dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0051945
Uniprot Accession F8VPZ5; F8VPZ5_MOUSE;
Genbank Protein ID NP_001074690.1; XP_006519183.1;
Genbank Nucleotide ID NM_001081221.1; XM_006519120.2;
Protein Name Protein Ercc6
Protein Synonyms/Alias
Gene Name Ercc6
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 16
PositionPeptidesSourceReferences ( PMIDs )
158NKIIEQLSPQAASNRcurated25338131
163QLSPQAASNRDINRKcurated25338131
227PGPSCLGSMLMPAQEPhosphoSitePlus22135298
428IDDDFFPSSEEEDEAPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 22817900; 21183079; 25338131
429DDDFFPSSEEEDEAMPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 22817900; 21183079; 25338131
482RLKLEDDSEESDAEFPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21743459; 22817900; 21183079; 25338131
485LEDDSEESDAEFDEGPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 21743459; 22817900; 21183079; 25338131
547AFLAGLSYSKIRTRGPhosphoSitePlus22135298
670TPHRIILSGSPMQNNPhosphoSitePlus22135298
886LKMDGTTTIASRQPLPhosphoSitePlus22135298
889DGTTTIASRQPLITKPhosphoSitePlus22135298
1036KCQLKKRTSTVLGTDcurated25338131
1125GDGKHSDSPTVDHTScurated25338131
1182SKRKHDASEEETTEKPhosphoSitePlus;curated22135298; 23684622; 20469934; 25338131
1354KKEGKAHTPEHFSGKcurated25338131
1359AHTPEHFSGKEDGAScurated25338131
Sequence
(Fasta)		MFHEEVPNST HPQEQDCLPS QHANAYKDMP VGQENGGVSE AGECLSSTSC EYGPSTSAEA 60
CVLAATRRGP TLLHIDRHQI PAVEPSAQAL ELQGLGVDVY DQAVLEQGVL QQVDSAMHEA 120
SCVAQLADAE KEYQSVLDDL MSCTTSLRQI NKIIEQLSPQ AASNRDINRK LDSVKRQKYN 180
KEQQLKKITA KQKRLQAILG GAGVQVELDH ASLEEDDAEP GPSCLGSMLM PAQETAWEEL 240
IRTGQMTPFG TPAPQKQEKK PRKIMLNEAS GFEKYLAEQA QLSFERKKQA ATKRTAKKAI 300
VISESSRAAI ETKADQRSQV LSQTDKRLKK HSRKLQRRAL QFQGKVGLPS GKKPLEPEVR 360
PEAEGDTEGE ESGSSPTDGE EEEEQEEEEG VASLSSDDVS YELKPLRKRQ KYQKKVPVQE 420
IDDDFFPSSE EEDEAMEGRG GGRKVARRQD DGDEDYYKQR LRRWNRLRLQ DKEKRLKLED 480
DSEESDAEFD EGFKVPGFLF KKLFKYQQTG VRWLWELHCQ QAGGILGDEM GLGKTIQIIA 540
FLAGLSYSKI RTRGSNYRFE GLGPTIIVCP TTVMHQWVKE FHTWWPPFRV AVLHETGSYT 600
HKKERLIRDI VYCHGVLITS YSYIRLMQDD ISRHDWHYVI LDEGHKIRNP NAAVTLACKQ 660
FRTPHRIILS GSPMQNNLRE LWSLFDFIFP GKLGTLPVFM EQFSVPITMG GYSNASPVQV 720
KTAYKCACVL RDTINPYLLR RMKSDVKMSL SLPDKNEQVL FCRLTDEQHK VYQNFIDSKA 780
VYRILNGENQ IFSGLVALRK ICNHPDLFSG GPKNASGPPE DELEEEQFGH WRRSGKMIVV 840
ESLLKIWHRQ GQRVLLFSQS RQMLHILEVF LRAHKYSYLK MDGTTTIASR QPLITKYNED 900
TSIFVFLLTT RVGGLGVNLT GANRVIIYDP DWNPSTDTQA RERAWRIGQK KQVTVYRLLT 960
AGTIEEKIYH RQIFKQFLTN RVLKDPKQRR FFKSNDLYEL FTLTSPDASQ GTETSAIFAG 1020
TGSSIQTPKC QLKKRTSTVL GTDPKCKKPP VSDTPANAAT LIGEKPKAAG ATGRSVTSGE 1080
SGPFKGDHDT NGNRASSVAF GEETDAGSTL EHLSVMSGDG KHSDSPTVDH TSRPPVEAST 1140
SEKQGSSYAG ARCQAQTEPV PMSEQMEGQF SKYKSKRKHD ASEEETTEKR PQPKQKAKNS 1200
KHCRDAKFEG TRVPHLVKKR RYRQQTSEQE GGAKDRSSDD YVLEKLFKKS VGVHSVVRHD 1260
AIIDGSSPDY VLVEAEANRV AQDALKALRL SRQQCLGAAS GVPTWTGHRG ISGAPTGVKN 1320
RFGQKRDSSL PVQHPSSLTE KTQNNMKKEG KAHTPEHFSG KEDGASVSGA PSSSSLLARM 1380
RARNHMILPE RLESDSEHLA EAAAVPPCGT EHDDLLVDMR NFIAFQAQVD GQASTQEILQ 1440
EFESKLSVAQ SCVFRELLRN LCNFHRTPGG EGIWKLKPEY C 1482
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
Pfam

PF00271--Helicase_C
PF00176--SNF2_N
Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0008023--C:transcription elongation factor complex
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0008094--F:DNA-dependent ATPase activity
GO:0008022--F:protein C-terminus binding
GO:0032403--F:protein complex binding
GO:0047485--F:protein N-terminus binding
GO:0030296--F:protein tyrosine kinase activator activity
GO:0007256--P:activation of JNKK activity
GO:0007257--P:activation of JUN kinase activity
GO:0006284--P:base-excision repair
GO:0006974--P:cellular response to DNA damage stimulus
GO:0006281--P:DNA repair
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0035264--P:multicellular organism growth
GO:0045494--P:photoreceptor cell maintenance
GO:0032786--P:positive regulation of DNA-templated transcription, elongation
GO:0061098--P:positive regulation of protein tyrosine kinase activity
GO:0006290--P:pyrimidine dimer repair
GO:0032784--P:regulation of DNA-templated transcription, elongation
GO:0010332--P:response to gamma radiation
GO:0006979--P:response to oxidative stress
GO:0000303--P:response to superoxide
GO:0009636--P:response to toxic substance
GO:0009411--P:response to UV
GO:0010224--P:response to UV-B
GO:0010165--P:response to X-ray
GO:0006362--P:transcription elongation from RNA polymerase I promoter
GO:0006283--P:transcription-coupled nucleotide-excision repair