dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052296
Uniprot Accession G3V9J6; G3V9J6_RAT;
Genbank Protein ID XP_008760909.1;
Genbank Nucleotide ID XM_008762687.1;
Protein Name Protein Abcb1a
Protein Synonyms/Alias
Gene Name Abcb1b
Gene Synonyms/Alias Abcb1a;rCG_41101;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
658LTSEKSKSPLIRRSIPhosphoSitePlus22135298
Sequence
(Fasta)
MEFEEGLNGT ADKNFSKMGK KSKKEKEKKP AVGIFGMFRY ADWLDKLCMA LGTLAAIIHG 60
TLLPLLMLVF GYMTDSFTQA ETRILPSVTN QSEINSTQTV SDSSLEEDMA MYAYYYTGIG 120
AGVLIVAYIQ VSLWCLAAGR QIHKIRQKFF HAIMNQEIGW FDVNDAGELN TRLTDDVSKI 180
NDGIGDKLGM FFQSITTFSA GFIIGFISGW KLTLVILAVS PLIGLSSAMW AKVLTSFTNK 240
ELQAYAKAGA VAEEVLAAIR TVIAFGGQKK ELERYNKNLE EAKRVGIKKA ITANISIGIA 300
YLLVYASYAL AFWYGTSLVL SNEYSIGQVL TVFFSILLGT FSIGHLAPNI EAFANARGAA 360
YEIFKIIDNE PSIDSFSTKG HKPDSIMGNL EFKNVYFNYP SRSEVKILKG LNLKVKSGQT 420
VALVGNSGCG KSTTVQLLQR LYDPIEGEVS IDGQDIRTIN VRYLREIIGV VSQEPVLFAT 480
TIAENIRYGR ENVTMDEIEK AVKEANAYDF IMKLPHKFNT LVGERGAQLS GGQKQRIAIA 540
RALVRNPKIL LLDEATSALD TESEAVVQAA LDKAREGRTT IVIAHRLSTV RNADVIAGFD 600
GGVIVEQGNH EELMKEKGIY FKLVMTQTRG NEIEPGNNAY ESQSDTGASE LTSEKSKSPL 660
IRRSIRRSIH RRQDQERRLS SKEDVDEDVP MVSFWQILKL NISEWPYLVV GVLCAVINGC 720
IQPVFAIVFS KIVGVFSRDD DHETKQRNCN LFSLLFLVMG MISFVTYFFQ GFTFGKAGEI 780
LTKRLRYMVF KSMLRQDISW FDDHKNTTGS LTTRLASDAS NVKGAMGSRL AVVTQNVANL 840
GTGIILSLVY GWQLTLLLVV IIPLIVLGGI IEMKLLSGQA LKDKKELEIS GKIATEAIEN 900
FRTVVSLTRE QKFETMYAQS LQIPYRNALK KAHVFGITFA FTQAMIYFSY AACFRFGAYL 960
VARELMTFEN VMLVFSAVVF GAMAAGNTSS FAPDYAKAKV SASHIIRIIE KIPEIDSYST 1020
EGLKPNWLEG NVKFNGVMFN YPTRPNIPVL QGLSFEVKKG QTLALVGSSG CGKSTVVQLL 1080
ERFYNPMAGT VFLDGKEIKQ LNVQWLRAHL GIVSQEPILF DCSITENIAY GDNSRVVSHE 1140
EIVRAAREAN IHQFIDSLPE KYNTRVGDKG TQLSGGQKQR IAIARALVRQ PHILLLDEAT 1200
SALDTESEKV VQEALDKARE GRTCIVIAHR LSTIQNADLI VVIQNGQVKE HGTHQQLLAQ 1260
KGIYFSMVQA GAKRS 1276
Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003593--AAA+_ATPase
IPR011527--ABC1_TM_dom
IPR003439--ABC_transporter-like
IPR017871--ABC_transporter_CS
IPR027417--P-loop_NTPase

PROSITE

PS50929--ABC_TM1F
PS00211--ABC_TRANSPORTER_1
PS50893--ABC_TRANSPORTER_2

Pfam

PF00664--ABC_membrane
PF00005--ABC_tran

Gene Ontology

GO:0016324--C:apical plasma membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0016020--C:membrane
GO:0005524--F:ATP binding
GO:0042626--F:ATPase activity, coupled to transmembrane movement of substances
GO:0015238--F:drug transmembrane transporter activity
GO:0005215--F:transporter activity
GO:0071356--P:cellular response to tumor necrosis factor
GO:0006855--P:drug transmembrane transport
GO:0015893--P:drug transport
GO:0014045--P:establishment of endothelial blood-brain barrier
GO:0007595--P:lactation
GO:0001890--P:placenta development
GO:0046685--P:response to arsenic-containing substance
GO:0042493--P:response to drug
GO:0001666--P:response to hypoxia
GO:0010212--P:response to ionizing radiation
GO:0014070--P:response to organic cyclic compound
GO:0048545--P:response to steroid hormone
GO:0006810--P:transport