| Tag |
Content |
| dbPAF ID |
dbPAF-0052247 |
| Uniprot Accession |
G3V8L3; G3V8L3_RAT;
|
| Genbank Protein ID |
NP_001002016.2;
|
| Genbank Nucleotide ID |
NM_001002016.2;
|
| Protein Name |
Lamin A, isoform CRA_b |
| Protein Synonyms/Alias |
|
| Gene Name |
Lmna |
| Gene Synonyms/Alias |
rCG_62695; |
| Organism |
Rattus norvegicus(Rat) |
| NCBI Taxa ID |
10116 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | METPSQRRAT RSGAQASSTP LSPTRITRLQ EKEDLQELND RLAVYIDRVR SLETENAGLR 60
LRITESEEVV SREVSGIKAA YEAELGDARK TLDSVAKERA RLQLELSKVR EEFKELKARN 120
TKKEGDLLAA QARLKDLEAL LNSKEAALST ALSEKRTLEG ELHDLRGQVA KLEAALGEAK 180
KQLQDEMLRR VDAENRLQTL KEELDFQKNI YSEELRETKR RHETRLVEID NGKQREFESR 240
LADALQELRA QHEDQVEQYK KELEKTYSAK LDNARQSAER NSNLVGAAHE ELQQSRIRID 300
SLSAQLSQLQ KQLAAKEAKL RDLEDSLARE RDTSRRLLAE KEREMAEMRA RMQQQLDEYQ 360
ELLDIKLALD MEIHAYRKLL EGEEERLRLS PSPTSQRSRG RASSHSSQSQ GGGSVTKKRK 420
LESSESRSSF SQHARTSGRV AVEEVDEEGK FVRLRNKSNE DQSMGNWQIR RQNGDDPLMT 480
YRFPPKFTLK AGQVVTIWAS GAGATHSPPT DLVWKAQNTW GCGSSLRTAL INATGEEVAM 540
RKLVRSLTMV EDNDDEEEDG DELLHHHRGS HCSSSGDPAE YNLRSRTVLC GTCGQPADKA 600
ASGSGAQVGG SISSGSSASS VTVTRSFRSV GGSGGGSFGD NLVTRSYLLG NSSPRTQSSQ 660
NCSIM
666Fasta Sequence
>G3V8L3|Lmna|Rattus norvegicus(Rat)
METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQSQGGGSVTKKRKLESSESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIRRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGSSLRTALINATGEEVAMRKLVRSLTMVEDNDDEEEDGDELLHHHRGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKAASGSGAQVGGSISSGSSASSVTVTRSFRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSSQNCSIM
|
| Keyword |
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0403--Intermediate filament
KW-1267--Proteomics identification
KW-1185--Reference proteome
|
| Interpro |
IPR001664--IF
IPR018039--Intermediate_filament_CS
IPR001322--Lamin_tail_dom
|
| PROSITE |
PS00226--IF
|
| Pfam |
PF00038--Filament
PF00932--LTD
|
| Gene Ontology |
GO:0005638--C:lamin filament
GO:0016363--C:nuclear matrix
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0008157--F:protein phosphatase 1 binding
GO:0005198--F:structural molecule activity
GO:0071456--P:cellular response to hypoxia
GO:0030951--P:establishment or maintenance of microtubule cytoskeleton polarity
GO:0007517--P:muscle organ development
GO:1904178--P:negative regulation of adipose tissue development
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0090201--P:negative regulation of release of cytochrome c from mitochondria
GO:0006998--P:nuclear envelope organization
GO:0090343--P:positive regulation of cell aging
GO:0045669--P:positive regulation of osteoblast differentiation
GO:0030334--P:regulation of cell migration
GO:1900180--P:regulation of protein localization to nucleus
GO:0009612--P:response to mechanical stimulus
GO:0007283--P:spermatogenesis
GO:0035105--P:sterol regulatory element binding protein import into nucleus
GO:0055015--P:ventricular cardiac muscle cell development
|
