dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052053
Uniprot Accession G3UW82; G3UW82_MOUSE;
Genbank Protein ID NP_001034634.2;
Genbank Nucleotide ID NM_001039545.2;
Protein Name MCG140437, isoform CRA_d
Protein Synonyms/Alias
Gene Name Myh2
Gene Synonyms/Alias mCG_140437;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 37 (View all)
PositionPeptidesSourceReferences ( PMIDs )
2------MSSDAEMAVcurated24723360
16VFGEAAPYLRKSEKEcurated20469934
404DLLKALCYPRVKVGNPhosphoSitePlus;SysPTM 2.022135298; 17242355; 19366988
413RVKVGNEYVTKGQTVPhosphoSitePlus22135298
415KVGNEYVTKGQTVEQPhosphoSitePlus22135298
649KGAKKKGSSFQTVSAPhosphoSitePlus;curated22135298; 22817900; 21183079
650GAKKKGSSFQTVSALPhosphoPep 2.019060867
749YIDSKKASEKLLGSIcurated21183079
955RKLEDECSELKKDIDPhosphoSitePlus;curated22135298; 22817900; 21183079
986ENKVKNLTEEMAGLDPhosphoSitePlus22135298
1013LQEAHQQTLDDLQAEPhosphoSitePlus22135298
1026AEEDKVNTLTKAKIKPhosphoSitePlus;curated22135298; 24723360
1044QVDDLEGSLEQEKKLPhosphoSitePlus;curated22135298; 21183079
1135EIEAERASRAKAEKQPhosphoSitePlus;curated22135298; 22817900; 21183079
1144AKAEKQRSDLSRELEPhosphoPep 2.019060867
1147EKQRSDLSRELEEISPhosphoPep 2.0;PhosphoSitePlus19060867; 22135298
1164LEEAGGATSAQIEMNcurated25338131
1206LRKKHADSVAELGEQPhosphoPep 2.0;PhosphoSitePlus;curated19060867; 22135298; 22817900; 21183079; 24723360
1244DLASNVETVSKAKGNPhosphoSitePlus22135298
1246ASNVETVSKAKGNLEPhosphoSitePlus22135298
Sequence
(Fasta)
MSSDAEMAVF GEAAPYLRKS EKERIEAQNR PFDAKTSVFV AEPKESFVKG TIQSKDAGKV 60
TVKTEAGATL TVKEDQIFPM NPPKYDKIED MAMMTHLHEP AVLYNLKERY AAWMIYTYSG 120
LFCVTVNPYK WLPVYNPEVV AAYRGKKRQE APPHIFSISD NAYQFMLTDR ENQSILITGE 180
SGAGKTVNTK RVIQYFATIA VTGDKKKEEA TSGKMQGTLE DQIISANPLL EAFGNAKTVR 240
NDNSSRFGKF IRIHFGTTGK LASADIETYL LEKSRVTFQL KAERSYHIFY QITSNKKPEL 300
IEMLLITTNP YDYPFVSQGE ISVASIDDQE ELMATDSAID ILGFTNDEKV SIYKLTGAVM 360
HYGNMKFKQK QREEQAEPDG TEVADKAAYL QGLNSADLLK ALCYPRVKVG NEYVTKGQTV 420
EQVTNAVGAL AKAMYEKMFL WMVTRINQQL DTKQPRQYFI GVLDIAGFEI FDFNSLEQLC 480
INFTNEKLQQ FFNHHMFVLE QEEYKKEGIE WTFIDFGMDL AACIELIEKP MGIFSILEEE 540
CMFPKATDTS FKNKLYEQHL GKSANFQKPK VVKGKAEAHF SLIHYAGTVD YNITGWLDKN 600
KDPLNETVVG LYQKSSVKTL AYLFSGAQTA EAEASSGGAA KKGAKKKGSS FQTVSALFRE 660
NLNKLMTNLR STHPHFVRCI IPNETKTPGA MEHELVLHQL RCNGVLEGIR ICRKGFPSRI 720
