dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052046
Uniprot Accession G3UVW6; G3UVW6_MOUSE;
Genbank Protein ID NP_001240710.1;
Genbank Nucleotide ID NM_001253781.1;
Protein Name Prolactin receptor
Protein Synonyms/Alias
Gene Name Prlr
Gene Synonyms/Alias prlr;mCG_18319;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
281FDTHLLETGSPSKYKcurated23984901
Sequence
(Fasta)
MSSALAYMLL VLSISLLNGQ SPPGKPEIHK CRSPDKETFT CWWNPGSDGG LPTNYSLTYS 60
KEGEKNTYEC PDYKTSGPNS CFFSKQYTSI WKIYIITVNA TNEMGSSTSD PLYVDVTYIV 120
EPEPPRNLTL EVKQLKDKKT YLWVKWLPPT ITDVKTGWFT MEYEIRLKSE EADEWEIHFT 180
GHQTQFKVFD LYPGQKYLVQ TRCKPDHGYW SRWGQEKSIE IPNDFTLKDT TVWIIVAVLS 240
AVICLIMVWA VALKGYSMMT CIFPPVPGPK IKGFDTHLLE TGSPSKYKVD PRLALPGRFQ 300
KLDNEGELDY 311
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0675--Receptor
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003961--FN3_dom
IPR015152--Growth/epo_recpt_lig-bind
IPR013783--Ig-like_fold
IPR003528--Long_hematopoietin_rcpt_CS

PROSITE

PS50853--FN3
PS01352--HEMATOPO_REC_L_F1

Pfam

PF09067--EpoR_lig-bind

Gene Ontology

GO:0009986--C:cell surface
GO:0016021--C:integral component of membrane
GO:0005622--C:intracellular
GO:0017046--F:peptide hormone binding
GO:0004925--F:prolactin receptor activity
GO:0007171--P:activation of transmembrane receptor protein tyrosine kinase activity
GO:0007259--P:JAK-STAT cascade
GO:0007595--P:lactation
GO:0060749--P:mammary gland alveolus development
GO:0060644--P:mammary gland epithelial cell differentiation
GO:0061180--P:mammary gland epithelium development
GO:0038161--P:prolactin signaling pathway
GO:0060736--P:prostate gland growth
GO:0030155--P:regulation of cell adhesion
GO:0030856--P:regulation of epithelial cell differentiation