dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052156
Uniprot Accession G3V6N7; G3V6N7_RAT;
Genbank Protein ID NP_001103100.1;
Genbank Nucleotide ID NM_001109630.1;
Protein Name Protein Slc12a6
Protein Synonyms/Alias
Gene Name Slc12a6
Gene Synonyms/Alias rCG_27287;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 11
PositionPeptidesSourceReferences ( PMIDs )
32IPGLSDTSPDLSSRSPhosphoSitePlus22135298
47SSRVRFSSRESVPETPhosphoSitePlus22135298
50VRFSSRESVPETSRSPhosphoSitePlus22135298
96TEDPNQNSITGEHSQPhosphoSitePlus22135298
991SAYTYERTLMMEQRSPhosphoSitePlus22135298
1028RNSMLRLTSIGSDEDPhosphoSitePlus22135298
1029NSMLRLTSIGSDEDEPhosphoSitePlus;curated22135298; 23984901
1032LRLTSIGSDEDEETEPhosphoSitePlus;curated22135298; 23984901
1038GSDEDEETETYQEKVPhosphoSitePlus22135298
1040DEDEETETYQEKVHMPhosphoSitePlus22135298
1041EDEETETYQEKVHMTPhosphoSitePlus22135298
Sequence
(Fasta)		MHPPETTTKM SSVRFMVTPT KIDDIPGLSD TSPDLSSRSS SRVRFSSRES VPETSRSEPM 60
SELSGATTSL ATVALDPSSD RTSNPQDVTE DPNQNSITGE HSQLLDDGHK KARNAYLNNS 120
NYEEGDEYFD KNLALFEEEM DTRPKVSSLL NRMANYTNLT QGAKEHEEAE NITEGKKKPT 180
KSPQMGTFMG VYLPCLQNIF GVILFLRLTW VVGTAGVLQA FAIVLICCCC TMLTAISMSA 240
IATNGVVPAG GSYFMISRAL GPEFGGAVGL CFYLGTTFAA AMYILGAIEI FLVYIVPRAA 300
IFRSDDALKE SAAMLNNMRV YGTAFLVLMV LVVFIGVRYV NKFASLFLAC VIVSILAIYA 360
GAIKSSFAPP HFPVCMLGNR TLSSRHLDIC SKTKEVNNMT IPSKLWGFFC NSSQFFNATC 420
DEYFVHNNVT SIQGIPGLAS GIITENLWSN YLPKGEIIEK PSAKSSDVLG NLNHEYVLAD 480
ITTSFTLLVG IFFPSVTGIM AGSNRSGDLK DAQKSIPIGT ILAILTTSFV YLSNVVLFGA 540
CIEGVVLRDK FGDAVKGNLV VGTLSWPSPW VIVIGSFFST CGAGLQSLTG APRLLQAIAK 600
DNIIPFLRVF GHSKANGEPT WALLLTAAIA ELGILIASLD LVAPILSMFF LMCYLFVNLA 660
CALQTLLRTP HWRPRFRYYH WALSFMGMSI CLALMFISSW YYAIVAMVIA GMIYKYIEYQ 720
GAEKEWGDGI RGLSLSAARF ALLRLEEGPP HTKNWRPQLL VLLKLDEDLH VKHPRLLTFA 780
SQLKAGKGLT IVGSVIVGNF LENYGDALAA EQTIKHLMEA EKVKGFCQLV VAAKLKEGIS 840
HLIQSCGLGG MKHNTVVMGW PNGWRQSEDA RAWKTFIGTV RVTTAAHLAL LVAKNVSFFP 900
SNVEQFSEGN IDVWWIVHDG GMLMLLPFLL KQHKVWRKCS IRIFTVAQLE DNSIQMKKDL 960
ATFLYHLRIE AEVEVVEMHD SDISAYTYER TLMMEQRSQM LRHMRLSKTE RDREAQLVKD 1020
RNSMLRLTSI GSDEDEETET YQEKVHMTWT KDKYMASRGQ KVKSMEGFQD LLNMRPDQSN 1080
VRRMHTAVKL NEVIVNKSHE AKLVLLNMPG PPRNPEGDEN YMEFLEVLTE GLERVLLVRG 1140
GGSEVITIYS 1151
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR004841--AA-permease/SLC12A_dom
IPR030364--KCC3
IPR000076--KCL_cotranspt
IPR018491--SLC12_C
IPR004842--SLC12A_fam
PROSITE
Pfam

PF00324--AA_permease
PF03522--SLC12
Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0022820--F:potassium ion symporter activity
GO:0015379--F:potassium:chloride symporter activity
GO:0035827--F:rubidium ion transmembrane transporter activity
GO:0006884--P:cell volume homeostasis
GO:0071477--P:cellular hypotonic salinity response
GO:0055064--P:chloride ion homeostasis
GO:1902476--P:chloride transmembrane transport
GO:0055075--P:potassium ion homeostasis
GO:0010107--P:potassium ion import