dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052276
Uniprot Accession G3V918; G3V918_RAT;
Genbank Protein ID NP_001011899.2;
Genbank Nucleotide ID NM_001011899.2;
Protein Name Phosphoribosylglycinamide formyltransferase, isoform CRA_a
Protein Synonyms/Alias
Gene Name Gart
Gene Synonyms/Alias rCG_58778;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
10ARVLVIGSGGREHTLPhosphoSitePlus22135298
467ATSRPGCSVDLGGFAcurated23984901
Sequence
(Fasta)
MAARVLVIGS GGREHTLAWK LAQSPHVKQV LVAPGNAGTA SAGKISNAAV SINDHTALAR 60
FCKDEKIELV VVGPEAPLAA GIVGDLTSAG VRCFGPTAQA ALLESSKKFA KEFMDRHGVP 120
TAQWRAFTSP EDACSFIMSA DFPALVVKAS GLAAGKGVIV AKSKAEACEA VQEIMQEKSF 180
GAAGETVVVE ELLEGEEVSC LCFTDGKTVA PMPPAQDHKR LLDGDRGPNT GGMGAYCPAP 240
QVPKDLLVKI KNTILQRTVD GMQQEGVPYT GILYAGIMLT KDGPKVLEFN CRFGDPECQV 300
ILPLLKSDLY EVIQSTFDGL LSESPPVWLE NHSAVTVVMA SGGYPGAYTK GVEITGFPEA 360
QALGLQVFHA GTALKDAKVV TSGGRVLTVT AVRENLMSAL DEARKGLAAL KFEGAVYRKD 420
IGFRAVAFLQ RPRGLTYKDS GVDIAAGNML VKKIQPLAKA TSRPGCSVDL GGFAGLFDLK 480
AAGFKDPLLA SGTDGVGTKL KIAQLCNKHD SIGQDLVAMC VNDILAQGAE PLFFLDYFSC 540
GKLDLSTTEA VVAGIAAACR QAGCALLGGE TAEMPDMYPP GEYDLAGFAV GAMERHQKLP 600
QLERIAEGDA VIGVASSGLH SNGFSLVRKI VERSSLQYSS PAPGGCGDQT LGDLLLTPTR 660
IYSHSLLPII RSGRVKAFAH ITGGGLLENI PRVLPRKLGV DLDAYTWRVP KVFSWLQQEG 720
QLSEEEMART FNCGVGAALV VSKDQTEQIL HDIRQHQEDA WVIGSVVECP EDSPRVRVKN 780
LIETMQTKGS VVTNGFLRSN FPSQQKKARV AVLISGTGSN LQALIDSTRD PKSSSHIVLV 840
ISNKAAVAGL DRAERAGIPT RVINHKLYKS RVEFDNAVDH VLEEFSVDIV CLAGFMRILS 900
GPFVRKWDGK MLNIHPSLLP SFKGSNAHEQ VLEAGVTITG CTVHFVAEDV DAGQIILQEA 960
VPVQRDDTVA TLSERVKAAE HKIFPAALQL VASGAVQLGE DGKIHWAREQ 1011
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR010918--AIR_synth_C_dom
IPR011761--ATP-grasp
IPR013815--ATP_grasp_subdomain_1
IPR013816--ATP_grasp_subdomain_2
IPR002376--Formyl_transf_N
IPR001555--GART_AS
IPR016185--PreATP-grasp_dom
IPR020561--PRibGlycinamid_synth_ATP-grasp
IPR000115--PRibGlycinamide_synth
IPR020560--PRibGlycinamide_synth_C-dom
IPR020559--PRibGlycinamide_synth_CS
IPR020562--PRibGlycinamide_synth_N
IPR016188--PurM-like_N
IPR004733--PurM_cligase
IPR004607--PurN_trans
IPR011054--Rudment_hybrid_motif

PROSITE

PS50975--ATP_GRASP
PS00184--GARS
PS00373--GART

Pfam

PF00586--AIRS
PF02769--AIRS_C
PF00551--Formyl_trans_N
PF01071--GARS_A
PF02843--GARS_C
PF02844--GARS_N

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0008168--F:methyltransferase activity
GO:0004637--F:phosphoribosylamine-glycine ligase activity
GO:0004641--F:phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004644--F:phosphoribosylglycinamide formyltransferase activity
GO:0006189--P:'de novo' IMP biosynthetic process
GO:0003360--P:brainstem development
GO:0021549--P:cerebellum development
GO:0021987--P:cerebral cortex development
GO:0009235--P:cobalamin metabolic process
GO:0006544--P:glycine metabolic process
GO:0009113--P:purine nucleobase biosynthetic process
GO:0010035--P:response to inorganic substance
GO:0010033--P:response to organic substance
GO:0009156--P:ribonucleoside monophosphate biosynthetic process
GO:0046654--P:tetrahydrofolate biosynthetic process