dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052200
Uniprot Accession G3V7M0; G3V7M0_RAT;
Genbank Protein ID NP_001128312.1;
Genbank Nucleotide ID NM_001134840.1;
Protein Name Protein Cnot1
Protein Synonyms/Alias
Gene Name Cnot1
Gene Synonyms/Alias rCG_39079;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
318QSISAPGSGIWSDGKcurated23984901
1061VTKPTGVSFKKDVPPcurated23984901
Sequence
(Fasta)		MNLDSLSLAL SQISYLVDNL TKKNYRASQQ EIQHIVNRHG PEADRHLLRC LFSHVDFSGD 60
GKSSGKDFHQ TQFLIQECAS LITKPNFIST LSYAIDNPLH YQKSLKPAPH LFAQLSKVLK 120
LSKVQEVIFG LALLNSSSPD LRGFAAQFIK QKLPDLLRSY IDADVSGNQE GGFQDIAIEV 180
LHLLLSHLLF GQKGAFGVGQ EQIDAFLKTL RRDFPQERCP VVLAPLLYPE KRDILMDRIL 240
PDSGGVAKTM MESSLADFMQ EVGYGFCASI EECRNIIMQF GVREVTAAQV ARVLGMMART 300
HSGLTDGIPL QSISAPGSGI WSDGKDKSEG AQAHTWNVEV LIDVLKELNP SLNFKEVTYE 360
LDHPGFQIRD SKGLHNVVYG IQRGLGMEVF PVDFIYRPWK HAEGQLSFIQ HSLINPEVFC 420
FADYPCHTVA TDILKAPPED DNREIATWKS LDLIESLLRL AEVGQYEQVK QLFSFPIKHC 480
PDMLVLALLQ INTSWHTLRH ELISTLMPIF LGNHPNSAII LHYAWHGQGQ SPSIRQLIMH 540
AMAEWYMRGE QYDQAKLSRI LDVAQDLKAL SMLLNGTPFA FVIDLAALAS RREYLKLDKW 600
LTDKIREHGE PFIQACMTFL KRRCPSILGG LAPEKDQPKS AQLPAETLAT MLACLQACAG 660
SVSQELSETI LTMVANCSNV MNKARQPPPG VMPKGRPPSA SSLDAISPVQ IDPLAGMASL 720
SIGGSAAPHT QSMQGFPPNL GSAFSTPQSP AKAFPPLSTP NQTTAFSGIG GLSSQLPVGG 780
LGTGSLTGIG TGALGLPAVN SDPFVQRKLG TSGLNQPTFQ QSKMKPSDLS QVWPEANQHF 840
SKEIDDEANS YFQRIYNHPP HPTMSVDEVL EMLQRFKDST IKREREVFNC MLRNLFEEYR 900
FFPQYPDKEL HITACLFGGI IEKGLVTYMA LGLALRYVLE ALRKPFGSKM YYFGIAALDR 960
FKNRLKDYPQ YCQHLASISH FMQFPHHLQE YIEYGQQSRD PPVKMQGSIT TPGSIALAQA 1020
QAQAQVPAKA PLAGQVNTMV TTSTTTTVAK TVTVTKPTGV SFKKDVPPSI NTTNIDTLLV 1080
ATDQTERIVE PPENIQEKIA FIFNNLSQSN MTQKVEELKE TVKEEFMPWV SQYLVMKRVS 1140
IEPNFHSLYS NFLDTLKNPE FNKMVLNETY RNIKVLLTSD KAAANFSDRS LLKNLGHWLG 1200
MITLAKNKPI LHTDLDVKSL LLEAYVKGQQ ELLYVVPFVA KVLESSIRSL VFRPPNPWTM 1260
AIMNVLAELH QEHDLKLNLK FEIEVLCKNL ALDINELKPG NLLKDKDRLK NLDEQLSAPK 1320
KDVKQPEELP AITTTTTSTT PATSTTCTAT VPPQPQYSYH DINVYSLAGL APHITLNPTI 1380
PLFQAHPQLK QCVRQAIERA VQELVHPVVD RSIKIAMTTC EQIVRKDFAL DSEESRMRIA 1440
AHHMMRNLTA GMAMITCREP LLMSISTNLK NSFASALRTA SPQQREMMDQ AAAQLAQDNC 1500
