dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052044
Uniprot Accession G3UVV4; G3UVV4_MOUSE;
Genbank Protein ID XP_006513309.1;
Genbank Nucleotide ID XM_006513246.2;
Protein Name Hexokinase
Protein Synonyms/Alias
Gene Name Hk1
Gene Synonyms/Alias mCG_127656;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
8MDSEHCPSVPCGGAGPhosphoSitePlus22135298
Sequence
(Fasta)
MDSEHCPSVP CGGAGAWEAR IDKYLYAMRL SDEILIDILT RFKKEMKNGL SRDYNPTASV 60
KMLPTFVRSI PDGSEKGDFI ALDLGGSSFR ILRVQVNHEK SQNVSMESEV YDTPENIVHG 120
SGSQLFDHVA ECLGDFMEKR KIKDKKLPVG FTFSFPCRQS KIDEAVLITW TKRFKASGVE 180
GADVVKLLNK AIKKRGDYDA NIVAVVNDTV GTMMTCGYDD QQCEVGLIIG TGTNACYMEE 240
LRHIDLVEGD EGRMCINTEW GAFGDDGSLE DIRTEFDREL DRGSLNPGKQ LFEKMVSGMY 300
MGELVRLILV KMAKESLLFE GRITPELLTR GKFTTSDVAA IETDKEGVQN AKEILTRLGV 360
EPSHDDCVSV QHVCTIVSFR SANLVAATLG AILNRLRDNK GTPRLRTTVG VDGSLYKMHP 420
QYSRRFHKTL RRLVPDSDVR FLLSESGSGK GAAMVTAVAY RLAEQHRQIE ETLSHFRLSK 480
QALMEVKKKL RSEMEMGLRK ETNSRATVKM LPSYVRSIPD GTEHGDFLAL DLGGTNFRVL 540
LVKIRSGKKR TVEMHNKIYS IPLEIMQGTG DELFDHIVSC ISDFLDYMGI KGPRMPLGFT 600
FSFPCKQTSL DCGILITWTK GFKATDCVGH DVATLLRDAV KRREEFDLDV VAVVNDTVGT 660
MMTCAYEEPS CEIGLIVGTG SNACYMEEMK NVEMVEGNQG QMCINMEWGA FGDNGCLDDI 720
RTDFDKVVDE YSLNSGKQRF EKMISGMYLG EIVRNILIDF TKKGFLFRGQ ISEPLKTRGI 780
FETKFLSQIE SDRLALLQVR AILQQLGLNS TCDDSILVKT VCGVVSKRAA QLCGAGMAAV 840
VEKIRENRGL DHLNVTVGVD GTLYKLHPHF SRIMHQTVKE LSPKCTVSFL LSEDGSGKGA 900
ALITAVGVRL RGDPTNA 918
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0324--Glycolysis
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001312--Hexokinase
IPR019807--Hexokinase_BS
IPR022673--Hexokinase_C
IPR022672--Hexokinase_N

PROSITE

PS00378--HEXOKINASE_1
PS51748--HEXOKINASE_2

Pfam

PF00349--Hexokinase_1
PF03727--Hexokinase_2

Gene Ontology

GO:0005929--C:cilium
GO:0005829--C:cytosol
GO:0045121--C:membrane raft
GO:0005739--C:mitochondrion
GO:0097228--C:sperm principal piece
GO:0005524--F:ATP binding
GO:0008865--F:fructokinase activity
GO:0004340--F:glucokinase activity
GO:0005536--F:glucose binding
GO:0004396--F:hexokinase activity
GO:0019158--F:mannokinase activity
GO:0061621--P:canonical glycolysis
GO:0001678--P:cellular glucose homeostasis
GO:0072655--P:establishment of protein localization to mitochondrion
GO:0051156--P:glucose 6-phosphate metabolic process
GO:0006096--P:glycolytic process
GO:0072656--P:maintenance of protein location in mitochondrion
GO:1903599--P:positive regulation of mitophagy