dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0052032
Uniprot Accession F8WIJ0; F8WIJ0_MOUSE;
Genbank Protein ID NP_001240733.1;
Genbank Nucleotide ID NM_001253804.1;
Protein Name Solute carrier family 12 member 4
Protein Synonyms/Alias
Gene Name Slc12a4
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
37ERAEREDSDGEGQGNcurated23684622
Sequence
(Fasta)
MPHFTVVPVD GPRRGDYDNL EGLSWVDYGE RAEREDSDGE GQGNHRENSP FLCPLDASRG 60
NDYYDRNLAL FEEELDIRPK VSSLLGKLVS YTNLTQGAKE HEEAESGEGG RRRAAKAPSM 120
GTLMGVYLPC LQNIFGVILF LRLTWMVGTA GVLQALLIVL ICCCCTLLTA ISMSAIATNG 180
VVPAGGSYFM ISRSLGPEFG GAVGLCFYLG TTFAAAMYIL GAIEILLTYI APPAAIFYPS 240
GTHDMSSATL NNMRVYGTIF LTLMTLVVFV GVKYVNKFAS LFLACVIISI LSIYAGGIKS 300
IFDPPVFPVC MLGNRTLSRD QFDICAKTVV VDNETVATRL WTFFCHSPNL TADSCDPYFL 360
LNNVTEIPGI PGAAAGVLQE NLWSAYLEKG EVVEKHGLPS TDTLGLKESL SLYVVADIAT 420
SFTVLVGIFF PSVTGIMAGS NRSGDLRDAQ KSIPVGTILA IVTTSLVYFS SVILFGACIE 480
GVVLRDKYGD GVSRNLVVGT LAWPSPWVIV VGSFFSTCGA GLQSLTGAPR LLQAIAKDNI 540
IPFLRVFGHG KANGEPTWAL LLTALIAELG ILIASLDMVA PILSMFFLMC YLFVNLACAV 600
QTLLRTPNWR PRFKYYHWTL SFLGMSLCLA LMFVSSWYYA LVAMLIAGMI YKYIEYQGAE 660
KEWGDGIRGL SLSAARYALL RLEEGPPHTK NWRPQLLVLL KLDEDLHVKY PRLLTFASQL 720
KAGKGLTIVG SVIQGSFLES YGEAQAAEQT IKNMMDIEKV KGFCQVVVAS KVREGLAHLI 780
QSCGLGGMRH NSVVLGWPYG WRQSEDPRAW KTFIDTVRCT TAAHLALLVP KNIAFYPSNH 840
ERYLDGHIDV WWIVHDGGML MLLPFLLRQH KVWKKCRMRI FTVAQMDDNS IQMKKDLAIF 900
LYHLRLEAEV EVVEMHNSDI SAYTYERTLM MEQRSQMLRQ MRLTKTERDR EAQLVKDRHS 960
ALRLESLYSD EEEESVAGAD KIQMTWTRDK YMAEPWDPSH APDNFRELVH IKPDQSNVRR 1020
MHTAVKLNEV IVTRSHDARL VLLNMPGPPK NSEGDENYME FLEVLTEGLE RVLLVRGGGR 1080
EVITIYS 1088
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR004841--AA-permease/SLC12A_dom
IPR000622--KCC1
IPR000076--KCL_cotranspt
IPR018491--SLC12_C
IPR004842--SLC12A_fam

PROSITE
Pfam

PF00324--AA_permease
PF03522--SLC12

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0005765--C:lysosomal membrane
GO:0022820--F:potassium ion symporter activity
GO:0015379--F:potassium:chloride symporter activity
GO:0019901--F:protein kinase binding
GO:0006884--P:cell volume homeostasis
GO:0055064--P:chloride ion homeostasis
GO:1902476--P:chloride transmembrane transport
GO:0055075--P:potassium ion homeostasis
GO:0010107--P:potassium ion import
GO:0007268--P:synaptic transmission