LYADFKQRYK VLNASAIPEG QYIDSKKASE KLLGSIDIDH TQYKFGHTKV FFKAGLLGLL 780
EEMRDDKLAQ LITRTQAMCR GFLARVEYQK MVERRESIFC IQYNIRAFMN VKHWPWMKLF 840
FKIKPLLKSA ETEKEMATMK EEFQKTKDDL AKSEAKRKEL EEKMVSLLKE KNDLQLQVQA 900
EAEGLADAEE RCDQLIKTKI QLEAKIKEVT ERAEDEEEIN AELTAKKRKL EDECSELKKD 960
IDDLELTLAK VEKEKHATEN KVKNLTEEMA GLDETIAKLT KEKKALQEAH QQTLDDLQAE 1020
EDKVNTLTKA KIKLEQQVDD LEGSLEQEKK LRMDLERAKR KLEGDLKLAQ ESIMDIENEK 1080
QQLDERLKKK EFEMSNLQSK IEDEQAIGIQ LQKKIKELQA RIEELEEEIE AERASRAKAE 1140
KQRSDLSREL EEISERLEEA GGATSAQIEM NKKREAEFQK MRRDLEEATL QHEATAATLR 1200
KKHADSVAEL GEQIDNLQRV KQKLEKEKSE MKMEIDDLAS NVETVSKAKG NLEKMCRTLE 1260
DQVSELKSKE EEQQRLINDL TTQRGRLQTE SGEFSRQLDE KEALVSQLSR GKQAFTQQIE 1320
ELKRQLEEEV KAKNALAHAL QSSRHDCDLL REQYEEEQES KAELQRALSK ANSEVAQWRT 1380
KYETDAIQRT EELEEAKKKL AQRLQAAEEH VEAVNAKCAS LEKTKQRLQN EVEDLMLDVE 1440
RTNAACAALD KKQRNFDKIL AEWKQKYEET HAELEASQKE ARSLGTELFK MKNAYEESLD 1500
QLETLKRENK NLQQEISDLT EQIAEGGKRI HELEKIKKQV EQEKCELQAA LEEAEASLEH 1560
EEGKILRIQL ELNQVKSEID RKIAEKDEEI DQLKRNHIRV VESMQSTLDA EIRSRNDAIR 1620
IKKKMEGDLN EMEIQLNHSN RMAAEALRNY RNTQGILKDT QLHLDDALRG QEDLKEQLAM 1680
VERRANLLQA EIEELRATLE QTERSRKIAE QELLDASERV QLLHTQNTSL INTKKKLETD 1740
ISQIQGEMED IVQEARNAEE KAKKAITDAA MMAEELKKEQ DTSAHLERMK KNMEQTVKDL 1800
QLRLDEAEQL ALKGGKKQIQ KLEARVRELE GEVESEQKRN AEAVKGLRKH ERRVKELTYQ 1860
TEEDRKNILR LQDLVDKLQA KVKSYKRQAE EAEEQSNTNL SKFRKIQHEL EEAEERADIA 1920
ESQVNKLRVK SREVHTKIIS EE 1943
Keyword

KW-0009--Actin-binding
KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0518--Myosin
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom
IPR001609--Myosin_head_motor_dom
IPR004009--Myosin_N
IPR002928--Myosin_tail
IPR027417--P-loop_NTPase

PROSITE

PS50096--IQ
PS51456--MYOSIN_MOTOR

Pfam

PF00063--Myosin_head
PF02736--Myosin_N
PF01576--Myosin_tail_1

Gene Ontology

GO:0031672--C:A band
GO:0005826--C:actomyosin contractile ring
GO:0005911--C:cell-cell junction
GO:0005794--C:Golgi apparatus
GO:0005859--C:muscle myosin complex
GO:0030016--C:myofibril
GO:0043234--C:protein complex
GO:0005524--F:ATP binding
GO:0003774--F:motor activity
GO:0070252--P:actin-mediated cell contraction
GO:0006936--P:muscle contraction
GO:0001778--P:plasma membrane repair
GO:0014823--P:response to activity