dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052261
Uniprot Accession G3V8S2; G3V8S2_RAT;
Genbank Protein ID NP_001157532.1;
Genbank Nucleotide ID NM_001164060.1;
Protein Name SHC-transforming protein 1
Protein Synonyms/Alias
Gene Name Shc1
Gene Synonyms/Alias rCG_62677;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
36TPPEELPSPSASSLGPhosphoSitePlus22135298
349EEPPDHQYYNDFPGKPhosphoSitePlus22135298
350EPPDHQYYNDFPGKEPhosphoSitePlus22135298
Sequence
(Fasta)		MDLLPPKPKY NPLRNESLSS LEEGASGSTP PEELPSPSAS SLGPILPPLP GDDSPTTLCS 60
FFPRMSNLKL ANPAGGRLGP KGEPGKAAED GEGSAGAALR DSGLLPLLQD MNKLSGGGGR 120
RTRVEGGQLG GEEWTRHGSF VNKPTRGWLH PNDKVMGPGV SYLVRYMGCV EVLQSMRALD 180
FNTRTQVTRE AISLVCEAVP GAKGAMRRRK PCSRPLSSIL GRSNLKFAGM PITLTVSTSS 240
LNLMAADCKQ IIANHHMQSI SFASGGDPDT AEYVAYVAKD PVNQRACHIL ECPEGLAQDV 300
ISTIGQAFEL RFKQYLRNPP KLVTPHDRMA GFDGSAWDEE EEEPPDHQYY NDFPGKEPPL 360
GGVVDMRLRE GAARPTLPST QMPSHLGATL PIGQHVTGDH EVRKQMLPPP PCPGRELFDD 420
PSYVNIQNLD KARQAGGGAG PPNPSVNGSA PRDLFDMKPF EDALRVPPAP QSMSMAEQLQ 480
GESWFHGKLS RREAEALLQL NGDFLVREST TTPGQYVLTG LQSGQPKHLL LVDPEGVVRT 540
KDHRFESVSH LISYHMDNHL PIISAGSELC LQQPVDRKV
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0727--SH2 domain
Interpro

IPR011993--PH/PTB_dom
IPR006019--PID_Shc-like
IPR006020--PTB/PI_dom
IPR000980--SH2
IPR029586--Shc1/ShcA
PROSITE

PS01179--PID
PS50001--SH2
Pfam

PF00640--PID
PF00017--SH2
Gene Ontology

GO:0005737--C:cytoplasm
GO:0010008--C:endosome membrane
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0051219--F:phosphoprotein binding
GO:0001784--F:phosphotyrosine binding
GO:0032403--F:protein complex binding
GO:0019901--F:protein kinase binding
GO:0051721--F:protein phosphatase 2A binding
GO:0030036--P:actin cytoskeleton organization
GO:0031532--P:actin cytoskeleton reorganization
GO:0000187--P:activation of MAPK activity
GO:0007568--P:aging
GO:0001525--P:angiogenesis
GO:0032869--P:cellular response to insulin stimulus
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007507--P:heart development
GO:0000165--P:MAPK cascade
GO:0030182--P:neuron differentiation
GO:0031175--P:neuron projection development
GO:0031100--P:organ regeneration
GO:0048661--P:positive regulation of smooth muscle cell proliferation
GO:0045907--P:positive regulation of vasoconstriction
GO:0051384--P:response to glucocorticoid
GO:0042542--P:response to hydrogen peroxide
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0035094--P:response to nicotine
GO:0014070--P:response to organic cyclic compound
GO:0009636--P:response to toxic substance
GO:0016337--P:single organismal cell-cell adhesion