| Tag |
Content |
| dbPAF ID |
dbPAF-0052218 |
| Uniprot Accession |
G3V7Y8; G3V7Y8_RAT;
|
| Genbank Protein ID |
NP_001094249.1;
|
| Genbank Nucleotide ID |
NM_001100779.1;
|
| Protein Name |
Activation-induced cytidine deaminase |
| Protein Synonyms/Alias |
|
| Gene Name |
aicda |
| Gene Synonyms/Alias |
rCG_29802; |
| Organism |
Rattus norvegicus(Rat) |
| NCBI Taxa ID |
10116 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 146 | MTFKDYFYCWNTFVE | PhosphoSitePlus | 22135298 |
|
Sequence
(Fasta) | MDSLLMKQKK FLYHFKNVRW AKGRHETYLC YVVKRRDSAT SFSLDFGHLR NKSGCHVELL 60
FLRYISDWDL DPGRCYRVTW FTSWSPCYDC ARHVAEFLRW NPNLSLRIFT ARLYFCEDRK 120
AEPEGLRRLH RAGVQIGIMT FKDYFYCWNT FVENHERTFK AWEGLHENSV RLTRQLRRIL 180
LPLYEVDDLR DAFRILGL
199Fasta Sequence
>G3V7Y8|aicda|Rattus norvegicus(Rat)
MDSLLMKQKKFLYHFKNVRWAKGRHETYLCYVVKRRDSATSFSLDFGHLRNKSGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVAEFLRWNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIGIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLTRQLRRILLPLYEVDDLRDAFRILGL
|
| Keyword |
KW-0181--Complete proteome
KW-1185--Reference proteome
|
| Interpro |
IPR016192--APOBEC/CMP_deaminase_Zn-bd
IPR013158--APOBEC_N
IPR002125--CMP_dCMP_Zn-bd
IPR016193--Cytidine_deaminase-like
|
| PROSITE |
PS00903--CYT_DCMP_DEAMINASES_1
PS51747--CYT_DCMP_DEAMINASES_2
|
| Pfam |
PF08210--APOBEC_N
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0000178--C:exosome (RNase complex)
GO:0005634--C:nucleus
GO:0016814--F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
GO:0008270--F:zinc ion binding
GO:0071222--P:cellular response to lipopolysaccharide
GO:0009972--P:cytidine deamination
GO:0080111--P:DNA demethylation
GO:0045190--P:isotype switching
GO:0090310--P:negative regulation of methylation-dependent chromatin silencing
GO:0016446--P:somatic hypermutation of immunoglobulin genes
|
