Tag |
Content |
dbPAF ID |
dbPAF-0052186 |
Uniprot Accession |
G3V783; G3V783_RAT; |
Genbank Protein ID |
NP_001178794.1; |
Genbank Nucleotide ID |
NM_001191865.1; |
Protein Name |
Protein Ripk2 |
Protein Synonyms/Alias |
|
Gene Name |
Ripk2 |
Gene Synonyms/Alias |
rCG_54865; |
Organism |
Rattus norvegicus(Rat) |
NCBI Taxa ID |
10116 |
Functional Description (View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 4 Position | Peptides | Source | References ( PMIDs ) |
---|
174 | LSKWRMMSLSQSRSY | curated | 23984901 | 411 | AFCDRRASSCSLTVI | PhosphoSitePlus | 22135298 | 412 | FCDRRASSCSLTVIR | PhosphoSitePlus | 22135298 | 414 | DRRASSCSLTVIRPL | PhosphoSitePlus | 22135298 |
|
Sequence (Fasta) | MNGDAICSAL PHIPYHKLAD LHYLSRGASG TVSSARHADW RVRVAVKHLH IHTPLLDSER 60 NDILREAEIL HKARFSYILP ILGICNEPEF LGIVTEYMPN GSLNELLHRK TEYPEIAWPL 120 RFRILHEIAL GVNYLHNMNP PLLHHDLKTQ NILLDNEFHV KIADFGLSKW RMMSLSQSRS 180 YKSAPEGGTI IYMPPENYEP GQKSRASVKH DIYSYAVIMW EVLSRKQPFE EVTNPLQIMY 240 SVSQGHRPNT SEENLPFDIP HRGLMISLIQ SGWAQNPDER PSFLKCLIEL EPVLRTFEDI 300 TFLEAVIQLK KSKIQSASST IHLCDKKMDL SLNIPASHPP QEESCGSSLL SRNAGSPGTS 360 RSLSAPQDKG FFHGGPQDCS SSKAYHCPGN HSWDGIISVS QEAAFCDRRA SSCSLTVIRP 420 LLVEKSSERP QPGIAQQWIQ SKREAIVSQM TEACLNQSLD ALLSRDLIMK EDYELISTKP 480 TRTAKVRQLL DTSDIQGEEF ARVIVQKLKD NKQMGLQPYP EVLLVSRTPS SNVLQNKTL
540 Fasta Sequence
>G3V783|Ripk2|Rattus norvegicus(Rat) MNGDAICSALPHIPYHKLADLHYLSRGASGTVSSARHADWRVRVAVKHLHIHTPLLDSERNDILREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPEIAWPLRFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSYKSAPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVIMWEVLSRKQPFEEVTNPLQIMYSVSQGHRPNTSEENLPFDIPHRGLMISLIQSGWAQNPDERPSFLKCLIELEPVLRTFEDITFLEAVIQLKKSKIQSASSTIHLCDKKMDLSLNIPASHPPQEESCGSSLLSRNAGSPGTSRSLSAPQDKGFFHGGPQDCSSSKAYHCPGNHSWDGIISVSQEAAFCDRRASSCSLTVIRPLLVEKSSERPQPGIAQQWIQSKREAIVSQMTEACLNQSLDALLSRDLIMKEDYELISTKPTRTAKVRQLLDTSDIQGEEFARVIVQKLKDNKQMGLQPYPEVLLVSRTPSSNVLQNKTL
|
Keyword |
KW-0067--ATP-binding KW-0175--Coiled coil KW-0181--Complete proteome KW-0547--Nucleotide-binding KW-1185--Reference proteome
|
Interpro |
IPR001315--CARD IPR011029--DEATH-like_dom IPR011009--Kinase-like_dom IPR000719--Prot_kinase_dom IPR017322--Rcpt-int_Ser/Thr_kinase-2 IPR001245--Ser-Thr/Tyr_kinase_cat_dom IPR008271--Ser/Thr_kinase_AS
|
PROSITE |
PS50209--CARD PS50011--PROTEIN_KINASE_DOM PS00108--PROTEIN_KINASE_ST
|
Pfam |
PF00619--CARD PF07714--Pkinase_Tyr
|
Gene Ontology |
GO:0005737--C:cytoplasm GO:0005856--C:cytoskeleton GO:0043234--C:protein complex GO:0031982--C:vesicle GO:0005524--F:ATP binding GO:0004674--F:protein serine/threonine kinase activity GO:0002250--P:adaptive immune response GO:0071223--P:cellular response to lipoteichoic acid GO:0071225--P:cellular response to muramyl dipeptide GO:0071224--P:cellular response to peptidoglycan GO:0050830--P:defense response to Gram-positive bacterium GO:0007249--P:I-kappaB kinase/NF-kappaB signaling GO:0031663--P:lipopolysaccharide-mediated signaling pathway GO:0070427--P:nucleotide-binding oligomerization domain containing 1 signaling pathway GO:0070431--P:nucleotide-binding oligomerization domain containing 2 signaling pathway GO:0046641--P:positive regulation of alpha-beta T cell proliferation GO:0043065--P:positive regulation of apoptotic process GO:0032722--P:positive regulation of chemokine production GO:0001961--P:positive regulation of cytokine-mediated signaling pathway GO:0070374--P:positive regulation of ERK1 and ERK2 cascade GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0033091--P:positive regulation of immature T cell proliferation GO:0032729--P:positive regulation of interferon-gamma production GO:0032743--P:positive regulation of interleukin-2 production GO:0032755--P:positive regulation of interleukin-6 production GO:0046330--P:positive regulation of JNK cascade GO:0051092--P:positive regulation of NF-kappaB transcription factor activity GO:0033138--P:positive regulation of peptidyl-serine phosphorylation GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation GO:0031398--P:positive regulation of protein ubiquitination GO:0045627--P:positive regulation of T-helper 1 cell differentiation GO:0032760--P:positive regulation of tumor necrosis factor production GO:0043330--P:response to exogenous dsRNA GO:0070555--P:response to interleukin-1 GO:0070671--P:response to interleukin-12 GO:0070673--P:response to interleukin-18 GO:0042098--P:T cell proliferation GO:0050852--P:T cell receptor signaling pathway GO:0034134--P:toll-like receptor 2 signaling pathway GO:0034142--P:toll-like receptor 4 signaling pathway
|