dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0051802
Uniprot Accession F6VSK8; F6VSK8_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Integrin alpha-6
Protein Synonyms/Alias
Gene Name Itga6
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
658AEIHTQPSDKERLTSPhosphoSitePlus;curated22135298; 25266776; 23684622
Sequence
(Fasta)
XFIYHGSPTG IITKPTQVLE GTSPYFGYSI AGNMDLDRNS YPDLAVGSLS DSVTIFRSRP 60
VINILKTITV TPNRIDLRQK SMCGSPSGIC LKVKACFEYT AKPSGYNPPI SILGILEAEK 120
ERRKSGLSSR VQFRNQGSEP KYTQELTLNR QKQRACMEET LWLQENIRDK LRPIPITASV 180
EIQEPSSRRR VNSLPEVLPI LNSNEAKTVQ TDVHFLKEGC GDDNVCNSNL KLEYKFGTRE 240
GNQDKFSYLP IQKGIPELVL KDQKDIALEI TVTNSPSDPR NPRKDGDDAH EAKLIATFPD 300
TLTYSAYREL RAFPEKQLSC VANQNGSQAD CELGNPFKRN SSVTFYLILS TTEVTFDTTD 360
LDINLKLETT SNQDNLAPIT AKAKVVIELL LSVSGVAKPS QVYFGGTVVG EQAMKSEDEV 420
GSLIEYEFRV INLGKPLKNL GTATLNIQWP KEISNGKWLL YLMKVESKGL EQIVCEPHNE 480
INYLKLKESH NSRKKRELPE KQIDDSRKFS LFPERKYQTL NCSVNVRCVN IRCPLRGLDS 540
KASLVLRSRL WNSTFLEEYS KLNYLDILLR ASIDVTAAAQ NIKLPHAGTQ VRVTVFPSKT 600
VAQYSGVAWW IILLAVLAGI LMLALLVFLL WKCGFFKRNK KDHYDATYHK AEIHTQPSDK 660
ERLTSDA 668
Keyword

KW-0130--Cell adhesion
KW-0181--Complete proteome
KW-0401--Integrin
KW-0472--Membrane
KW-1267--Proteomics identification
KW-0675--Receptor
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR013519--Int_alpha_beta-p
IPR000413--Integrin_alpha
IPR013649--Integrin_alpha-2
IPR018184--Integrin_alpha_C_CS

PROSITE

PS51470--FG_GAP
PS00242--INTEGRIN_ALPHA

Pfam

PF00357--Integrin_alpha
PF08441--Integrin_alpha2

Gene Ontology

GO:0045178--C:basal part of cell
GO:0009925--C:basal plasma membrane
GO:0005604--C:basement membrane
GO:0016323--C:basolateral plasma membrane
GO:0009986--C:cell surface
GO:0009897--C:external side of plasma membrane
GO:0005925--C:focal adhesion
GO:0030056--C:hemidesmosome
GO:0008305--C:integrin complex
GO:0005886--C:plasma membrane
GO:0005178--F:integrin binding
GO:0097186--P:amelogenesis
GO:0050873--P:brown fat cell differentiation
GO:0033627--P:cell adhesion mediated by integrin
GO:0007160--P:cell-matrix adhesion
GO:0031589--P:cell-substrate adhesion
GO:0031668--P:cellular response to extracellular stimulus
GO:0048565--P:digestive tract development
GO:0046847--P:filopodium assembly
GO:0007229--P:integrin-mediated signaling pathway
GO:0050900--P:leukocyte migration
GO:0035878--P:nail development
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0042475--P:odontogenesis of dentin-containing tooth
GO:0043065--P:positive regulation of apoptotic process
GO:0022409--P:positive regulation of cell-cell adhesion
GO:0043547--P:positive regulation of GTPase activity
GO:0042327--P:positive regulation of phosphorylation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0072001--P:renal system development
GO:0043588--P:skin development