dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052262
Uniprot Accession G3V8S6; G3V8S6_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Histidine rich calcium binding protein, isoform CRA_b
Protein Synonyms/Alias
Gene Name Hrc
Gene Synonyms/Alias rCG_53876;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 34 (View all)
PositionPeptidesSourceReferences ( PMIDs )
83REEDEDFSREYGHQVPhosphoSitePlus22135298
95HQVQDHRYPGHEVGEcurated24945867
106EVGEENVSEEVFRGHPhosphoSitePlus;curated22135298; 24945867
125HGHHKPNSEDLGDSAPhosphoSitePlus22135298
131NSEDLGDSAESHFPRPhosphoSitePlus22135298
134DLGDSAESHFPRQQSPhosphoSitePlus22135298
141SHFPRQQSHNREEEDPhosphoSitePlus22135298
152EEEDGVVSGEDHRHIPhosphoSitePlus22135298
186RVGVMENSDDKHQAHPhosphoSitePlus22135298
199AHGHHSHSKERDGLHPhosphoSitePlus22135298
210DGLHHAHSHRHQGHHPhosphoSitePlus22135298
228DDDEDGVSTEGEHQAPhosphoSitePlus22135298
238GEHQAHRYQDHDEEDcurated24945867
249DEEDDDDSDEESHAHPhosphoSitePlus;curated22135298; 24945867
253DDDSDEESHAHRLQGPhosphoSitePlus22135298
342KGKDEDESDEDDHVTPhosphoSitePlus22135298
377DDDNDGGSTENVHQAPhosphoSitePlus22135298
425EEEDEAVSTEHWHQSPhosphoSitePlus22135298
465SHRPQGHSAEEDSLEPhosphoSitePlus22135298
470GHSAEEDSLEDSTNEPhosphoSitePlus22135298
Sequence
(Fasta)		MGFQEPWLYS CLLWATVAIL LVPPVVTQEL RGTGLGLGNW NNNAGIPGSS EDLSTEYGHH 60
IHSHGAYQGE KDRHHREEDE DFSREYGHQV QDHRYPGHEV GEENVSEEVF RGHVRQLHGH 120
HKPNSEDLGD SAESHFPRQQ SHNREEEDGV VSGEDHRHIP RHDHHGNEEE DDDGEEEERV 180
GVMENSDDKH QAHGHHSHSK ERDGLHHAHS HRHQGHHDED DDDEDGVSTE GEHQAHRYQD 240
HDEEDDDDSD EESHAHRLQG QEDENDDEDG DSSENGHQTQ DHQGHKEQDD DDDEEEEEEE 300
EEEEEEEEEE EEEEEDDDDD STEHRHRHQT QGHRKGKDED ESDEDDHVTR HGRRGHEDED 360
DDDDDDDDDD DDNDGGSTEN VHQAHRHRGH EHEDDGDDSE EDYHHVPSHG HQSHQNEEEE 420
DEAVSTEHWH QSPRHAHHDL GRENQEEATV KYSRHVASHR PQGHSAEEDS LEDSTNEVPG 480
HHHHRVSRDG DEDISTEFGH KAPRHRLQDQ DEWTRQGHGK SVQEDIGHQP LQPTGPGSGE 540
SRKEDDHSSQ EGDEDLKQRQ EAHSEEEEEE EEGHGLPMSL EDEEEEEKDK KESKGDRAAV 600
SAPLSHHRKH DDDDDGDGDD DDDDNDDDDE ILEENLLPFT IIPNPLAGRE VAREGSSEEE 660
SREVTGQQDA QEYENYQPGS LCGYCSFCNR CSECESCHCD EENMGEHCDQ CQHCQFCYLC 720
PLVCDTLCTP GSYVDYFSSS VYQAVADMLE TQEP 755
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0732--Signal
Interpro

IPR015666--His-rich_Ca-bd
IPR019552--Hist_rich_Ca-bd
PROSITE
Pfam

PF10529--Hist_rich_Ca-bd
Gene Ontology

GO:0005829--C:cytosol
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0030018--C:Z disc
GO:0005509--F:calcium ion binding
GO:0051480--P:cytosolic calcium ion homeostasis
GO:0010460--P:positive regulation of heart rate
GO:1901899--P:positive regulation of relaxation of cardiac muscle
GO:1901844--P:regulation of cell communication by electrical coupling involved in cardiac conduction
GO:0033135--P:regulation of peptidyl-serine phosphorylation
GO:0010880--P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0060314--P:regulation of ryanodine-sensitive calcium-release channel activity