ELACCFIQKT AVEKAGPEMD KRLATEFELR KHARQEGRRY CDPVVLTYQA ERMPEQIRLK 1560
VGGVDPKQLA VYEEFARNVP GFLPTNDLSQ PTGFLAQPMK QAWATDDVAQ IYDKCITELE 1620
QHLHAIPPTL AMNPQAQALR SLLEVVVLSR NSRDAIAALG LLQKAVEGLL DATSGADADL 1680
LLRYRECHLL VLKGLQDGRA YGSPWCNKQI TRCLIECRDE YKYNVEAVEL LIRNHLVNMQ 1740
QYDLHLAQSM ENGLNYMAVA FAMQLVKILL VDERSVAHIT EADLFHTIET LMRINAHSRG 1800
NAPEGLPQLM EVVRSNYEAM IDRAHGGPNF MMHSGISQAS EYDDPPGLRE KAEYLLREWV 1860
NLYHSAAAGR DSTKAFSAFV GQMHQQGILK TDDLITRFFR LCTEMCVEIS YRAQAEQQHN 1920
PAANPTMIRA KCYHNLDAFV RLIALLVKHS GEATNTVTKI NLLNKVLGIV VGVLLQDHDV 1980
RQSEFQQLPY HRIFIMLLLE LNAPEHVLET INFQTLTAFC NTFHILRPTK APGFVYAWLE 2040
LISHRIFIAR MLAHTPQQKG WPMYAQLLID LFKYLAPFLR NVELTKPMQI LYKGTLRVLL 2100
VLLHDFPEFL CDYHYGFCDV IPPNCIQLRN LILSAFPRNM RLPDPFTPNL KVDMLSEINI 2160
APRILTNFTG VMPPQFKKDL DSYLKTRSPV TFLSDLRSNL QVSNEPGNRY NLQLINALVL 2220
YVGTQAIAHI HNKGSTPSMS TITHSAHMDI FQNLAVDLDT EGRYLFLNAI ANQLRYPNSH 2280
THYFSCTMLY LFAEANTEAI QEQITRVLLE RLIVNRPHPW GLLITFIELI KNPAFKFWNH 2340
EFVHCAPEIE KLFQSVAQCC MGQKQAQQVM EGTGAS 2377
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR007196--CCR4-Not_Not1_C
IPR024557--CCR4-Not_Not1su_DUF3819
IPR032191--CNOT1_CAF1_bind
IPR032194--CNOT1_HEAT
IPR032193--CNOT1_TTP_bind
PROSITE
Pfam

PF16415--CNOT1_CAF1_bind
PF16418--CNOT1_HEAT
PF16417--CNOT1_TTP_bind
PF12842--DUF3819
PF04054--Not1
Gene Ontology

GO:0030015--C:CCR4-NOT core complex
GO:0000932--C:cytoplasmic mRNA processing body
GO:0005615--C:extracellular space
GO:0005654--C:nucleoplasm
GO:0005778--C:peroxisomal membrane
GO:0044822--F:poly(A) RNA binding
GO:0004535--F:poly(A)-specific ribonuclease activity
GO:0032947--F:protein complex scaffold
GO:0035195--P:gene silencing by miRNA
GO:0033147--P:negative regulation of intracellular estrogen receptor signaling pathway
GO:0048387--P:negative regulation of retinoic acid receptor signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0017148--P:negative regulation of translation
GO:0000288--P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0010606--P:positive regulation of cytoplasmic mRNA processing body assembly
GO:0060213--P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:2000036--P:regulation of stem cell population maintenance