dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0052074 |
| Uniprot Accession | G3UYX5; RGS22_MOUSE; |
| Genbank Protein ID | NP_001182677.1; XP_011243672.1; XP_011243673.1; XP_011243674.1; XP_011243675.1; |
| Genbank Nucleotide ID | NM_001195748.1; XM_011245370.1; XM_011245371.1; XM_011245372.1; XM_011245373.1; |
| Protein Name | Regulator of G-protein signaling 22 |
| Protein Synonyms/Alias | |
| Gene Name | Rgs22 |
| Gene Synonyms/Alias | |
| Organism | Mus musculus(Mouse) |
| NCBI Taxa ID | 10090 |
| Functional Description (View all) |
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. |
| Phosphorylation Sites |
dbPAF PTMs: 5 |
| Sequence (Fasta) | MPEKRLSAEP PEVTEEEFEN YLATDNFLVD YFNEFLSLPT FPEAIRFNVD YGVFEVVNDA 60 PQLLEKQLKK ILQNQQPRNP IYDVVRKGKS DSKSTQKSVP CEDEAINVNY SIMCLKREQG 120 INWIKRERLP AFLESDCYFE YRLAKLISQA TWSSTGMNFI VGTNFTPWIL RRPPAPPPPS 180 TDEDNYMIMK KFYVSLGQAS YTQTKDWFTL AKESENTVTM ASLPCCIPHH QTASPVIATA 240 SEIFDDGVHP RTIKSLSKSS KAVSELDEEE EGSISMKDSP SQALLRVYLE KKGGKERNLT 300 LHFSSVEEFL DAYIIFILRE AIQHITGQSL SDTPEYINYY KVSHVIFDKV PPVPSNKAIV 360 SPPVEMVEEI SKDRLENVSL SSESESIGPE SRADWCISHR TYDIGNRREF ERFKKFLKGT 420 LGERYWWLWM DIERLKVLKD PERHQRHLEK MKKCYLVSSG ERYLSAEILS KFKLLHGSRW 480 TADHLKNIQA EVLKPLLLYW APRFCVTHSA SAKNASTELK FWRLRQEKPR KDVDPFPQMA 540 TLLPLRPKSC IPQTPEVQGE EINLFQPSKF KKLSKINAGT QQLGRSEPLN AVSSKDGGLE 600 KGSKRLPEST TVVRLTSFTD ISECLKPQLE RKYTYTEEHN VKTVSNVGAL GGFDMENLLQ 660 SLYVENRAGF FFTKFCENSG NKLWKHSVYF WFDLQAYHQL FYQETLQPFK VCKQAQYLFA 720 TYIAPSASFD IGLHQEGKKD IYMKIQPPFE DLFDTAEEFI LLSLLEPWTQ MVMSDKMAYK 780 KVELQEETRQ LDSACFRKLH ALHKETISKK AEDTTGYAMA KLSLSDVSKQ TEYWLNVPEG 840 YKHFTFTDLL NNKLEFEHFR QFLESHSSSL DLMCWIDIEQ FRRIIFKDQK QREEKSIYIK 900 NKYLNKKYFF GPRSPASLHQ QNQIMLLSGG WGRILHEQLD ASVLVEIQKH VLNRLENVWL 960 PLFLSSEQFA SRQKIKTQMK DIADELLLQR HDRKIGVWKP VESKWISSSC EIIAFRKALL 1020 NPVIARQFQR FVALKGDLLE NGVLFWQEVQ KFKDLCHSHC DESIIHKKIT TIINCFINSY 1080 IPPALQIDIP VEQAQKILEH RKELGPYVFR EAQMTIFGVL FKFWPQFCEF RKNLTDEKIM 1140 SVLERRQEHK QKRKASDTEE DKAGKSGVKQ YASTTGSLTK PVLGSESLLV LQSYGRQPTW 1200 CYSKYIEALE QERILLKIQE EVERKMFTGT SSFTNLLKPS TGSALSLKKN VSLHSIQR 1259 |
| Keyword | KW-0175--Coiled coil |
| Interpro | IPR016137--RGS |
| PROSITE | PS50132--RGS |
| Pfam | PF00615--RGS |
| Gene Ontology | GO:0005737--C:cytoplasm |