| Tag |
Content |
| dbPAF ID |
dbPAF-0051801 |
| Uniprot Accession |
F6VR53; F6VR53_MOUSE;
|
| Genbank Protein ID |
|
| Genbank Nucleotide ID |
|
| Protein Name |
Guanine nucleotide exchange factor DBS |
| Protein Synonyms/Alias |
|
| Gene Name |
Mcf2l |
| Gene Synonyms/Alias |
|
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 664 | AKRHEVKSDPTPFGL | PHOSIDA;PhosphoSitePlus;curated | 21081558; 22135298; 21183079 |
|
Sequence
(Fasta) | XSMSQKIAAF TDVGNSLAHV QHLLKDLTAF EEKSSVAVDK ARALSLEGQQ LIENRHYAVD 60
SIHPKCEELQ HLCDHFASEV TRRRGLLSKS LELHSLLETS MKWSDEGIFL LASQPVDKCQ 120
SQDGAEAALQ EIEKFLETGA ENKIQELNEI YKEYECILNQ DLLEHVQKVF QKQESTEEMF 180
HRRQASLKKL AAKQTRPVQP VAPRPEALTK SPSPSPGSWR SSENSSSEGN ALRRGPYRRA 240
KSEMSEPRQG RTSSTGEEEE SLAILRRHVM NELLDTERAY VEELLCVLEG YAAEMDNPLM 300
AHLISTGLQN KKNILFGNME EIYHFHNRIF LRELESCIDC PELVGRCFLE RMEEFQIYEK 360
YCQNKPRSES LWRQCSDCPF FQECQKKLDH KLSLDSYLLK PVQRITKYQL LLKEMLKYSK 420
HCEGAEDLQE ALSSILGILK AVNDSMHLIA ITGYDGNLGD LGKLLMQGSF SVWTDHKKGH 480
TKVKELARFK PMQRHLFLHE KAVLFCKKRE ENGEGYEKAP SYSYKQSLNM TAVGITENVK 540
GDTKKFEIWY NAREEVYIIQ APTPEIKAAW VNEIRKVLTS QLQACREASQ HRALEQSHSL 600
PLPTPSSTSP TKGNTRNVKK LEDRKTDPLS LEGYVSSSLP KPPEKGKASP TSPDKKAKRH 660
EVKSDPTPFG LRGWSKTSHS LEAPEEDGGW SSAEELINSS DAEEDGGVGP KKLVPGKYTV 720
VMDDEKGGPD TLAMRSGDMV EVVEEGAEGL WYVRDLTSSK EGWVPASSLS TLLGKSSSAQ 780
CLSSSGKIHC ARQLCPEPAE ILSPEPV
808Fasta Sequence
>F6VR53|Mcf2l|Mus musculus(Mouse)
XSMSQKIAAFTDVGNSLAHVQHLLKDLTAFEEKSSVAVDKARALSLEGQQLIENRHYAVDSIHPKCEELQHLCDHFASEVTRRRGLLSKSLELHSLLETSMKWSDEGIFLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNEIYKEYECILNQDLLEHVQKVFQKQESTEEMFHRRQASLKKLAAKQTRPVQPVAPRPEALTKSPSPSPGSWRSSENSSSEGNALRRGPYRRAKSEMSEPRQGRTSSTGEEEESLAILRRHVMNELLDTERAYVEELLCVLEGYAAEMDNPLMAHLISTGLQNKKNILFGNMEEIYHFHNRIFLRELESCIDCPELVGRCFLERMEEFQIYEKYCQNKPRSESLWRQCSDCPFFQECQKKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSKHCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKKGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMTAVGITENVKGDTKKFEIWYNAREEVYIIQAPTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSHSLPLPTPSSTSPTKGNTRNVKKLEDRKTDPLSLEGYVSSSLPKPPEKGKASPTSPDKKAKRHEVKSDPTPFGLRGWSKTSHSLEAPEEDGGWSSAEELINSSDAEEDGGVGPKKLVPGKYTVVMDDEKGGPDTLAMRSGDMVEVVEEGAEGLWYVRDLTSSKEGWVPASSLSTLLGKSSSAQCLSSSGKIHCARQLCPEPAEILSPEPV
|
| Keyword |
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
|
| Interpro |
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR001452--SH3_domain
IPR018159--Spectrin/alpha-actinin
IPR002017--Spectrin_repeat
|
| PROSITE |
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3
|
| Pfam |
PF00169--PH
PF00621--RhoGEF
PF00435--Spectrin
|
| Gene Ontology |
GO:0005615--C:extracellular space
GO:0005622--C:intracellular
GO:0030027--C:lamellipodium
GO:0016020--C:membrane
GO:0005545--F:1-phosphatidylinositol binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043547--P:positive regulation of GTPase activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007266--P:Rho protein signal transduction
|
