dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0051813
Uniprot Accession F6XJP7; F6XJP7_MOUSE;
Genbank Protein ID NP_035178.1;
Genbank Nucleotide ID NM_011048.1;
Protein Name Protein Pcsk6
Protein Synonyms/Alias
Gene Name Pcsk6
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
281TDVVEAKSLGIRPNYPhosphoSitePlus22135298
288SLGIRPNYIDIYSASPhosphoSitePlus22135298
293PNYIDIYSASWGPDDPhosphoSitePlus22135298
Sequence
(Fasta)
MPPRAPPAPG PRPPPRAADV ARGAGAAGRH GLPPLALRPW RWLLLLALPA ACSALPPPRP 60
VYTNHWAVQV LGGPGAADRV AAAHGYLNLG QIGNLDDYYH FYHSKTFKRS TLSSRGPHTF 120
LRMDPQVKWL QQQEVKRRVK RQARSDSLYF NDPIWSNMWY MHCTDKNSRC RSEMNVQAAW 180
KRGYTGKNVV VTILDDGIER NHPDLAPNYD SYASYDVNGN DYDPSPRYDA SNENKHGTRC 240
AGEVAASANN SYCIVGIAYN AKIGGIRMLD GDVTDVVEAK SLGIRPNYID IYSASWGPDD 300
DGKTVDGPGR LAKQAFEYGI KKGRQGLGSI FVWASGNGGR EGDHCSCDGY TNSIYTISVS 360
STTENGHKPW YLEECASTLA TTYSSGAFYE RKIVTTDLRQ RCTDGHTGTS VSAPMVAGII 420
ALALEANNQL TWRDVQHLLV KTSRPAHLKA SDWKVNGAGH KVSHLYGFGL VDAEALVLEA 480
RKWTAVPSQH VCVATADKRP RSIPIVQVLR TTALTNACAD HSDQRVVYLE HVVVRISISH 540
PRRGDLQIHL ISPSGTKSQL LAKRLLDFSN EGFTNWEFMT VHCWGEKAEG EWTLEVQDIP 600
SQVRNPEKQG KLKEWSLILY GTAEHPYRTF SSHQSRSRML ELSVPEQEPP KAAGQPPQAE 660
TPEDEEEYTA PSIQGSPNTL QTSVCHPECG DKGCDGPNAD QCLNCVHFSL GNSKTNRKCV 720
SECPLGYFGD AAARRCRRCH KGCETCTGRS PAQCLSCRRG FYHHQETNTC VTLCPAGLYA 780
DESQRLCLRC HPSCQKCVDE PEKCTVCKEG FSLARGSCIP DCEPGTYFDS ELVKCGECHH 840
TCRTCVGPSR EECIHCAKSF HFQDWKCVPA CGEGFYPEEM PGLPHKVCRR CEENCLSCEG 900
SSRNCSRCKA GFTQLGTSCI TNHTCSNADE TFCEMVKSNR LCERKLFIQF CCRTCLLAG 960
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0720--Serine protease
KW-0732--Signal

Interpro

IPR000742--EGF-like_dom
IPR006212--Furin_repeat
IPR008979--Galactose-bd-like
IPR009030--Growth_fac_rcpt_N_dom
IPR000209--Peptidase_S8/S53_dom
IPR023827--Peptidase_S8_Asp-AS
IPR022398--Peptidase_S8_His-AS
IPR023828--Peptidase_S8_Ser-AS
IPR015500--Peptidase_S8_subtilisin-rel
IPR010909--PLAC
IPR009020--Prot_inh_propept
IPR002884--PrprotnconvertsP

PROSITE

PS50900--PLAC
PS00136--SUBTILASE_ASP
PS00137--SUBTILASE_HIS
PS00138--SUBTILASE_SER

Pfam

PF01483--P_proprotein
PF00082--Peptidase_S8
PF08686--PLAC

Gene Ontology

GO:0009986--C:cell surface
GO:0031012--C:extracellular matrix
GO:0005615--C:extracellular space
GO:0004175--F:endopeptidase activity
GO:0008201--F:heparin binding
GO:0048406--F:nerve growth factor binding
GO:0004252--F:serine-type endopeptidase activity
GO:0007368--P:determination of left/right symmetry
GO:0009100--P:glycoprotein metabolic process
GO:0032902--P:nerve growth factor production
GO:0016486--P:peptide hormone processing
GO:0016485--P:protein processing
GO:0032940--P:secretion by cell
GO:0007354--P:zygotic determination of anterior/posterior axis, embryo