| Tag |
Content |
| dbPAF ID |
dbPAF-0052034 |
| Uniprot Accession |
F8WIS9; F8WIS9_MOUSE;
|
| Genbank Protein ID |
XP_006525604.1;
|
| Genbank Nucleotide ID |
XM_006525541.2;
|
| Protein Name |
Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| Protein Synonyms/Alias |
|
| Gene Name |
Camk2a |
| Gene Synonyms/Alias |
|
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MATITCTRFT EEYQLFEELG KGAFSVVRRC VKVLAGQEYA AKIINTKKLS ARDHQKLERE 60
ARICRLLKHP NIVRLHDSIS EEGHHYLIFD LVTGGELFED IVAREYYSEA DASHCIQQIL 120
EAVLHCHQMG VVHRDLKPEN LLLASKLKGA AVKLADFGLA IEVEGEQQAW FGFAGTPGYL 180
SPEVLRKDPY GKPVDLWACG VILYILLVGY PPFWDEDQHR LYQQIKAGAY DFPSPEWDTV 240
TPEAKDLINK MLTINPSKRI TAAEALKHPW ISHRSTVASC MHRQETVDCL KKFNARRKLK 300
GAILTTMLAT RNFSGGKSGG NKKNDGVKKR KSSSSVQLME SSESTNTTIE DEDTKVRKQE 360
IIKVTEQLIE AISNGDFESY TKMCDPGMTA FEPEALGNLV EGLDFHRFYF ENLWSRNSKP 420
VHTTILNPHI HLMGDESACI AYIRITQYLD AGGIPRTAQS EETRVWHRRD GKWQIVHFHR 480
SGAPSVLPH
Fasta Sequence
>F8WIS9|Camk2a|Mus musculus(Mouse)
MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH
|
| Keyword |
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
|
| Interpro |
IPR020636--Ca/CaM-dep_Ca-dep_prot_Kinase
IPR013543--Ca/CaM-dep_prot_kinase-assoc
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
|
| PROSITE |
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
|
| Pfam |
PF08332--CaMKII_AD
PF00069--Pkinase
|
| Gene Ontology |
GO:0005739--C:mitochondrion
GO:0097481--C:neuronal postsynaptic density
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0005516--F:calmodulin binding
GO:0004683--F:calmodulin-dependent protein kinase activity
GO:0035254--F:glutamate receptor binding
GO:0016301--F:kinase activity
GO:0042803--F:protein homodimerization activity
GO:0004674--F:protein serine/threonine kinase activity
GO:0038166--P:angiotensin-activated signaling pathway
GO:0006816--P:calcium ion transport
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0018105--P:peptidyl-serine phosphorylation
GO:0051928--P:positive regulation of calcium ion transport
GO:0010666--P:positive regulation of cardiac muscle cell apoptotic process
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046777--P:protein autophosphorylation
GO:0006468--P:protein phosphorylation
GO:1902108--P:regulation of mitochondrial membrane permeability involved in apoptotic process
GO:0048168--P:regulation of neuronal synaptic plasticity
GO:0046928--P:regulation of neurotransmitter secretion
GO:0002931--P:response to ischemia
|
