dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0051777
Uniprot Accession F6T941; F6T941_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Transcription factor E2-alpha
Protein Synonyms/Alias
Gene Name Tcf3
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
513KDLKVPRTRTSSTDEPhosphoSitePlus;curated22135298; 25266776
515LKVPRTRTSSTDEVLPhosphoSitePlus;curated22135298; 25266776
516KVPRTRTSSTDEVLSPhosphoSitePlus;curated22135298; 21183079
517VPRTRTSSTDEVLSLPhosphoSitePlus;curated22135298; 25266776; 21183079; 23984901
518PRTRTSSTDEVLSLEPhosphoSitePlus;curated22135298; 25266776; 21183079
523SSTDEVLSLEEKDLRPhosphoSitePlus;curated22135298; 21183079
Sequence
(Fasta)
XPVGSDKELS DLLDFSMMFP LPVANGKSRP ASLGGTQFAG SGLEDRPSSG SWGSSDQNSS 60
SFDPSRTYSE GAHFSDSHSS LPPSTFLGAG LGGKGSERNA YATFGRDTSV GTLSQAGFLP 120
GELSLSSPGP LSPSGIKSSS QYYPSFPSNP RRRAADGGLA DTQPKKVRKV PPGLPSSVYP 180
PSSGDSYSRD AAAYPSAKTP SSAYPSPFYV ADGSLHPSAE LWSTPSQVGF GPMLGDGSSP 240
LPLAPGSSSV GSGTFGGLQQ QDRMGYQLHG SEVNGSLPAV SSFSAAPGTY SGTSGHTPPV 300
SGAAAESLLG TTASSSGDAL GKALASIYSP DHSSNNFSPS PSTPVGSPQG LPGTSQWPRA 360
GAPSALSPNY DAGLHGLSKM EDRLDEAIHV LRSHAVGTAS DLHGLLPGHG ALTTSFTGPM 420
SLGGRHAGLV GGSHPEEGLT SGASLLHNHA SLPSQPSSLP DLSQRPPDSY SGLGRAGTTA 480
GASEIKREEK EDEEIASVAD AEEDKKDLKV PRTRTSSTDE VLSLEEKDLR DRERRMANNA 540
RERVRVRDIN EAFRELGRMC QLHLKSDKAQ TKLLILQQAV QVILGLEQQV RERNLNPKAA 600
CLKRREEEKV SGVVGDPQLA LSAAHPGLGE AHNPAGHL 639
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR011598--bHLH_dom

PROSITE

PS50888--BHLH

Pfam

PF00010--HLH

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000790--C:nuclear chromatin
GO:0000788--C:nuclear nucleosome
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0090575--C:RNA polymerase II transcription factor complex
GO:0005667--C:transcription factor complex
GO:0043425--F:bHLH transcription factor binding
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0070888--F:E-box binding
GO:0031435--F:mitogen-activated protein kinase kinase kinase binding
GO:0046982--F:protein heterodimerization activity
GO:0042803--F:protein homodimerization activity
GO:0070491--F:repressing transcription factor binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008134--F:transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0070644--F:vitamin D response element binding
GO:0002326--P:B cell lineage commitment
GO:0048468--P:cell development
GO:0043966--P:histone H3 acetylation
GO:0043967--P:histone H4 acetylation
GO:0033152--P:immunoglobulin V(D)J recombination
GO:0030098--P:lymphocyte differentiation
GO:0001779--P:natural killer cell differentiation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048541--P:Peyer's patch development
GO:0030890--P:positive regulation of B cell proliferation
GO:0045787--P:positive regulation of cell cycle
GO:0010628--P:positive regulation of gene expression
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0050821--P:protein stabilization
GO:2000045--P:regulation of G1/S transition of mitotic cell cycle
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006355--P:regulation of transcription, DNA-templated
GO:0042493--P:response to drug
GO:0032496--P:response to lipopolysaccharide
GO:0033077--P:T cell differentiation in thymus
GO:0006351--P:transcription, DNA-templated