| Tag |
Content |
| dbPAF ID |
dbPAF-0051963 |
| Uniprot Accession |
F8VQL9; F8VQL9_MOUSE;
|
| Genbank Protein ID |
XP_011239130.1;
|
| Genbank Nucleotide ID |
XM_011240828.1;
|
| Protein Name |
Nuclear receptor corepressor 2 |
| Protein Synonyms/Alias |
|
| Gene Name |
Ncor2 |
| Gene Synonyms/Alias |
|
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MSGSTQPVAQ TWRAAEPRYP PHGISYPVQI ARSHTDVGLL EYQHHPRDYT SHLSPGSIIQ 60
PQRRRPSLLS EFQPGSERSQ ELHLRPESRT FLPELGKPDI EFTESKRPRL ELLPDTLLRP 120
SPLLATGQPS GSEDLTKDRS LAGKLEPVSP PSPPHADPEL ELAPSRLSKE ELIQNMDRVD 180
REITMVEQQI SKLKKKQQQL EEEAAKPPEP EKPVSPPPIE SKHRSLVQII YDENRKKAEA 240
AHRILEGLGP QVELPLYNQP SDTRQYHENI KINQAMRKKL ILYFKRRNHA RKQWEQRFCQ 300
RYDQLMEAWE KKVERIENNP RRRAKESKVR EYYEKQFPEI RKQRELQERM QSRVGQRGSG 360
LSMSAARSEH EVSEIIDGLS EQENLEKQMR QLAVIPPMLY DADQQRIKFI NMNGLMDDPM 420
KVYKDRQVTN MWSEQERDTF REKFMQHPKN FGLIASFLER KTVAECVLYY YLTKKNENYK 480
SLVRRSYRRR GKSQQQQQQQ QQQQQQQMAR SSQEEKEEKE KEKEADKEEE KQDAENEKEE 540
LSKEKTDDTS GEDNDEKEAV ASKGRKTANS QGRRKGRITR SMANEANHEE TATPQQSSEL 600
ASMEMNESSR WTEEEMETAK KGLLEHGRNW SAIARMVGSK TVSQCKNFYF NYKKRQNLDE 660
ILQQHKLKME KERNARRKKK KTPAAASEET AFPPAAEDEE MEASGASANE EELAEEAEAS 720
QASGNEVPRV GECSGPAAVN NSSDTESVPS PRSEATKDTG PKPTGTEALP AATQPPVPPP 780
EEPAVAPAEP SPVPDASGPP SPEPSPSPAA PPATVDKDEQ EAPAAPAPQT EDAKEQKSEA 840
EEIDVGKPEE PEASEEPPES VKSDHKEETE EEPEDKAKGT EAIETVSEAP LKVEEAGSKA 900
AVTKGSSSGA TQDSDSSATC SADEVDEPEG GDKGRLLSPR PSLLTPAGDP RASTSPQKPL 960
DLKQLKQRAA AIPPIVTKVH EPPREDTVPP KPVPPVPPPT QHLQPEGDVS QQSGGSPRGK 1020
SRSPVPPAEK EAEKPAFFPA FPTEGPKLPT EPPRWSSGLP FPIPPREVIK TSPHAADPSA 1080
FSYTPPGHPL PLGLHDSARP VLPRPPISNP PPLISSAKHP GVLERQLGAI SQQGMSVQLR 1140
VPHSEHAKAP MGPLTMGLPL AVDPKKLAPF SGVKQEQLSP RGQAGPPESL GVPTAQETSV 1200
LRGTALGSAT SGSITKGLPS TRAADGPSYR GSITHGTPAD VLYKGTISRI VGEDSPSRLD 1260
RAREDTLPKG HVIYEGKKGH VLSYEGGMSV SQCSKEDGRS SSGPPHETAA PKRTYDMMEG 1320
RVGRTVTSAS IEGLMGRAIP EQHSPHLKEQ HHIRGSITQG IPRSYVEAQE DYLRREAKLL 1380
KREGTPPPPP PPRDLTETYK PRPLDPLGPL KLKPTHEGVV ATVKEAGRSI HEIPREELRR 1440
TPELPLAPRP LKEGSITQGT PLKYDSGAPS TGTKKHDVRS IIGSPGRPFP ALHPLDIMAD 1500
ARALERACYE ESLKSRSGTS SGAGGSITRG APVVVPELGK PRQSPLTYED HGAPFTSHLP 1560
RGSPVTTREP TPRLQEGSLL SSKASQDRKL TSTPREIAKS PHSTVPEHHP HPISPYEHLL 1620
RGVTGVDLYR GHIPLAFDPT SIPRGIPLEA AAAAYYLPRH LAPSPTYPHL YPPYLIRGYP 1680
DTAALENRQT IINDYITSQQ MHHNAASAMA QRADMLRGLS PRESSLALNY AAGPRGIIDL 1740
