dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0051961
Uniprot Accession F8VQK3; F8VQK3_MOUSE;
Genbank Protein ID NP_001028494.1;
Genbank Nucleotide ID NM_001033322.2;
Protein Name Protein Gucy1a2
Protein Synonyms/Alias
Gene Name Gucy1a2
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 12
PositionPeptidesSourceReferences ( PMIDs )
7-MSRRKISSESFSSLPhosphoSitePlus;curated22135298; 22817900; 21183079
8MSRRKISSESFSSLSPhosphoSitePlus;curated22135298; 22817900; 21183079
10RRKISSESFSSLSSDPhosphoSitePlus;curated22135298; 22817900; 21183079
12KISSESFSSLSSDYLPhosphoSitePlus;curated22135298; 22817900; 21183079
13ISSESFSSLSSDYLEPhosphoSitePlus;curated22135298; 22817900; 21183079
15SESFSSLSSDYLETSPhosphoSitePlus;curated22135298; 22817900; 21183079
22SSDYLETSPEEEGECPHOSIDA;PhosphoSitePlus21081558; 22135298
41LCWNGSRSPPGPPGSPhosphoSitePlus;curated22135298; 22817900; 21183079
669QLLKREDSFTFIPRSPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21183079
710PPKPSLSSSRIKKVSPhosphoSitePlus22135298
711PKPSLSSSRIKKVSYPhosphoSitePlus22135298
717SSRIKKVSYNIGTMFPhosphoSitePlus;curated22135298; 21183079
Sequence
(Fasta)		MSRRKISSES FSSLSSDYLE TSPEEEGECP LSRLCWNGSR SPPGPPGSRE AAKAATSAPA 60
ASAAAASAAV AAEYKRAQRR GRVNLDSLGE SISLLTAPLP QTIHMTLKRT LQYYEHQVIG 120
YRDAEKNFHN ISKRCSYADH SNKEEIEDVS GILQCTANVL GLQFQEIQER FGEEFFKICF 180
DENERVLRAV GSTLQDFFNG FDALLEHIRT SFGKQATLES SSFLCKELPE GTLMLHYFHP 240
HHTVGFAMLG MIKAAGKRIY HLNVEVEQIE NEKLCFDGSN PSNCSCLTFL IKECETTQIT 300
KDNPQGTSQV PADLRISINT FCRAFPFHLM FDSNMVVLQL GEGLRKQLRY DTHRALKFED 360
CFEIVSPMIN ATFDRVLLRL STPFVIRTKP EASGTENEDK VMEIKGQMIH VPESSAILFL 420
GSPCVDKLDE LMGRGLHLSD IPIHDATRDV ILVGEQAKAQ DGLKKRMDKL KATLERTHQA 480
LEEEKKKTVD LLYSIFPGDV AQQLWQGQQV QARKFDDVTM LFSDIVGFTA ICAQCTPMQV 540
ISMLNELYTR FDHQCGLLDI YKVETIGDAY CVASGLHRKS LCHAKPIALM ALKMMELSEE 600
VLTPDGKAIQ MRIGIHSGSV LAGVVGVRMP RYCLFGNNVT LASKFESGSH PRRINVSPTT 660
YQLLKREDSF TFIPRSREEL PDNFPKEIPG VCYFLELRTD PKPPKPSLSS SRIKKVSYNI 720
GTMFLRETSL 731
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0456--Lyase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR001054--A/G_cyclase
IPR018297--A/G_cyclase_CS
IPR011644--Heme_NO-bd
IPR011645--HNOB_dom_associated
IPR024096--NO_sig/Golgi_transp_ligand-bd
IPR029787--Nucleotide_cyclase
PROSITE

PS00452--GUANYLATE_CYCLASE_1
PS50125--GUANYLATE_CYCLASE_2
Pfam

PF00211--Guanylate_cyc
PF07700--HNOB
PF07701--HNOBA
Gene Ontology

GO:0008074--C:guanylate cyclase complex, soluble
GO:0005886--C:plasma membrane
GO:0004383--F:guanylate cyclase activity
GO:0020037--F:heme binding
GO:0000166--F:nucleotide binding
GO:0035556--P:intracellular signal transduction
GO:0030828--P:positive regulation of cGMP biosynthetic process
GO:0007165--P:signal transduction