dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0051939
Uniprot Accession F8VPS6; F8VPS6_MOUSE;
Genbank Protein ID NP_001074802.1;
Genbank Nucleotide ID NM_001081333.1;
Protein Name Protein Plekhg4
Protein Synonyms/Alias
Gene Name Plekhg4
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
670PPLRKAYSFDRNLGRPhosphoSitePlus;curated22135298; 22817900; 21183079; 25338131
708RGGVRPRSSPPVPLScurated25338131
709GGVRPRSSPPVPLSGcurated21183079
1073RDVRSRASIAVAPFDcurated26160508
Sequence
(Fasta)
MEGPLECGDV SPDSQGHVAD GKRFAVCSFR NTRKEEEPAH EIQAMDPRPS RPAAGATQGV 60
GLQGDFLAKE PQSLPEQRAE DGPRGYQRSI IGAPPTQSEE PAFSELENLL CSGSSHLNLT 120
QGDNDYRGEG LIGDPGPGRT LPAGCSPLSE TSPKLLEADP SGSSFPKPAD CLLARDLAWE 180
LLASGMAALP GTRDVEGRAV LLLCAHSPAW LHPKSNSHEL LSLLFYLRGI PRPEVQALGL 240
TVLVDARVCS PSSSLTWGLS RLQEASPGSV QQVLLIGKMP EDVPVGLQWK QLRSHQSLLT 300
HIPNVELPTS LGGSLSYCHQ GWLDFRMRLE ALQQSCQVAC ALLQGVIDSM KALRPPMESG 360
EVAQLLQQTQ SLMQQVLDSP QLSWLQSQGS QELAWLKQGT PRVTLSPDYR SAVDKADALY 420
GQVDELLHQL ALKSNQRIRA LELLQALEAQ EGVLRQIEVW LQEVGWPGVE EPGEPSLDTL 480
LQAQGPFQEL DLVAQEQVTQ GEKLLQPLVG LEAAELGSPG KRFLALRSQL TEFSRALAQR 540
RQRLADAEKL FQFFKQASTW TEEGRRLLTE LEQERPEVVL QRLQLHWTRH PDLPPAHFRK 600
MWALATGLGS EGIRQECRCA WAQCQDTWLA LDQKREAALK PMPATNNTAT LYVRRAPAVP 660
TVPPLRKAYS FDRNLGRHLQ DVSSRGHCAA IVTDCHRPEA RGGVRPRSSP PVPLSGSSDF 720
RSPNRLQLVL AEMVATEREY VRALDYTIQN YFPELDRPDV PQGLRGQRAH LFGNLEKLRD 780
FHYNFFLREL EACTRHPPRV AHAFLRHRVQ FGMYALYSKN KPRSDALMTN YGHTFFKEKQ 840
QALGDHLDLA SYLLKPIQHM SKYALLLQEL ARACGGPAQE LGALQAAQSL VHFQLRHGND 900
LLAMDAIQGC DVNLKEQGQL VRQDEFTVRA GRHKACRRVF LFEELLLFSK PRRGPAGVDI 960
FTYKRSFKMA DLGLTECCGE SQLRFEIWFR RRKARDLFVL QASDVATKQA WTADISRLLW 1020
RQAVHNKEVR MAEMASMGVG SKAFWDIAPS EEAINDRNIN YVLKRRDVRS RASIAVAPFD 1080
CDNPYLGALG SLPGDRASGS VLGSLNLHLY RDPALMGGHW SLYPPNFSEE ASLDLGSQPS 1140
LTPEDSEVSS QCPSASGSSD SDSSCVSGQT MGRGLEDLSC V 1182
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR011993--PH/PTB_dom
IPR001849--PH_domain

PROSITE

PS50010--DH_2
PS50003--PH_DOMAIN

Pfam

PF00621--RhoGEF

Gene Ontology

GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0090630--P:activation of GTPase activity
GO:0035023--P:regulation of Rho protein signal transduction