dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052153
Uniprot Accession G3V6L2; G3V6L2_RAT;
Genbank Protein ID XP_345901.4;
Genbank Nucleotide ID XM_345900.7;
Protein Name Protein Nek2
Protein Synonyms/Alias
Gene Name Nek2l1
Gene Synonyms/Alias Nek2;rCG_20225;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
175HDTSFAKTFVGTPYYPhosphoSitePlus;curated22135298; 22817900
179FAKTFVGTPYYMSPEPhosphoSitePlus22135298
184VGTPYYMSPEQISRLPhosphoSitePlus22135298
300PSKLQDSSPVLSELKPhosphoSitePlus22135298
Sequence
(Fasta)
MPSRVEDYEV LHSIGTGSYG RCQKIRRKSD GKILVWKELD YGSMTEVEKQ MLVSEVNLLR 60
ELKHPNIVRY YDRIIDRTNT TLYIVMEYCE GGDLASVITK GTKDRQYLEE EFVLRVMTQL 120
TLALKECHRR SDGGHTVLHR DLKPANVFLD SKHNVKLGDF GLARILNHDT SFAKTFVGTP 180
YYMSPEQISR LSYNEKSDIW SLGCLLYELC ALMPPFTAFN QKELAGKIRE GRFRRIPYRY 240
SDGLNDLITR MLNLKDYHRP SVEEILESPL IADLVAEEQR RNLERRGRRS GEPSKLQDSS 300
PVLSELKLKE RQLQDRERAL RAREDSLEQK ERELCIRERL AEDKLARAES LLKNYSLLKE 360
HRLLCLAGGS ELDLPSSALK KKVHFHGESK ENTTRSENSE SQLAKSKCRD LKKRLHAAQL 420
RAQALSDIEK NYQLKSRQIL GMR 444
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

Gene Ontology

GO:0005813--C:centrosome
GO:0000794--C:condensed nuclear chromosome
GO:0005737--C:cytoplasm
GO:0045171--C:intercellular bridge
GO:0000776--C:kinetochore
GO:0030496--C:midbody
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0001824--P:blastocyst development
GO:0051299--P:centrosome separation
GO:0007059--P:chromosome segregation
GO:0007017--P:microtubule-based process
GO:0000070--P:mitotic sister chromatid segregation
GO:0090307--P:mitotic spindle assembly
GO:1903126--P:negative regulation of centriole-centriole cohesion
GO:0043392--P:negative regulation of DNA binding
GO:0046777--P:protein autophosphorylation
GO:0006468--P:protein phosphorylation
GO:0051988--P:regulation of attachment of spindle microtubules to kinetochore