SQVPHLPVLV PPTPGTPATA IDRLAYLPTA PPPFSSRHSS SPLSPGGPTH LAKPTATSSS 1800
ERERERERER DKSILTSTTT VEHAPIWRPG TEQSSGAGGS SRPASHTHQH SPISPRTQDA 1860
LQQRPSVLHN TSMKGVVTSV EPGTPTVLRW ARSTSTSSPV RPAATFPPAT HCPLGGTLEG 1920
VYPTLMEPVL LPKETSRVAR PERPRVDAGH AFLTKPPARE PASSPSKSSE PRSLAPPSSS 1980
HTAIARTPAK NLAPHHASPD PPAPTSASDL HREKTQSKPF SIQELELRSL GYHSGAGYSP 2040
DGVEPISPVS SPSLTHDKGL SKPLEELEKS HLEGELRHKQ PGPMKLSAEA AHLPHLRPLP 2100
ESQPSSSPLL QTAPGIKGHQ RVVTLAQHIS EVITQDYTRH HPQQLSGPLP APLYSFPGAS 2160
CPVLDLRRPP SDLYLPPPDH GTPARGSPHS EGGKRSPEPS KTSVLGSSED AIEPVSPPEG 2220
MTEPGHARST AYPLLYRDGE QGEPRMGSKS PGNTSQPPAF FSKLTESNSA MVKSKKQEIN 2280
KKLNTHNRNE PEYNIGQPGT EIFNMPAITG AGLMTCRSQA VQEHASTNMG LEAIIRKALM 2340
GKYDQWEEPP PLGANAFNPL NASASLPAAA MPITTADGRS DHALTSPGGG GKAKVSGRPS 2400
SRKAKSPAPG LASGDRPPSV SSVHSEGDCN RRTPLTNRVW EDRPSSAGST PFPYNPLIMR 2460
LQAGVMASPP PPGLAAGSGP LAGPHHAWDE EPKPLLCSQY ETLSDSE
2508Fasta Sequence
>F8VQL9|Ncor2|Mus musculus(Mouse)
MSGSTQPVAQTWRAAEPRYPPHGISYPVQIARSHTDVGLLEYQHHPRDYTSHLSPGSIIQPQRRRPSLLSEFQPGSERSQELHLRPESRTFLPELGKPDIEFTESKRPRLELLPDTLLRPSPLLATGQPSGSEDLTKDRSLAGKLEPVSPPSPPHADPELELAPSRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQRFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMDDPMKVYKDRQVTNMWSEQERDTFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQMARSSQEEKEEKEKEKEADKEEEKQDAENEKEELSKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANHEETATPQQSSELASMEMNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKTPAAASEETAFPPAAEDEEMEASGASANEEELAEEAEASQASGNEVPRVGECSGPAAVNNSSDTESVPSPRSEATKDTGPKPTGTEALPAATQPPVPPPEEPAVAPAEPSPVPDASGPPSPEPSPSPAAPPATVDKDEQEAPAAPAPQTEDAKEQKSEAEEIDVGKPEEPEASEEPPESVKSDHKEETEEEPEDKAKGTEAIETVSEAPLKVEEAGSKAAVTKGSSSGATQDSDSSATCSADEVDEPEGGDKGRLLSPRPSLLTPAGDPRASTSPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDTVPPKPVPPVPPPTQHLQPEGDVSQQSGGSPRGKSRSPVPPAEKEAEKPAFFPAFPTEGPKLPTEPPRWSSGLPFPIPPREVIKTSPHAADPSAFSYTPPGHPLPLGLHDSARPVLPRPPISNPPPLISSAKHPGVLERQLGAISQQGMSVQLRVPHSEHAKAPMGPLTMGLPLAVDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQETSVLRGTALGSATSGSITKGLPSTRAADGPSYRGSITHGTPADVLYKGTISRIVGEDSPSRLDRAREDTLPKGHVIYEGKKGHVLSYEGGMSVSQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRTVTSASIEGLMGRAIPEQHSPHLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKREGTPPPPPPPRDLTETYKPRPLDPLGPLKLKPTHEGVVATVKEAGRSIHEIPREELRRTPELPLAPRPLKEGSITQGTPLKYDSGAPSTGTKKHDVRSIIGSPGRPFPALHPLDIMADARALERACYEESLKSRSGTSSGAGGSITRGAPVVVPELGKPRQSPLTYEDHGAPFTSHLPRGSPVTTREPTPRLQEGSLLSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRGVTGVDLYRGHIPLAFDPTSIPRGIPLEAAAAAYYLPRHLAPSPTYPHLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHNAASAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAIDRLAYLPTAPPPFSSRHSSSPLSPGGPTHLAKPTATSSSERERERERERDKSILTSTTTVEHAPIWRPGTEQSSGAGGSSRPASHTHQHSPISPRTQDALQQRPSVLHNTSMKGVVTSVEPGTPTVLRWARSTSTSSPVRPAATFPPATHCPLGGTLEGVYPTLMEPVLLPKETSRVARPERPRVDAGHAFLTKPPAREPASSPSKSSEPRSLAPPSSSHTAIARTPAKNLAPHHASPDPPAPTSASDLHREKTQSKPFSIQELELRSLGYHSGAGYSPDGVEPISPVSSPSLTHDKGLSKPLEELEKSHLEGELRHKQPGPMKLSAEAAHLPHLRPLPESQPSSSPLLQTAPGIKGHQRVVTLAQHISEVITQDYTRHHPQQLSGPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGTPARGSPHSEGGKRSPEPSKTSVLGSSEDAIEPVSPPEGMTEPGHARSTAYPLLYRDGEQGEPRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNIGQPGTEIFNMPAITGAGLMTCRSQAVQEHASTNMGLEAIIRKALMGKYDQWEEPPPLGANAFNPLNASASLPAAAMPITTADGRSDHALTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLAAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE
|
| Keyword |
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
|
| Interpro |
IPR009057--Homeodomain-like
IPR031557--N-CoR_GPS2_interact
IPR001005--SANT/Myb
IPR017884--SANT_dom
|
| PROSITE |
PS51293--SANT
|
| Pfam |
PF15784--GPS2_interact
PF00249--Myb_DNA-binding
|
| Gene Ontology |
GO:0000118--C:histone deacetylase complex
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0017053--C:transcriptional repressor complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0042826--F:histone deacetylase binding
GO:0016922--F:ligand-dependent nuclear receptor binding
GO:0005112--F:Notch binding
GO:0047485--F:protein N-terminus binding
GO:0043565--F:sequence-specific DNA binding
GO:0003714--F:transcription corepressor activity
GO:0008134--F:transcription factor binding
GO:0021846--P:cell proliferation in forebrain
GO:0030900--P:forebrain development
GO:0042593--P:glucose homeostasis
GO:0003007--P:heart morphogenesis
GO:0001701--P:in utero embryonic development
GO:0045599--P:negative regulation of fat cell differentiation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0090312--P:positive regulation of protein deacetylation
GO:0072365--P:regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter
GO:0021537--P:telencephalon development
GO:0060509--P:Type I pneumocyte differentiation
GO:0050872--P:white fat cell differentiation
|
