dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052279
Uniprot Accession G3V926; G3V926_RAT;
Genbank Protein ID NP_001101058.1;
Genbank Nucleotide ID NM_001107588.1;
Protein Name Conserved helix-loop-helix ubiquitous kinase (Predicted)
Protein Synonyms/Alias
Gene Name Chuk
Gene Synonyms/Alias Chuk_predicted;rCG_57595;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
176AKDVDQGSLCTSFVGPhosphoSitePlus22135298
180DQGSLCTSFVGTLQYPhosphoSitePlus;curated22135298; 22817900
Sequence
(Fasta)
MERPPGLRPG AGGPWEMRER LGTGGFGNVS LYQHRELDLK IAIKSCRLEL STKNRERWCH 60
EIQIMKKLNH ANVVKACDVP EELNFLINDV PLLAMEYCSG GDLRKLLNKP ENCCGLKESQ 120
ILSLLSDIGS GIRYLHENKI IHRDLKPENI VLQDVGGKIM HKIIDLGYAK DVDQGSLCTS 180
FVGTLQYLAP ELFENKPYTA TVDYWSFGTM VFECIAGYRP FLHHLQPFTW HEKIKKKDPK 240
CIFACEEMTG EVRFSSHLPQ PNNLCSLIVE PMESWLQLML NWDPQQRGGP IDPPLKQPKC 300
FVLMDNILNL KIVHILNMTS AKIISFLLPY DESLHSLQSR IERETGINTG SQELLSETGI 360
SLDPRKPASQ CVLDGVRGCD SYMVYLFDKS KTVYEGPFAS RSLSDCVNYI VQDSKIQLPV 420
TQLRKVWAEA VHYVSGLKED YSRLFQGQRA AMLSLLRYNA NLTKMKNTLI SASQQLKAKL 480
EFFRKSIQLD LERYSEQMTY GISSEKMLKA WKEMEEKAIH YSEVGVIGYL EDQIMSLHTE 540
IMELQKSPYG RRQGDLMESL EQRAIDLYKQ LKHRPTDHSY SDSTEMVKII VHTVQSQDRV 600
LKELFGHLSK LLGCKQKIID LLPKVEVALS NIKEADNTVM FMQGKRQKEI WHLLKIACTQ 660
SSARSLVGSS LEGTVTPPVS AWLPPTLADR EHPLTCVVTP QDGETLAQMI EENLNCLGHL 720
STIIREANED QSSSMMSLDW SWLAE 746
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR022007--IKKbetaNEMObind
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF12179--IKKbetaNEMObind
PF00069--Pkinase

Gene Ontology

GO:0005829--C:cytosol
GO:0008385--C:IkappaB kinase complex
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005654--C:nucleoplasm
GO:0005524--F:ATP binding
GO:0008384--F:IkappaB kinase activity
GO:0046982--F:protein heterodimerization activity
GO:0071356--P:cellular response to tumor necrosis factor
GO:0007252--P:I-kappaB phosphorylation
GO:0007595--P:lactation
GO:0060749--P:mammary gland alveolus development
GO:0033598--P:mammary gland epithelial cell proliferation
GO:0002011--P:morphogenesis of an epithelial sheet
GO:0042475--P:odontogenesis of dentin-containing tooth
GO:0030316--P:osteoclast differentiation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0010034--P:response to acetate
GO:0043200--P:response to amino acid
GO:0042493--P:response to drug
GO:0033194--P:response to hydroperoxide
GO:0032496--P:response to lipopolysaccharide
GO:0035994--P:response to muscle stretch
GO:0010033--P:response to organic substance
GO:0009636--P:response to toxic substance
GO:0007266--P:Rho protein signal transduction
GO:0003009--P:skeletal muscle contraction
GO:0051146--P:striated muscle cell differentiation