dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052238
Uniprot Accession G3V8C9; G3V8C9_RAT;
Genbank Protein ID NP_001263643.1; XP_006235358.1; XP_006235359.1; XP_008760517.1;
Genbank Nucleotide ID NM_001276714.1; XM_006235296.2; XM_006235297.1; XM_008762295.1;
Protein Name Nuclear receptor coactivator 6
Protein Synonyms/Alias
Gene Name Ncoa6
Gene Synonyms/Alias rCG_37248;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
2013KTPSRRNSRTEEPTMPhosphoSitePlus;curated22135298; 21630457
2015PSRRNSRTEEPTMAScurated21630457
Sequence
(Fasta)
MVLDDLPNFE DIYTSLCSST MGDSEVEFDS GLEDDDTKSD SILEDSTIFV AFKGNIDDKD 60
FKWKLDTILQ SVPGLLHMES SKLKVQKVEP WNSVRVTFNI PREAAERLRI LAQSNNQQLR 120
DLGILSVQIE GEGAINLALG QNRSQDVRMN GPVVSGNSVR MEAGFPMASG PGLIRMTSPA 180
TVMMPQGGNA SSSMMAPGPN PELQPRTPRP ASQSDAMDPL LSGLHIQQQS HPSGSLPPAH 240
HPMQPVPVNR QMNPANFPQL QQQQQQQQQQ QQQQQQQQQQ QLQTRPLQQH QQQQPQGIRP 300
QFTAPTQVPV PPGWNQLPSG ALQPPPAQGS LGPMTTNQGW KKAPLPSPMQ AQLQARPSLA 360
TVQTPSHPPP PYPFGSQQAS QAHTNFPQMS NPGQFTAPQM KSLQGGPSRV PTPLQQPHLT 420
NKSPASSPSS FQQGSPASSP TVNQTQQQMG PRPPQNNPLS QGFQQPVSSP GRNPMVQQGN 480
VPPNFMVMQQ QPPSQGPPSL HPGLGGMPKR LPPGFSAGQA NPNFMQGQVP STTAATPGNS 540
GALQLQANQS VQHAGGQGAG PPQNQMQVSH GPPNMMQPSL MGIHGNINNQ QAGSSGVPQV 600
TLGSMQGQPQ QGPPSQLMGM HQQIVPSQGQ MAQQQGTLNP QNPMILSRAQ LMPQGQMMVN 660
AQNQNLGPSP QRMTPPKQML PQQGPQMMAP HNQMMGPQGQ VLLQQNPMIE QIMTNQMQGN 720
KAQFNSQNQS NVMPGPAQIM RGPTPNMQGN MVQFTGQMSG QMLPQQGPVS NSPSQVMGIQ 780
GQVLRPPGPS PHMAQQHTDP ATTANNDVNL SQMMPDVSMQ QTSMVPPHVQ SMQGNSASGS 840
HFSGHGVSFN APFGGAPNGT QMSCGQNPGF PVNKDVTLTS PLLVNLLQSD ISAGHFGVNN 900
KQNNTNANKQ KKKKPPRKKK NCHQDLNTPD SRPAGLEEVD QQSLPGEQGI NLDNTGPKLP 960
DFSNRPPGYP TQPVEQRPLQ QMPPQLMQHV APPPQPPQQQ PQPQLPQQQP QPQPPPPSQP 1020
QSQQQQQQMM MMLMMQQDPK SIRLPVSQNV HPPRGPLNPD SQRVPMQQSG NVPVMVSLQG 1080
PASVPPSPDK QRMPMPVNTP LGSNSRKMVY QESPQNSSSP LGEMPSLPEA GGSEVPSVSG 1140
GPSNMPSHLV VSQNQLMMTG PKPGPSPLSA TQGATPQQPP VNSLPSSHGH HFPNVAAPTQ 1200
TSRPKTPNRA SPRPYYPQTP NNRPPSTEPS EISLSPERLN ASIAGLFPPQ INIPLPPRPN 1260
LNRGFDQQGL NPTTLKAIGQ APSNLTVSNP PNFAAPQAHK LDSVVVSSGK QSNPGTTKRA 1320
SPSNSRRSSP GSSRKTTPSP GRQNSKAPKL TLASQTSTTL LQNMELPRNV LVGPTPLANP 1380
PLSGSFPNNN GLNSQNPTVP APAVGTVVED NKESLNVPQD SDCQNSQGRK EQVNTELKAV 1440
PIQEAKMVVP EDQSKKDGQP LDPNKLPSVE ENKTLMSPAM REAPTSLSQL LDNSGAPNVT 1500
IKPPGLTDLE VTPPAVSGED LKKASVIPTL QDPSSKEPSN SLNLPHSNEP CSTLAHPELS 1560
EVSSNIAPSI PPVMSRPVSS SSISTPLPPN QITVFVTSNP ITTSSNTSAA LPTHLQSALM 1620
STVVTMPNVG NKVMVSEGQS AAQSNARPQF ITPVFINSSS IIQVMKGSQP STIPATPLTT 1680
NSGLMPPSVA VVGPLHIPQN IKFSSAPVTP NVPSSSPAPN IQTGRPLVLS SRATPVPLPS 1740
PPCTSSPVVA PNPSVQQVKE LNPDEASPQT NTSADQSTLP SSQPTTVVSP LLANSPGSSA 1800
NRRSPVSSSK GKGKVDKIGQ ILLTKACKKV TGSLEKGEEQ YGADGETEGP GLETTTPGLM 1860
GTEQCSTELD SKTPTPSAPT LLKMTSSPMG PSSTSTGPIL PGGALPTSVR SVVTTLVPSE 1920
LISTAPTTKG NHGGITSEPL AGGLVEEKVG SHPELLPSIA PSQTLVPKES PATALQGSVG 1980
RPELEANAAI ASGQSSEPKE TVEKSKTPSR RNSRTEEPTM ASENVENGHR KRSSRPASAS 2040
SSTKDITGAV QSKRRKSK 2059
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-0675--Receptor
KW-1185--Reference proteome

Interpro

IPR026638--NCOA6

PROSITE
Pfam
Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0035259--F:glucocorticoid receptor binding
GO:0016922--F:ligand-dependent nuclear receptor binding
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0035257--F:nuclear hormone receptor binding
GO:0042975--F:peroxisome proliferator activated receptor binding
GO:0019904--F:protein domain specific binding
GO:0042803--F:protein homodimerization activity
GO:0042974--F:retinoic acid receptor binding
GO:0046965--F:retinoid X receptor binding
GO:0046966--F:thyroid hormone receptor binding
GO:0007420--P:brain development
GO:0006974--P:cellular response to DNA damage stimulus
GO:0006352--P:DNA-templated transcription, initiation
GO:0007507--P:heart development
GO:0080182--P:histone H3-K4 trimethylation
GO:0060716--P:labyrinthine layer blood vessel development
GO:0030099--P:myeloid cell differentiation
GO:0001541--P:ovarian follicle development
GO:0035774--P:positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0002793--P:positive regulation of peptide secretion
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter