dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052176
Uniprot Accession G3V723; G3V723_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Phosphate regulating gene with homologies to endopeptidases on the X chromosome (Hypophosphatemia, vitamin D resistant rickets), isoform CRA_a
Protein Synonyms/Alias
Gene Name Phex
Gene Synonyms/Alias rCG_36426;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
7-MEAEAGSTMETGKGPhosphoSitePlus22135298
190RKFSLLQTLATFRGQPhosphoSitePlus;SysPTM 2.0;curated22135298; 16641100; 19366988; 22817900
193SLLQTLATFRGQYSNPhosphoSitePlus;SysPTM 2.0;curated22135298; 16641100; 19366988; 22817900
244DNTTEAKSYRDALYKPhosphoSitePlus;SysPTM 2.0;curated22135298; 16641100; 19366988; 22817900
250KSYRDALYKFMVDTAPhosphoSitePlus;SysPTM 2.0;curated22135298; 16641100; 19366988; 22817900
256LYKFMVDTAVLLGANPhosphoSitePlus;SysPTM 2.0;curated22135298; 16641100; 19366988; 22817900
264AVLLGANSSRAEHDMPhosphoSitePlus;SysPTM 2.0;curated22135298; 16641100; 19366988; 22817900
265VLLGANSSRAEHDMKPhosphoSitePlus;SysPTM 2.0;curated22135298; 16641100; 19366988; 22817900
Sequence
(Fasta)
MEAEAGSTME TGKGTNRGIR IALALFITGT LVLGTLLFLV SQGLLSFQAK QEYCLKPECI 60
EAAAAIMSKV NLSVDPCENF FRFACDGWIS NNPIPEDMPS YGVYPWLRHN VDLKLKALLE 120
KSVSRRRDTE AVQKAKILYS SCMNEKAIEK ADAKPLLHIL RHSPFRWPVL EANIGPEGVW 180
SERKFSLLQT LATFRGQYSN SVFIRLYVSP DDKASNEHIL KLDQATLSLA VREDFLDNTT 240
EAKSYRDALY KFMVDTAVLL GANSSRAEHD MKSVLRLEIK IAEIMIPHEN RTSEAMYNKM 300
NISELSAMIP QFDWLGYIKK VIDTRLYPHL KDIGPSENVV VRVPQYFKDL FRILGAERKK 360
TIANYLVWRM VYSRIPNLSR RFQYRWLEFS RVIQGTTTLL PQWDKCVNFI ESALPYVVGK 420
MFVNVHFQED KKEMMEELIE GVRWAFIDML EKENEWMDAG TKRKAQEKAR AVLAKVGYPE 480
FIMNDTYVNE DLKAIKFSES DYFGNVLQTR KYLAQSDFFW LRKAVPKTEW FTNPTTVNAF 540
YSASTNQIRF PAGELQKPFF WGTEYPRSLS YGAIGVIVGH EFTHGFDNNG RKYDKNGNLD 600
PWWSVDSEEK FKEKTKCMIN QYSNYYWKKA GLNVKGKRTL GENIADNGGL REAFRAYRKW 660
INDRRQGVEE PLLPGITFTN NQLFFLSYAH VRCNSYRPEA AREQVQIGAH SPPQFRVNGA 720
ISNFEEFQKA FNCPANSTMN RGADSCRLW
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR024079--MetalloPept_cat_dom
IPR000718--Peptidase_M13
IPR018497--Peptidase_M13_C
IPR008753--Peptidase_M13_N

PROSITE
Pfam

PF01431--Peptidase_M13
PF05649--Peptidase_M13_N

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005794--C:Golgi apparatus
GO:0016021--C:integral component of membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0004222--F:metalloendopeptidase activity
GO:0030282--P:bone mineralization
GO:0019637--P:organophosphate metabolic process