dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0051743
Uniprot Accession F6QFD1; F6QFD1_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Protein Synonyms/Alias
Gene Name Pde4d
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
61KTARKSVSPKLSPVIPhosphoSitePlus;curated22135298; 21183079
65KSVSPKLSPVISPRNPhosphoSitePlus;curated22135298; 21743459; 21183079
69PKLSPVISPRNSPRLPhosphoSitePlus;curated22135298; 21743459; 21183079
73PVISPRNSPRLLRRMPhosphoSitePlus22135298
Sequence
(Fasta)		XNCTKLTRKM AQQTTSPDTL TVPEVDNPHV PNPWLNEDLV KSLRENLLQH EKSKTARKSV 60
SPKLSPVISP RNSPRLLRRM LLSSNIPKQR RFTVAHTCFD VDNGTSAGRS PLDPMTSPGS 120
GLILQANFVH SQRRESFLYR SDSDYDLSPK SMSRNSSIAS DIHGDDLIVT PFAQVLASLR 180
TVRNNFAALT NLQDRAPSKR SPMCNQPSIN KATITEEAYQ KLASETLEEL DWCLDQLETL 240
QTRHSVSEMA SNKFKRMLNR ELTHLSEMSR SGNQVSEYIS NTFLDKQHEV EIPSPTQKEK 300
EKKKRPMSQI SGVKKLMHSS SLTNSCIPRF GVKTEQEDVL AKELEDVNKW GLHVFRIAEL 360
SGNRPLTVIM HTIFQERDLL KTFKIPVDTL ITYLMTLEDH YHADVAYHNN IHAADVVQST 420
HVLLSTPALE AVFTDLEILA AIFASAIHDV DHPGVSNQFL INTNSELALM YNDSSVLENH 480
HLAVGFKLLQ EENCDIFQNL TKKQRQSLRK MVIDIVLATD MSKHMNLLAD LKTMVETKKV 540
TSSGVLLLDN YSDRIQVLQN MVHCADLSNP TKPLQLYRQW TDRIMEEFFR QGDRERERGM 600
EISPMCDKHN ASVEKSQVGF IDYIVHPLWE TWADLVHPDA QDILDTLEDN REWYQSTIPQ 660
SPSPAPDDQE EGRQGQTEKF QFELTLEEDC ESDTEKDSGS QVEEDTSCSD SKTLCTQDSE 720
STEIPLDEQV EEEAVAEEES QPETCVPDDC CPDT 755
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR003607--HD/PDEase_dom
IPR023088--PDEase
IPR002073--PDEase_catalytic_dom
IPR023174--PDEase_CS
PROSITE

PS00126--PDEASE_I
Pfam

PF00233--PDEase_I
Gene Ontology

GO:0005813--C:centrosome
GO:0004114--F:3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0046872--F:metal ion binding
GO:0007568--P:aging
GO:0006198--P:cAMP catabolic process
GO:0071222--P:cellular response to lipopolysaccharide
GO:0050900--P:leukocyte migration
GO:0035264--P:multicellular organism growth
GO:0030593--P:neutrophil chemotaxis
GO:0007165--P:signal transduction
GO:0006939--P:smooth muscle contraction