| Tag |
Content |
| dbPAF ID |
dbPAF-0051774 |
| Uniprot Accession |
F6SZ47; F6SZ47_MOUSE;
|
| Genbank Protein ID |
|
| Genbank Nucleotide ID |
|
| Protein Name |
Serine/threonine-protein kinase B-raf |
| Protein Synonyms/Alias |
|
| Gene Name |
Braf |
| Gene Synonyms/Alias |
|
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 4 |
Sequence
(Fasta) | QALFNGDMEP EAGAGAAASS AADPAIPEEV WNIKQMIKLT QEHIEALLDK FGGEHNPPSI 60
YLEAYEEYTS KLDALQQREQ QLLESLGNGA DFSVSSSASM DTVTSSSSSS LSVLPSSLSV 120
FQTPTDASRN NPKSPQKPIV RVFLPNKQRT VVPARCGVTV RDSLKKALMM RGLIPECCAV 180
YRIQDGEKKP IGWDTDISWL TGEELHVEVL ENVPLTTHNF VRKTFFTLAF CDFCRKLLFQ 240
GFRCQTCGYK FHQRCSTEVP LMCVNYDQLD LLFVSKFFEH HPVPQEEASF PETALPSGSS 300
SAPPSDSTGP QILTSPSPSK SIPIPQPFRP ADEDHRNQFG QRDRSSSAPN VHINTIEPVN 360
IDDLIRDQGF RGDGGSTTGL SATPPASLPG SLTNVKALQK SPGPQRERKS SSSSSSEDRS 420
RMKTLGRRDS SDDWEIPDGQ ITVGQRIGSG SFGTVYKGKW HGDVAVKMLN VTAPTPQQLQ 480
AFKNEVGVLR KTRHVNILLF MGYSTKPQLA IVTQWCEGSS LYHHLHIIET KFEMIKLIDI 540
ARQTAQGMDY LHAKSIIHRD LKSNNIFLHE DLTVKIGDFG LATVKSRWSG SHQFEQLSGS 600
ILWMAPEVIR MQDKNPYSFQ SDVYAFGIVL YELMTGQLPY SNINNRDQII FMVGRGYLSP 660
DLSKVRSNCP KAMKRLMAEC LKKKRDERPL FPQILASIEL LARSLPKIHR SASEPSLNRA 720
GFQTEDFSLY ACASPKTPIQ AGGYGGFPVH
751Fasta Sequence
>F6SZ47|Braf|Mus musculus(Mouse)
QALFNGDMEPEAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGADFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQTPTDASRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPVPQEEASFPETALPSGSSSAPPSDSTGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSSSEDRSRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGGFPVH
|
| Keyword |
KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0862--Zinc
|
| Interpro |
IPR020454--DAG/PE-bd
IPR011009--Kinase-like_dom
IPR002219--PE/DAG-bd
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR003116--Raf-like_ras-bd
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR029071--Ubiquitin-rel_dom
|
| PROSITE |
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50898--RBD
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2
|
| Pfam |
PF00130--C1_1
PF07714--Pkinase_Tyr
PF02196--RBD
|
| Gene Ontology |
GO:0044297--C:cell body
GO:0005737--C:cytoplasm
GO:0005739--C:mitochondrion
GO:0043005--C:neuron projection
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0005509--F:calcium ion binding
GO:0042802--F:identical protein binding
GO:0004672--F:protein kinase activity
GO:0004674--F:protein serine/threonine kinase activity
GO:0005057--F:receptor signaling protein activity
GO:0046632--P:alpha-beta T cell differentiation
GO:0043367--P:CD4-positive, alpha-beta T cell differentiation
GO:0030154--P:cell differentiation
GO:0071277--P:cellular response to calcium ion
GO:0035690--P:cellular response to drug
GO:0090150--P:establishment of protein localization to membrane
GO:0060324--P:face development
GO:0015758--P:glucose transport
GO:0060323--P:head morphogenesis
GO:0060291--P:long-term synaptic potentiation
GO:0002318--P:myeloid progenitor cell differentiation
GO:0043066--P:negative regulation of apoptotic process
GO:2000352--P:negative regulation of endothelial cell apoptotic process
GO:0010764--P:negative regulation of fibroblast migration
GO:0043524--P:negative regulation of neuron apoptotic process
GO:2000301--P:negative regulation of synaptic vesicle exocytosis
GO:0048680--P:positive regulation of axon regeneration
GO:0050772--P:positive regulation of axonogenesis
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0010628--P:positive regulation of gene expression
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0051496--P:positive regulation of stress fiber assembly
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0043368--P:positive T cell selection
GO:0006468--P:protein phosphorylation
GO:0048679--P:regulation of axon regeneration
GO:0042127--P:regulation of cell proliferation
GO:0035019--P:somatic stem cell population maintenance
GO:0048538--P:thymus development
GO:0030878--P:thyroid gland development
GO:0008542--P:visual learning
|
