dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052284
Uniprot Accession G3V968; G3V968_RAT;
Genbank Protein ID NP_001099810.1;
Genbank Nucleotide ID NM_001106340.1;
Protein Name U3 small nucleolar ribonucleoprotein protein MPP10
Protein Synonyms/Alias
Gene Name Mphosph10
Gene Synonyms/Alias Mphosph10_predicted;rCG_24759;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
164RKPDPRKSPAFSDEDPhosphoSitePlus;curated22135298; 23712012; 21630457; 22276854
168PRKSPAFSDEDSDLDPhosphoSitePlus;curated22135298; 23712012; 21630457; 22276854
172PAFSDEDSDLDFDISPhosphoSitePlus;curated22135298; 23712012; 21630457; 22276854
225VEKEEEKTPDGEEEEPhosphoSitePlus;curated22135298; 23712012
244DLFEDIDSDENEGGLPhosphoSitePlus;curated22135298; 23712012; 21630457
342DEAEDTSSLAVKQEScurated23712012; 21630457
Sequence
(Fasta)		MAPRVFRRQT LERCLREVRK ATNRPECFLT IQNGLASNLT SLTKVLYDFN KILEHGRISG 60
SPLQKLEIKS FDDEQIWQQL ELQNEPVLQY FQDAVSEAVE DEDLSLLPEC EDEECEEDAS 120
EVEADNQENV ETDLEDEPLS DEGGHVPKGG DRAKSSRKPD PRKSPAFSDE DSDLDFDISK 180
LEQQTKMQIK PPRKPREKSV VDDKFFKLSE MESFLEKVEK EEEKTPDGEE EEEEDIDLFE 240
DIDSDENEGG LFGKQKIKSN KSSRNLKYKD FFDPVESDEE MTGVEGELGS DEEEGLPEEA 300
ADSMSESDED NDLEEDENSG QQKGLKRVTF ALPDDEAEDT SSLAVKQESD EVKSSFEKRQ 360
EKMNEKIASL EKELLDKKPW QLQGEVTAQK RPENSLLEET LHFDHAVRMA PVITEETTLH 420
LEDIIKQRIR DRAWDDVERK EKPKEDAYEY KKRLTLDHEK SKLSLAEIYE QEYIKLNQQK 480
AEEEDNPEHV EIQKMMDSLF LKLDALSNFH FIPKPPVPEI KVVSNLPAIT MEEVAPVSVS 540
DAALLAPEEI KEKNKAGDLK TAAEKTATDK KRERRKKKYQ KRLKIKEKEK RRKLLEKSNP 600
DHSKSSRAAA SEKLKQLTKT GKVSLLKDER KDKPLKSSQA FFSKLQDQVK MQINDAKQPG 660
KIKKKKQDIS VHKLKL 677
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0687--Ribonucleoprotein
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0543--Viral nucleoprotein
KW-0946--Virion
Interpro

IPR012173--snoRNP_Mpp10
PROSITE
Pfam

PF04006--Mpp10
Gene Ontology

GO:0034457--C:Mpp10 complex
GO:0005732--C:small nucleolar ribonucleoprotein complex
GO:0032040--C:small-subunit processome
GO:0019013--C:viral nucleocapsid
GO:0044822--F:poly(A) RNA binding
GO:0010923--P:negative regulation of phosphatase activity
GO:0006364--P:rRNA processing