| Tag |
Content |
| dbPAF ID |
dbPAF-0052152 |
| Uniprot Accession |
G3V6L1; G3V6L1_RAT;
|
| Genbank Protein ID |
NP_001124008.1; XP_008763671.1;
|
| Genbank Nucleotide ID |
NM_001130536.1; XM_008765449.1;
|
| Protein Name |
Frizzled homolog 6 (Drosophila) |
| Protein Synonyms/Alias |
|
| Gene Name |
Fzd6 |
| Gene Synonyms/Alias |
rCG_59567; |
| Organism |
Rattus norvegicus(Rat) |
| NCBI Taxa ID |
10116 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 1 |
Sequence
(Fasta) | MEASPFLSAC ILLPLIRGHS LFTCEPITVP RCMKMAYNMT FFPNLMGHYD QGIAAVEMEH 60
FLPLANLECS PNIEMFLCQA FVPTCTEQID VVSPCRKLCE KILSDCQKLM DTFGIRWPEE 120
LECHRLPYCD GAVPVTSDPH TELFGPQKKT DQVPRDIGFW CPKHLRTSGD QGYRFLGIDQ 180
CAPPCPNMYF KSDELDFAKS FIGIVSIFCL CATLFTFLTF LIDVRRFRYP ERPIIYYSVC 240
YSIVSLMYFV GFLLGNSTAC NKADEKLELG NTVVLGSKNK ACSVVFMFLY FFTMAGTVWW 300
VILTITWFLA AGRKWSCEAI EQKAVWFHAV AWGMPGFLTV MLLAMNKVEG DNISGVCFVG 360
LYDLDASRYF VLLPLCLCVF VGLSLLLAGI ISLNHVRQVI QHDGRNQEKL KKFMIRIGVF 420
SGLYLVPLVT LLGCYVYELV NRVTWEMTWF SDHCHQYRIP CPYQANPKAR PELALFMIKY 480
LMTLIVGISA VFWVGSKKTC TEWAGFCKRN RKRDPISESR RVLQESCEFF LKHNSKVRHK 540
KKHGKPGSHK LKVISKSMGT STGVTTDHGT SAVAIADHDY LGQETSAEVQ TSPEASLKEG 600
RADRANTPRA KGPDCGEPAS TAASNSKFSG DQIDRKSRAG SVKEKSSVSE GAPSEGRVSP 660
KGVPGTGLME CTLQIPSSPE PNSLKGSTSL LVRSASGTRK EQGAGGHSDT
711Fasta Sequence
>G3V6L1|Fzd6|Rattus norvegicus(Rat)
MEASPFLSACILLPLIRGHSLFTCEPITVPRCMKMAYNMTFFPNLMGHYDQGIAAVEMEHFLPLANLECSPNIEMFLCQAFVPTCTEQIDVVSPCRKLCEKILSDCQKLMDTFGIRWPEELECHRLPYCDGAVPVTSDPHTELFGPQKKTDQVPRDIGFWCPKHLRTSGDQGYRFLGIDQCAPPCPNMYFKSDELDFAKSFIGIVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVCYSIVSLMYFVGFLLGNSTACNKADEKLELGNTVVLGSKNKACSVVFMFLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQKAVWFHAVAWGMPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYELVNRVTWEMTWFSDHCHQYRIPCPYQANPKARPELALFMIKYLMTLIVGISAVFWVGSKKTCTEWAGFCKRNRKRDPISESRRVLQESCEFFLKHNSKVRHKKKHGKPGSHKLKVISKSMGTSTGVTTDHGTSAVAIADHDYLGQETSAEVQTSPEASLKEGRADRANTPRAKGPDCGEPASTAASNSKFSGDQIDRKSRAGSVKEKSSVSEGAPSEGRVSPKGVPGTGLMECTLQIPSSPEPNSLKGSTSLLVRSASGTRKEQGAGGHSDT
|
| Keyword |
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-1015--Disulfide bond
KW-0472--Membrane
KW-0675--Receptor
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0879--Wnt signaling pathway
|
| Interpro |
IPR000539--Frizzled
IPR015526--Frizzled/SFRP
IPR020067--Frizzled_dom
IPR026543--FZD6
IPR017981--GPCR_2-like
|
| PROSITE |
PS50038--FZ
PS50261--G_PROTEIN_RECEP_F2_4
|
| Pfam |
PF01534--Frizzled
PF01392--Fz
|
| Gene Ontology |
GO:0045177--C:apical part of cell
GO:0016327--C:apicolateral plasma membrane
GO:0016021--C:integral component of membrane
GO:0004930--F:G-protein coupled receptor activity
GO:0042813--F:Wnt-activated receptor activity
GO:0017147--F:Wnt-protein binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0033278--P:cell proliferation in midbrain
GO:0035880--P:embryonic nail plate morphogenesis
GO:0001736--P:establishment of planar polarity
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0001942--P:hair follicle development
GO:0042472--P:inner ear morphogenesis
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0001843--P:neural tube closure
GO:0035567--P:non-canonical Wnt signaling pathway
GO:0030168--P:platelet activation
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway
|
