camera-type eye development
GO:1990314--P:cellular response to insulin-like growth factor stimulus
GO:0071560--P:cellular response to transforming growth factor beta stimulus
GO:0048048--P:embryonic eye morphogenesis
GO:0007507--P:heart development
GO:0001822--P:kidney development
GO:0001656--P:metanephros development
GO:0048050--P:post-embryonic eye morphogenesis
GO:0090287--P:regulation of cellular response to growth factor stimulus
GO:0001501--P:skeletal system development