dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052038
Uniprot Accession F8WJF7; F8WJF7_MOUSE;
Genbank Protein ID NP_001165584.1;
Genbank Nucleotide ID NM_001172113.1;
Protein Name E3 ubiquitin-protein ligase TRAF7
Protein Synonyms/Alias
Gene Name Traf7
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
36METTFGPTFSTVTTISysPTM 2.017242355; 19366988
39TFGPTFSTVTTITKASysPTM 2.017242355; 19366988
42PTFSTVTTITKADGTSysPTM 2.017242355; 19366988
58TYKQHRRTPSSSSTLPhosphoSitePlus22135298
60KQHRRTPSSSSTLAYPHOSIDA;PhosphoSitePlus;SysPTM 2.0;curated21081558; 22135298; 17242355; 19366988; 22817900; 21183079
62HRRTPSSSSTLAYSPPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 22817900; 21183079
63RRTPSSSSTLAYSPRPHOSIDA;PhosphoSitePlus;SysPTM 2.021081558; 22135298; 17242355; 19366988
Sequence
(Fasta)		MSSAKSARYD RFSGGPANLP SSDSSGTRME TTFGPTFSTV TTITKADGTG TYKQHRRTPS 60
SSSTLAYSPR DEEDGMPPIN TPRRSDSAIS VRSLHSESSM SLRSTFSLPE EEEEPEPLVF 120
AEQPSVKLCC QLCCSVFKDP VITTCGHTFC RRCALKSEKC PVDNAKLTVV VNNIAVAEQI 180
GELFIHCRHG CHAAGTGKPG VFEVDPRGCP FTIKLSARKD HESSCDYRPV RCPNNPSCPP 240
LLKMNLEAHL KECEHIKCPH SKYGCTFIGN QDTYETHLET CRFEGLKEFL QQTDDRFHEM 300
HVALAQKDQE IAFLRSMLGK LSEKIDQLEK SLELKFDVLD ENQSKLSEDL MEFRRDASML 360
NDELSHINAR LNMGILGSYD PQQIFKCKGT FVGHQGPVWC LCVYSMGDLL FSGSSDKTIK 420
VWDTCTTYKC QKTLEGHDGI VLALCIQGCK LYSGSADCTI IVWDIQNLQK VNTIRAHDNP 480
VCTLVSSHNM LFSGSLKAIK VWDIVGTELK LKKELTGLNH WVRALVAAQS YLYSGSYQTI 540
KIWDIRTLDC IHVLQTSGGS VYSIAVTNHH IVCGTYENLI HVWDIESKEQ VRTLTGHVGT 600
VYALAVISTP DQTKVFSASY DRSLRVWSMD NMICTQTLLR HQGSVTALAV SRGRLFSGAV 660
DSTVKVWTC
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013323--SIAH-type
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF
Pfam

PF00400--WD40
PF00097--zf-C3HC4
Gene Ontology

GO:0005829--C:cytosol
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0000151--C:ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0000185--P:activation of MAPKKK activity
GO:0006915--P:apoptotic process
GO:0071354--P:cellular response to interleukin-6
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:2001235--P:positive regulation of apoptotic signaling pathway
GO:0043410--P:positive regulation of MAPK cascade
GO:0033235--P:positive regulation of protein sumoylation
GO:0016567--P:protein ubiquitination
GO:0032880--P:regulation of protein localization